With some risk-taking and luck: A veterinarian’s adventures in viral immunology

por Sigal, Luis J.
Publicado 2018

Activation of CD8 T Lymphocytes during Viral Infections

por Sigal, Luis J.
Publicado 2016

Protective CD8(+) T cell memory without help

por Fang, Min, Sigal, Luis J.
Publicado 2015

Dysregulated anti-viral innate immune cascade during aging

por Stotesbury, Colby, Sigal, Luis J.
Publicado 2021

Bone Marrow–Derived Antigen-Presenting Cells Are Required for the Generation of Cytotoxic T Lymphocyte Responses to Viruses and Use Transporter Associated with Antigen Presentation...

por Sigal, Luis J., Rock, Kenneth L.
Publicado 2000

Age-dependent susceptibility to a viral disease due to decreased natural killer cell numbers and trafficking

por Fang, Min, Roscoe, Felicia, Sigal, Luis J.
Publicado 2010

The natural killer cell dysfunction of aged mice is due to the bone marrow stroma and is not restored by IL-15/IL-15Rα treatment

por Nair, Savita, Fang, Min, Sigal, Luis J
Publicado 2015

A Role for NKG2D in NK Cell–Mediated Resistance to Poxvirus Disease

por Fang, Min, Lanier, Lewis L, Sigal, Luis J
Publicado 2008

Direct Presentation Is Sufficient for an Efficient Anti-Viral CD8(+) T Cell Response

por Xu, Ren-Huan, Remakus, Sanda, Ma, Xueying, Roscoe, Felicia, Sigal, Luis J.
Publicado 2010

Resistance to ectromelia virus infection requires cGAS in bone marrow-derived cells which can be bypassed with cGAMP therapy

por Wong, Eric B., Montoya, Brian, Ferez, Maria, Stotesbury, Colby, Sigal, Luis J.
Publicado 2019

CD94 Is Essential for NK Cell-Mediated Resistance to a Lethal Viral Disease

por Fang, Min, Orr, Mark T., Spee, Pieter, Egebjerg, Thomas, Lanier, Lewis L., Sigal, Luis J.
Publicado 2011

Langerhans Cells Orchestrate the Protective Antiviral Innate Immune Response in the Lymph Node

por Wong, Eric, Montoya, Brian, Stotesbury, Colby, Ferez, Maria, Xu, Ren-Huan, Sigal, Luis J.
Publicado 2019

Defective early innate immune response to ectromelia virus in the draining lymph nodes of aged mice due to impaired dendritic cell accumulation

por Stotesbury, Colby, Wong, Eric B., Tang, Lingjuan, Montoya, Brian, Knudson, Cory J., Melo‐Silva, Carolina R., Sigal, Luis J.
Publicado 2020

Viral infection modulates Qa-1(b) in infected and bystander cells to properly direct NK cell killing

por Ferez, Maria, Knudson, Cory J., Lev, Avital, Wong, Eric B., Alves-Peixoto, Pedro, Tang, Lingjuan, Stotesbury, Colby, Sigal, Luis J.
Publicado 2021

The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination

por Xu, Ren-Huan, Cohen, Matthew, Tang, Yong, Lazear, Eric, Whitbeck, J. Charles, Eisenberg, Roselyn J., Cohen, Gary H., Sigal, Luis J.
Publicado 2008

Development and Function of CD94-Deficient Natural Killer Cells

por Orr, Mark T., Wu, Jun, Fang, Min, Sigal, Luis J., Spee, Pieter, Egebjerg, Thomas, Dissen, Erik, Fossum, Sigbjørn, Phillips, Joseph H., Lanier, Lewis L.
Publicado 2010

Interferon partly dictates a divergent transcriptional response in poxvirus-infected and bystander inflammatory monocytes

por Melo-Silva, Carolina R., Roman, Marisa I., Knudson, Cory J., Tang, Lingjuan, Xu, Ren-Huan, Tassetto, Michel, Dolan, Patrick, Andino, Raul, Sigal, Luis J.
Publicado 2022

Declined miR‐181a‐5p expression is associated with impaired natural killer cell development and function with aging

por Lu, Jiao, Li, Shan, Li, Xiaopeng, Zhao, Wenming, Duan, Xuefeng, Gu, Xiuling, Xu, Jianqiao, Yu, Bolan, Sigal, Luis J., Dong, Zhongjun, Xie, Lixin, Fang, Min
Publicado 2021

Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells

por Melo-Silva, Carolina R., Alves-Peixoto, Pedro, Heath, Natasha, Tang, Lingjuan, Montoya, Brian, Knudson, Cory J., Stotesbury, Colby, Ferez, Maria, Wong, Eric, Sigal, Luis J.
Publicado 2021

Multiple and Consecutive Genome Editing Using i-GONAD and Breeding Enrichment Facilitates the Production of Genetically Modified Mice

por Melo-Silva, Carolina R., Knudson, Cory J., Tang, Lingjuan, Kafle, Samita, Springer, Lauren E., Choi, Jihae, Snyder, Christopher M., Wang, Yajing, Kim, Sangwon V., Sigal, Luis J.
Publicado 2023