Developmental Stage-Specific Changes in Protein Synthesis Differentially Sensitize Hematopoietic Stem Cells and Erythroid Progenitors to Impaired Ribosome Biogenesis

por Magee, Jeffrey A., Signer, Robert A.J.
Publicado 2021

Haematopoietic stem cells require a highly regulated protein synthesis rate

por Signer, Robert A.J., Magee, Jeffrey A., Salic, Adrian, Morrison, Sean J.
Publicado 2014

Pten Cell Autonomously Modulates the Hematopoietic Stem Cell Response to Inflammatory Cytokines

por Porter, Shaina N., Cluster, Andrew S., Signer, Robert A.J., Voigtmann, Jenna, Monlish, Darlene A., Schuettpelz, Laura G., Magee, Jeffrey A.
Publicado 2016

Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain

por Mich, John K, Signer, Robert AJ, Nakada, Daisuke, Pineda, André, Burgess, Rebecca J, Vue, Tou Yia, Johnson, Jane E, Morrison, Sean J
Publicado 2014

Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal

por Jose, Lorena Hidalgo San, Sunshine, Mary Jean, Dillingham, Christopher H., Chua, Bernadette A., Kruta, Miriama, Hong, Yuning, Hatters, Danny M., Signer, Robert A.J.
Publicado 2020

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

por Signer, Robert A.J., Qi, Le, Zhao, Zhiyu, Thompson, David, Sigova, Alla A., Fan, Zi Peng, DeMartino, George N., Young, Richard A., Sonenberg, Nahum, Morrison, Sean J.
Publicado 2016

Regulation of Mitochondrial Biogenesis in Erythropoiesis by mTORC1-Mediated Protein Translation

por Liu, Xin, Zhang, Yuannyu, Ni, Min, Cao, Hui, Signer, Robert A.J., Li, Dan, Li, Mushan, Gu, Zhimin, Hu, Zeping, Dickerson, Kathryn E., Weinberg, Samuel E., Chandel, Navdeep S., DeBerardinis, Ralph J., Zhou, Feng, Shao, Zhen, Xu, Jian
Publicado 2017