Short and sweet: How glycans impact prion conversion, cofactor interactions, and cross-species transmission

por Aguilar-Calvo, Patricia, Callender, Julia A., Sigurdson, Christina J.
Publicado 2021

Multimodal fluorescence microscopy of prion strain specific PrP deposits stained by thiophene-based amyloid ligands

por Magnusson, Karin, Simon, Rozalyn, Sjölander, Daniel, Sigurdson, Christina J, Hammarström, Per, Nilsson, K Peter R
Publicado 2014

A Palette of Fluorescent Thiophene-Based Ligands for the Identification of Protein Aggregates

por Shirani, Hamid, Linares, Mathieu, Sigurdson, Christina J, Lindgren, Mikael, Norman, Patrick, Nilsson, K Peter R
Publicado 2015

Structural consequences of sequence variation in mammalian prion β2α2 loop segments

por Glynn, Calina, Hernandez, Evelyn, Gallagher-Jones, Marcus, Miao, Jennifer, Sigurdson, Christina J., Rodriguez, Jose A.
Publicado 2022

Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease

por Kraus, Allison, Saijo, Eri, Metrick, Michael A., Newell, Kathy, Sigurdson, Christina J., Zanusso, Gianluigi, Ghetti, Bernardino, Caughey, Byron
Publicado 2018

Biochemical Properties of Highly Neuroinvasive Prion Strains

por Bett, Cyrus, Joshi-Barr, Shivanjali, Lucero, Melanie, Trejo, Margarita, Liberski, Pawel, Kelly, Jeffery W., Masliah, Eliezer, Sigurdson, Christina J.
Publicado 2012

ARCAM-1 Facilitates Fluorescence Detection of Amyloid-Containing Deposits in the Retina

por Cao, Kevin J., Kim, John H., Kroeger, Heike, Gaffney, Patricia M., Lin, Jonathan H., Sigurdson, Christina J., Yang, Jerry
Publicado 2021

Cellular prion protein in human plasma–derived extracellular vesicles promotes neurite outgrowth via the NMDA receptor–LRP1 receptor system

por Gonias, Steven L., Banki, Michael A., Azmoon, Pardis, Romero, Haylie K., Sigurdson, Christina J., Mantuano, Elisabetta, Campana, Wendy M.
Publicado 2022

The Structural Basis for Optimal Performance of Oligothiophene-Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of...

por Klingstedt, Therése, Shirani, Hamid, Åslund, K O Andreas, Cairns, Nigel J, Sigurdson, Christina J, Goedert, Michel, Nilsson*, K Peter R
Publicado 2013

Solvation-Guided Design of Fluorescent Probes for Discrimination of Amyloids

por Cao, Kevin J., Elbel, Kristyna M., Cifelli, Jessica L., Cirera, Jordi, Sigurdson, Christina J., Paesani, Francesco, Theodorakis, Emmanuel A., Yang, Jerry
Publicado 2018

Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue

por Kollmer, Marius, Close, William, Funk, Leonie, Rasmussen, Jay, Bsoul, Aref, Schierhorn, Angelika, Schmidt, Matthias, Sigurdson, Christina J., Jucker, Mathias, Fändrich, Marcus
Publicado 2019

Experimental Oral Transmission of Chronic Wasting Disease to Reindeer (Rangifer tarandus tarandus)

por Mitchell, Gordon B., Sigurdson, Christina J., O’Rourke, Katherine I., Algire, James, Harrington, Noel P., Walther, Ines, Spraker, Terry R., Balachandran, Aru
Publicado 2012

Minimal change prion retinopathy: Morphometric comparison of retinal and brain prion deposits in Creutzfeldt-Jakob disease

por Goodwill, Vanessa S., Dryden, Ian, Choi, Jihee, De Lillo, Chiara, Soldau, Katrin, Llibre-Guerra, Jorge, Sanchez, Henry, Sigurdson, Christina J., Lin, Jonathan H.
Publicado 2022

Post-translational modifications in PrP expand the conformational diversity of prions in vivo

por Aguilar-Calvo, Patricia, Xiao, Xiangzhu, Bett, Cyrus, Eraña, Hasier, Soldau, Katrin, Castilla, Joaquin, Nilsson, K. Peter R., Surewicz, Witold K., Sigurdson, Christina J.
Publicado 2017

Enhanced neuroinvasion by smaller, soluble prions

por Bett, Cyrus, Lawrence, Jessica, Kurt, Timothy D., Orru, Christina, Aguilar-Calvo, Patricia, Kincaid, Anthony E., Surewicz, Witold K., Caughey, Byron, Wu, Chengbiao, Sigurdson, Christina J.
Publicado 2017

Distinct conformers of amyloid beta accumulate in the neocortex of patients with rapidly progressive Alzheimer's disease

por Liu, He, Kim, Chae, Haldiman, Tracy, Sigurdson, Christina J., Nyström, Sofie, Nilsson, K. Peter R., Cohen, Mark L., Wisniewski, Thomas, Hammarström, Per, Safar, Jiri G.
Publicado 2021

Defining the Conformational Features of Anchorless, Poorly Neuroinvasive Prions

por Bett, Cyrus, Kurt, Tim D., Lucero, Melanie, Trejo, Margarita, Rozemuller, Annemieke J., Kong, Qingzhong, Nilsson, K. Peter R., Masliah, Eliezer, Oldstone, Michael B., Sigurdson, Christina J.
Publicado 2013

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein

por Sandberg, Malin K., Al-Doujaily, Huda, Sigurdson, Christina J., Glatzel, Markus, O'Malley, Catherine, Powell, Caroline, Asante, Emmanuel A., Linehan, Jacqueline M., Brandner, Sebastian, Wadsworth, Jonathan D. F., Collinge, John
Publicado 2010

TDP43 pathology in chronic traumatic encephalopathy retinas

por Phansalkar, Ragini, Goodwill, Vanessa S., Nirschl, Jeffrey J., De Lillo, Chiara, Choi, Jihee, Spurlock, Elizabeth, Coughlin, David G., Pizzo, Donald, Sigurdson, Christina J., Hiniker, Annie, Alvarez, Victor E., Mckee, Ann C., Lin, Jonathan H.
Publicado 2023

PK-sensitive PrP(Sc) Is Infectious and Shares Basic Structural Features with PK-resistant PrP(Sc)

por Sajnani, Gustavo, Silva, Christopher J., Ramos, Adriana, Pastrana, Miguel A., Onisko, Bruce C., Erickson, Melissa L., Antaki, Elizabeth M., Dynin, Irina, Vázquez-Fernández, Ester, Sigurdson, Christina J., Carter, J. Mark, Requena, Jesús R.
Publicado 2012