Metformin Strongly Affects Gut Microbiome Composition in High-Fat Diet-Induced Type 2 Diabetes Mouse Model of Both Sexes

por Silamiķele, Laila, Silamiķelis, Ivars, Ustinova, Monta, Kalniņa, Zane, Elbere, Ilze, Petrovska, Ramona, Kalniņa, Ineta, Kloviņš, Jānis
Publicado 2021

Metformin targets intestinal immune system signaling pathways in a high-fat diet-induced mouse model of obesity and insulin resistance

por Brīvība, Monta, Silamiķele, Laila, Kalniņa, Ineta, Silamiķelis, Ivars, Birzniece, Līga, Ansone, Laura, Jagare, Lauma, Elbere, Ilze, Kloviņš, Jānis
Publicado 2023

Spatial variation of the gut microbiome in response to long-term metformin treatment in high-fat diet-induced type 2 diabetes mouse model of both sexes

por Silamiķele, Laila, Saksis, Rihards, Silamiķelis, Ivars, Kotoviča, Patrīcija Paulīne, Brīvība, Monta, Kalniņa, Ineta, Kalniņa, Zane, Fridmanis, Dāvids, Kloviņš, Jānis
Publicado 2023

Exercise-Induced Extracellular Vesicles Delay the Progression of Prostate Cancer

por Sadovska, Lilite, Auders, Jānis, Keiša, Laura, Romanchikova, Nadezhda, Silamiķele, Laila, Kreišmane, Madara, Zayakin, Pawel, Takahashi, Satoru, Kalniņa, Zane, Linē, Aija
Publicado 2022

Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia

por Ustinova, Monta, Peculis, Raitis, Rescenko, Raimonds, Rovite, Vita, Zaharenko, Linda, Elbere, Ilze, Silamikele, Laila, Konrade, Ilze, Sokolovska, Jelizaveta, Pirags, Valdis, Klovins, Janis
Publicado 2021

Whole-blood transcriptome profiling reveals signatures of metformin and its therapeutic response

por Ustinova, Monta, Ansone, Laura, Silamikelis, Ivars, Rovite, Vita, Elbere, Ilze, Silamikele, Laila, Kalnina, Ineta, Fridmanis, Davids, Sokolovska, Jelizaveta, Konrade, Ilze, Pirags, Valdis, Klovins, Janis
Publicado 2020

Baseline gut microbiome composition predicts metformin therapy short-term efficacy in newly diagnosed type 2 diabetes patients

por Elbere, Ilze, Silamikelis, Ivars, Dindune, Ilze Izabella, Kalnina, Ineta, Ustinova, Monta, Zaharenko, Linda, Silamikele, Laila, Rovite, Vita, Gudra, Dita, Konrade, Ilze, Sokolovska, Jelizaveta, Pirags, Valdis, Klovins, Janis
Publicado 2020

First Report on the Latvian SARS-CoV-2 Isolate Genetic Diversity

por Zrelovs, Nikita, Ustinova, Monta, Silamikelis, Ivars, Birzniece, Liga, Megnis, Kaspars, Rovite, Vita, Freimane, Lauma, Silamikele, Laila, Ansone, Laura, Pjalkovskis, Janis, Fridmanis, Davids, Vilne, Baiba, Priedite, Marta, Caica, Anastasija, Gavars, Mikus, Perminov, Dmitry, Storozenko, Jelena, Savicka, Oksana, Dimina, Elina, Dumpis, Uga, Klovins, Janis
Publicado 2021