The interdependence of isoprenoid synthesis and apicoplast biogenesis in malaria parasites

por Okada, Megan, Sigala, Paul A.
Publicado 2023

Plasmodium heme biosynthesis: To be or not to be essential?

por Goldberg, Daniel E., Sigala, Paul A.
Publicado 2017

Doxycycline has distinct apicoplast-specific mechanisms of antimalarial activity

por Okada, Megan, Guo, Ping, Nalder, Shai-anne, Sigala, Paul A
Publicado 2020

Deconvoluting heme biosynthesis to target blood-stage malaria parasites

por Sigala, Paul A, Crowley, Jan R, Henderson, Jeffrey P, Goldberg, Daniel E
Publicado 2015

Direct Tests of Enzymatic Heme Degradation by the Malaria Parasite Plasmodium falciparum

por Sigala, Paul A., Crowley, Jan R., Hsieh, Samantha, Henderson, Jeffrey P., Goldberg, Daniel E.
Publicado 2012

Divergent acyl carrier protein decouples mitochondrial Fe-S cluster biogenesis from fatty acid synthesis in malaria parasites

por Falekun, Seyi, Sepulveda, Jaime, Jami-Alahmadi, Yasaman, Park, Hahnbeom, Wohlschlegel, James A, Sigala, Paul A
Publicado 2021

Multiple-Streams Focusing-Based Cell Separation in High Viscoelasticity Flow

por Feng, Haidong, Patel, Dhruv, Magda, Jules J., Geher, Sage, Sigala, Paul A., Gale, Bruce K.
Publicado 2022

Critical role for isoprenoids in apicoplast biogenesis by malaria parasites

por Okada, Megan, Rajaram, Krithika, Swift, Russell P, Mixon, Amanda, Maschek, John Alan, Prigge, Sean T, Sigala, Paul A
Publicado 2022

Testing Electrostatic Complementarity in Enzyme Catalysis: Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole

por Kraut, Daniel A, Sigala, Paul A, Pybus, Brandon, Liu, Corey W, Ringe, Dagmar, Petsko, Gregory A, Herschlag, Daniel
Publicado 2006

Direct Tests of Cytochrome Function in the Electron Transport Chain of Malaria Parasites

por Espino-Sanchez, Tanya J., Wienkers, Henry, Marvin, Rebecca G., Nalder, Shai-anne, García-Guerrero, Aldo E., VanNatta, Peter E., Jami-Alahmadi, Yasaman, Blackwell, Amanda Mixon, Whitby, Frank G., Wohlschlegel, James A., Kieber-Emmons, Matthew T., Hill, Christopher P., Sigala, Paul A.
Publicado 2023