Identification of a key residue in K(v)7.1 potassium channel essential for sensing external potassium ions

por Wang, Wenying, Flores, Maria Cristina Perez, Sihn, Choong-Ryoul, Kim, Hyo Jeong, Zhang, Yinuo, Doyle, Karen J., Chiamvimonvat, Nipavan, Zhang, Xiao-Dong, Yamoah, Ebenezer N.
Publicado 2015

Prednisolone Does Not Regulate Factor VIII Expression in Mice Receiving AAV5-hFVIII-SQ: Valoctocogene Roxaparvovec

por Zhang, Lening, Handyside, Britta, Murphy, Ryan, Sihn, Choong-Ryoul, Xie, Lin, Vitelli, Catherine, Harmon, Danielle, Sisó, Sílvia, Liu, Su, Bullens, Sherry, Bunting, Stuart, Fong, Sylvia
Publicado 2019

Molecular analysis of AAV5-hFVIII-SQ vector-genome-processing kinetics in transduced mouse and nonhuman primate livers

por Sihn, Choong-Ryoul, Handyside, Britta, Liu, Su, Zhang, Lening, Murphy, Ryan, Yates, Bridget, Xie, Lin, Torres, Richard, Russell, Chris B., O'Neill, Charles A., Pungor, Erno, Bunting, Stuart, Fong, Sylvia
Publicado 2021

Interindividual variability in transgene mRNA and protein production following adeno-associated virus gene therapy for hemophilia A

por Fong, Sylvia, Yates, Bridget, Sihn, Choong-Ryoul, Mattis, Aras N., Mitchell, Nina, Liu, Su, Russell, Chris B., Kim, Benjamin, Lawal, Adebayo, Rangarajan, Savita, Lester, Will, Bunting, Stuart, Pierce, Glenn F., Pasi, K. John, Wong, Wing Yen
Publicado 2022

Cooperativity of K(v)7.4 channels confers ultrafast electromechanical sensitivity and emergent properties in cochlear outer hair cells

por Perez-Flores, Maria C., Lee, Jeong H., Park, Seojin, Zhang, Xiao-Dong, Sihn, Choong-Ryoul, Ledford, Hannah A., Wang, Wenying, Kim, Hyo Jeong, Timofeyev, Valeriy, Yarov-Yarovoy, Vladimir, Chiamvimonvat, Nipavan, Rabbitt, Richard D., Yamoah, Ebenezer N.
Publicado 2020

Application of in-vitro-cultured primary hepatocytes to evaluate species translatability and AAV transduction mechanisms of action

por Liu, Su, Razon, Lisa, Ritchie, Olivia, Sihn, Choong-Ryoul, Handyside, Britta, Berguig, Geoffrey, Woloszynek, Jill, Zhang, Lening, Batty, Paul, Lillicrap, David, Agrawal, Vishal, Cortesio, Christa, Gebretsadik, Kahsay, Akeefe, Hassibullah, Colosi, Peter, Kim, Benjamin, Bunting, Stuart, Fong, Sylvia
Publicado 2022

Different arrhythmia-associated calmodulin mutations have distinct effects on cardiac SK channel regulation

por Ledford, Hannah A., Park, Seojin, Muir, Duncan, Woltz, Ryan L., Ren, Lu, Nguyen, Phuong T., Sirish, Padmini, Wang, Wenying, Sihn, Choong-Ryoul, George, Alfred L., Knollmann, Björn C., Yamoah, Ebenezer N., Yarov-Yarovoy, Vladimir, Zhang, Xiao-Dong, Chiamvimonvat, Nipavan
Publicado 2020

Gene Therapy with BMN 270 Results in Therapeutic Levels of FVIII in Mice and Primates and Normalization of Bleeding in Hemophilic Mice

por Bunting, Stuart, Zhang, Lening, Xie, Lin, Bullens, Sherry, Mahimkar, Rajeev, Fong, Sylvia, Sandza, Krystal, Harmon, Danielle, Yates, Bridget, Handyside, Britta, Sihn, Choong-Ryoul, Galicia, Nicole, Tsuruda, Laurie, O’Neill, Charles A., Bagri, Anil, Colosi, Peter, Long, Shinong, Vehar, Gordon, Carter, Barrie
Publicado 2018

Prestin amplifies cardiac motor functions

por Zhang, Xiao-Dong, Thai, Phung N., Ren, Lu, Flores, Maria Cristina Perez, Ledford, Hannah A., Park, Seojin, Lee, Jeong Han, Sihn, Choong-Ryoul, Chang, Che-Wei, Chen, Wei Chun, Timofeyev, Valeriy, Zuo, Jian, Chan, James W., Yamoah, Ebenezer N., Chiamvimonvat, Nipavan
Publicado 2021

Induction of ER Stress by an AAV5 BDD FVIII Construct Is Dependent on the Strength of the Hepatic-Specific Promoter

por Fong, Sylvia, Handyside, Britta, Sihn, Choong-Ryoul, Liu, Su, Zhang, Lening, Xie, Lin, Murphy, Ryan, Galicia, Nicole, Yates, Bridget, Minto, Wesley C., Vitelli, Catherine, Harmon, Danielle, Ru, Yuanbin, Yu, Guoying Karen, Escher, Claudia, Vowinckel, Jakob, Woloszynek, Jill, Akeefe, Hassib, Mahimkar, Rajeev, Bullens, Sherry, Bunting, Stuart
Publicado 2020

Young mice administered adult doses of AAV5-hFVIII-SQ achieve therapeutic factor VIII expression into adulthood

por Zhang, Lening, Yates, Bridget, Murphy, Ryan, Liu, Su, Xie, Lin, Handyside, Britta, Sihn, Choong-Ryoul, Bouwman, Taren, Galicia, Nicole, Tan, Danielle, Fonck, Carlos, Arens, Jeremy, Clark, Annie, Zhang, Weiming, Chandra, Sundeep, Srimani, Jaydeep, Holcomb, Jennifer, Van Tuyl, Andrea, Henshaw, Joshua, Vettermann, Christian, Siso, Silvia, Su, Cheng, Bullens, Sherry, Bunting, Stuart, O’Neill, Charles, Fong, Sylvia
Publicado 2022

The Piezo channel is central to the mechano-sensitive channel complex in the mammalian inner ear

por Lee, Jeong Han, Perez-Flores, Maria C., Park, Seojin, Kim, Hyo Jeong, Chen, Yingying, Kang, Mincheol, Kersigo, Jennifer, Choi, Jinsil, Thai, Phung N., Woltz, Ryan, Perez-Flores, Dolores Columba, Perkins, Guy, Sihn, Choong-Ryoul, Trinh, Pauline, Zhang, Xiao-Dong, Sirish, Padmini, Dong, Yao, Feng, Wayne Wei, Pessah, Isaac N., Dixon, Rose E., Sokolowski, Bernd, Fritzsch, Bernd, Chiamvimonvat, Nipavan, Yamoah, Ebenezer N.
Publicado 2023