Weakly-supervised tumor purity prediction from frozen H&E stained slides

por Brendel, Matthew, Getseva, Vanesa, Assaad, Majd Al, Sigouros, Michael, Sigaras, Alexandros, Kane, Troy, Khosravi, Pegah, Mosquera, Juan Miguel, Elemento, Olivier, Hajirasouliha, Iman
Publicado 2022

Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer

por Tiwari, Ritika, Manzar, Nishat, Bhatia, Vipul, Yadav, Anjali, Nengroo, Mushtaq A., Datta, Dipak, Carskadon, Shannon, Gupta, Nilesh, Sigouros, Michael, Khani, Francesca, Poutanen, Matti, Zoubeidi, Amina, Beltran, Himisha, Palanisamy, Nallasivam, Ateeq, Bushra
Publicado 2020

Functional comparison of exome capture-based methods for transcriptomic profiling of formalin-fixed paraffin-embedded tumors

por Shohdy, Kyrillus S., Bareja, Rohan, Sigouros, Michael, Wilkes, David C., Dorsaint, Princesca, Manohar, Jyothi, Bockelman, Daniel, Xiang, Jenny Z., Kim, Rob, Ohara, Kentaro, Eng, Kenneth, Mosquera, Juan Miguel, Elemento, Olivier, Sboner, Andrea, Alonso, Alicia, Faltas, Bishoy M.
Publicado 2021

Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis

por Conteduca, Vincenza, Ku, Sheng-Yu, Fernandez, Luisa, Dago-Rodriquez, Angel, Lee, Jerry, Jendrisak, Adam, Slade, Megan, Gilbertson, Cole, Manohar, Jyothi, Sigouros, Michael, Wang, Yipeng, Dittamore, Ryan, Wenstrup, Rick, Mosquera, Juan Miguel, Schonhoft, Joseph D., Beltran, Himisha
Publicado 2021

Author Correction: Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis

por Conteduca, Vincenza, Ku, Sheng-Yu, Fernandez, Luisa, Dago-Rodriquez, Angel, Lee, Jerry, Jendrisak, Adam, Slade, Megan, Gilbertson, Cole, Manohar, Jyothi, Sigouros, Michael, Wang, Yipeng, Dittamore, Ryan, Wenstrup, Rick, Mosquera, Juan Miguel, Schonhoft, Joseph D., Beltran, Himisha
Publicado 2021

Tumor-immune microenvironment revealed by Imaging Mass Cytometry in a metastatic sarcomatoid urothelial carcinoma with a prolonged response to pembrolizumab

por Alnajar, Hussein, Ravichandran, Hiranmayi, Figueiredo Rendeiro, André, Ohara, Kentaro, Al Zoughbi, Wael, Manohar, Jyothi, Greco, Noah, Sigouros, Michael, Fox, Jesse, Muth, Emily, Angiuoli, Samuel, Faltas, Bishoy, Shusterman, Michael, Sternberg, Cora N., Elemento, Olivier, Mosquera, Juan Miguel
Publicado 2022

Androgen receptor variant shows heterogeneous expression in prostate cancer according to differentiation stage

por Gjyrezi, Ada, Galletti, Giuseppe, Zhang, Jiaren, Worroll, Daniel, Sigouros, Michael, Kim, Seaho, Cooley, Victoria, Ballman, Karla V., Ocean, Allyson J., Shah, Manish A., Scandura, Joseph M., Sboner, Andrea, Nanus, David M., Beltran, Himisha, Tagawa, Scott, Giannakakou, Paraskevi
Publicado 2021

Evolution of structural rearrangements in prostate cancer intracranial metastases

por Khani, Francesca, Hooper, William F., Wang, Xiaofei, Chu, Timothy R., Shah, Minita, Winterkorn, Lara, Sigouros, Michael, Conteduca, Vincenza, Pisapia, David, Wobker, Sara, Walker, Sydney, Graff, Julie N., Robinson, Brian, Mosquera, Juan Miguel, Sboner, Andrea, Elemento, Olivier, Robine, Nicolas, Beltran, Himisha
Publicado 2023

Author Correction: Evolution of structural rearrangements in prostate cancer intracranial metastases

por Khani, Francesca, Hooper, William F., Wang, Xiaofei, Chu, Timothy R., Shah, Minita, Winterkorn, Lara, Sigouros, Michael, Conteduca, Vincenza, Pisapia, David, Wobker, Sara, Walker, Sydney, Graff, Julie N., Robinson, Brian, Mosquera, Juan Miguel, Sboner, Andrea, Elemento, Olivier, Robine, Nicolas, Beltran, Himisha
Publicado 2023

Allele-informed copy number evaluation of plasma DNA samples from metastatic prostate cancer patients: the PCF_SELECT consortium assay

por Orlando, Francesco, Romanel, Alessandro, Trujillo, Blanca, Sigouros, Michael, Wetterskog, Daniel, Quaini, Orsetta, Leone, Gianmarco, Xiang, Jenny Z, Wingate, Anna, Tagawa, Scott, Jayaram, Anuradha, Linch, Mark, Jamal-Hanjani, Mariam, Swanton, Charles, Rubin, Mark A, Wyatt, Alexander W, Beltran, Himisha, Attard, Gerhardt, Demichelis, Francesca
Publicado 2022

Case report: Metastatic urothelial cancer with an exceptional response to immunotherapy and comprehensive understanding of the tumor and the tumor microenvironment

por Sternberg, Cora N., Shin, Nara, Chernyshov, Konstantin, Calabro, Fabio, Cerbone, Linda, Procopio, Giuseppe, Miheecheva, Natalia, Sagaradze, Georgy, Zaichikova, Alisa, Samarina, Naira, Boyko, Alexandra, Brown, Jessica H., Yunusova, Leysan, Guevara, Daniela, Manohar, Jyothi, Sigouros, Michael, Al Assaad, Majd, Elemento, Olivier, Mosquera, Juan Miguel
Publicado 2022

Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer

por Brady, Nicholas J., Bagadion, Alyssa M., Singh, Richa, Conteduca, Vincenza, Van Emmenis, Lucie, Arceci, Elisa, Pakula, Hubert, Carelli, Ryan, Khani, Francesca, Bakht, Martin, Sigouros, Michael, Bareja, Rohan, Sboner, Andrea, Elemento, Olivier, Tagawa, Scott, Nanus, David M., Loda, Massimo, Beltran, Himisha, Robinson, Brian, Rickman, David S.
Publicado 2021

Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers

por Setton, Jeremy, Hadi, Kevin, Choo, Zi-Ning, Kuchin, Katherine S., Tian, Huasong, Da Cruz Paula, Arnaud, Rosiene, Joel, Selenica, Pier, Behr, Julie, Yao, Xiaotong, Deshpande, Aditya, Sigouros, Michael, Manohar, Jyothi, Nauseef, Jones T., Mosquera, Juan-Miguel, Elemento, Olivier, Weigelt, Britta, Riaz, Nadeem, Reis-Filho, Jorge S., Powell, Simon N., Imieliński, Marcin
Publicado 2023

Integration of whole-exome and anchored PCR-based next generation sequencing significantly increases detection of actionable alterations in precision oncology

por Beg, Shaham, Bareja, Rohan, Ohara, Kentaro, Eng, Kenneth Wha, Wilkes, David C., Pisapia, David J., Zoughbi, Wael Al, Kudman, Sarah, Zhang, Wei, Rao, Rema, Manohar, Jyothi, Kane, Troy, Sigouros, Michael, Xiang, Jenny Zhaoying, Khani, Francesca, Robinson, Brian D., Faltas, Bishoy M., Sternberg, Cora N., Sboner, Andrea, Beltran, Himisha, Elemento, Olivier, Mosquera, Juan Miguel
Publicado 2020

Patient derived organoids to model rare prostate cancer phenotypes

por Puca, Loredana, Bareja, Rohan, Prandi, Davide, Shaw, Reid, Benelli, Matteo, Karthaus, Wouter R., Hess, Judy, Sigouros, Michael, Donoghue, Adam, Kossai, Myriam, Gao, Dong, Cyrta, Joanna, Sailer, Verena, Vosoughi, Aram, Pauli, Chantal, Churakova, Yelena, Cheung, Cynthia, Deonarine, Lesa Dayal, McNary, Terra J., Rosati, Rachele, Tagawa, Scott T., Nanus, David M., Mosquera, Juan Miguel, Sawyers, Charles L., Chen, Yu, Inghirami, Giorgio, Rao, Rema A., Grandori, Carla, Elemento, Olivier, Sboner, Andrea, Demichelis, Francesca, Rubin, Mark A., Beltran, Himisha
Publicado 2018

Validation of a Circulating Tumor DNA‐Based Next‐Generation Sequencing Assay in a Cohort of Patients with Solid tumors: A Proposed Solution for Decentralized Plasma Testing

por Al Zoughbi, Wael, Fox, Jesse, Beg, Shaham, Papp, Eniko, Hissong, Erika, Ohara, Kentaro, Keefer, Laurel, Sigouros, Michael, Kane, Troy, Bockelman, Daniel, Nichol, Donna, Patchell, Emily, Bareja, Rohan, Karandikar, Aanavi, Alnajar, Hussein, Cerqueira, Gustavo, Guthrie, Violeta Beleva, Verner, Ellen, Manohar, Jyothi, Greco, Noah, Wilkes, David, Tagawa, Scott, Malbari, Murtaza S., Holcomb, Kevin, Eng, Kenneth Wha, Shah, Manish, Altorki, Nasser K., Sboner, Andrea, Nanus, David, Faltas, Bishoy, Sternberg, Cora N., Simmons, John, Houvras, Yariv, Molina, Ana M., Angiuoli, Samuel, Elemento, Olivier, Mosquera, Juan Miguel
Publicado 2021