Molecular evidence of tissue renin-angiotensin systems: A focus on the brain

por Sakai, Koji, Sigmund, Curt D.
Publicado 2005

The Renin-Angiotensin System in the Central Nervous System and Its Role in Blood Pressure Regulation

por Nakagawa, Pablo, Gomez, Javier, Grobe, Justin L., Sigmund, Curt D.
Publicado 2020

Hypothalamic ERK Mediates the Anorectic and Thermogenic Sympathetic Effects of Leptin

por Rahmouni, Kamal, Sigmund, Curt D., Haynes, William G., Mark, Allyn L.
Publicado 2009

Studies of salt and stress sensitivity on arterial pressure in renin-b deficient mice

por Nakagawa, Pablo, Gomez, Javier, Lu, Ko-Ting, Grobe, Justin L., Sigmund, Curt D.
Publicado 2021

Structure and Function of RhoBTB1 Required for Substrate Specificity and Cullin-3 Ubiquitination

por Kumar, Gaurav, Fang, Shi, Golosova, Daria, Lu, Ko-Ting, Brozoski, Daniel T, Vazirabad, Ibrahim, Sigmund, Curt D
Publicado 2023

Role of Vascular Smooth Muscle PPARγ in Regulating AT(1) Receptor Signaling and Angiotensin II-Dependent Hypertension

por Carrillo-Sepulveda, Maria Alicia, Keen, Henry L., Davis, Deborah R., Grobe, Justin L., Sigmund, Curt D.
Publicado 2014

Collecting Duct Renin Does Not Mediate DOCA-Salt Hypertension or Renal Injury

por Song, Kai, Stuart, Deborah, Abraham, Nikita, Wang, Fei, Wang, Shuping, Yang, Tianxin, Sigmund, Curt D., Kohan, Donald E., Ramkumar, Nirupama
Publicado 2016

Patch-to-Seq and Transcriptomic Analyses Yield Molecular Markers of Functionally Distinct Brainstem Serotonin Neurons

por Mouradian, Gary C., Liu, Pengyuan, Nakagawa, Pablo, Duffy, Erin, Gomez Vargas, Javier, Balapattabi, Kirthikaa, Grobe, Justin L., Sigmund, Curt D., Hodges, Matthew R.
Publicado 2022

Cell-specific transcriptome changes in the hypothalamic arcuate nucleus in a mouse deoxycorticosterone acetate-salt model of hypertension

por Wagner, Valerie A., Deng, Guorui, Claflin, Kristin E., Ritter, McKenzie L., Cui, Huxing, Nakagawa, Pablo, Sigmund, Curt D., Morselli, Lisa L., Grobe, Justin L., Kwitek, Anne E.
Publicado 2023

Endothelial Cullin3 Mutation Impairs Nitric Oxide-Mediated Vasodilation and Promotes Salt-Induced Hypertension

por Wu, Jing, Fang, Shi, Lu, Ko-Ting, Kumar, Gaurav, Reho, John J, Brozoski, Daniel T, Otanwa, Adokole J, Hu, Chunyan, Nair, Anand R, Wackman, Kelsey K, Agbor, Larry N, Grobe, Justin L, Sigmund, Curt D
Publicado 2022

Pregnant mice lacking indoleamine 2,3‐dioxygenase exhibit preeclampsia phenotypes

por Santillan, Mark K., Pelham, Christopher J., Ketsawatsomkron, Pimonrat, Santillan, Donna A., Davis, Deborah R., Devor, Eric J., Gibson‐Corley, Katherine N., Scroggins, Sabrina M., Grobe, Justin L., Yang, Baoli, Hunter, Steven K., Sigmund, Curt D.
Publicado 2015

Methods for the Comprehensive in vivo Analysis of Energy Flux, Fluid Homeostasis, Blood Pressure, and Ventilatory Function in Rodents

por Reho, John J., Nakagawa, Pablo, Mouradian, Gary C., Grobe, Connie C., Saravia, Fatima L., Burnett, Colin M. L., Kwitek, Anne E., Kirby, John R., Segar, Jeffrey L., Hodges, Matthew R., Sigmund, Curt D., Grobe, Justin L.
Publicado 2022

Calcium/Calmodulin-Dependent Kinase II Inhibition in Smooth Muscle Reduces Angiotensin II–Induced Hypertension by Controlling Aortic Remodeling and Baroreceptor Function

por Prasad, Anand M, Morgan, Donald A, Nuno, Daniel W, Ketsawatsomkron, Pimonrat, Bair, Thomas B, Venema, Ashlee N, Dibbern, Megan E, Kutschke, William J, Weiss, Robert M, Lamping, Kathryn G, Chapleau, Mark W, Sigmund, Curt D, Rahmouni, Kamal, Grumbach, Isabella M
Publicado 2015

RhoBTB1 reverses established arterial stiffness in angiotensin II–induced hypertension by promoting actin depolymerization

por Fang, Shi, Wu, Jing, Reho, John J., Lu, Ko-Ting, Brozoski, Daniel T., Kumar, Gaurav, Werthman, Alec M., Silva, Sebastiao Donato, Muskus Veitia, Patricia C., Wackman, Kelsey K., Mathison, Angela J., Teng, Bi Qing, Lin, Chien-Wei, Quelle, Frederick W., Sigmund, Curt D.
Publicado 2022

Mitochondrial-targeted antioxidant attenuates preeclampsia-like phenotypes induced by syncytiotrophoblast-specific Gαq signaling

por Opichka, Megan A., Livergood, M. Christine, Balapattabi, Kirthikaa, Ritter, McKenzie L., Brozoski, Daniel T., Wackman, Kelsey K., Lu, Ko-Ting, Kozak, Kaleigh N., Wells, Clive, Fogo, Agnes B., Gibson-Corley, Katherine N., Kwitek, Anne E., Sigmund, Curt D., McIntosh, Jennifer J., Grobe, Justin L.
Publicado 2023

Genetic Ablation of Prorenin Receptor in the Rostral Ventrolateral Medulla Influences Blood Pressure and Hydromineral Balance in Deoxycorticosterone-Salt Hypertension

por Mathieu, Natalia M, Fekete, Eva M, Muskus, Patricia C, Brozoski, Daniel T, Lu, Ko-Ting, Wackman, Kelsey K, Gomez, Javier, Fang, Shi, Reho, John J, Grobe, Connie C, Vazirabad, Ibrahim, Mouradian, Gary C, Hodges, Matthew R, Segar, Jeffrey L, Grobe, Justin L, Sigmund, Curt D, Nakagawa, Pablo
Publicado 2023

Angiotensin AT(1A) receptor signal switching in Agouti-related peptide neurons mediates metabolic rate adaptation during obesity

por Balapattabi, Kirthikaa, Yavuz, Yavuz, Jiang, Jingwei, Deng, Guorui, Mathieu, Natalia M., Ritter, McKenzie L., Opichka, Megan A., Reho, John J., McCorvy, John D., Nakagawa, Pablo, Morselli, Lisa L., Mouradian, Gary C., Atasoy, Deniz, Cui, Huxing, Hodges, Matthew R., Sigmund, Curt D., Grobe, Justin L.
Publicado 2023