Future Therapeutic Directions for Smac-Mimetics

por Morrish, Emma, Brumatti, Gabriela, Silke, John
Publicado 2020

An overview of mammalian p38 mitogen-activated protein kinases, central regulators of cell stress and receptor signaling

por Han, Jiahuai, Wu, Jianfeng, Silke, John
Publicado 2020

NF-κB and Pancreatic Cancer; Chapter and Verse

por Silke, John, O’Reilly, Lorraine Ann
Publicado 2021

Digesting the Role of JAK-STAT and Cytokine Signaling in Oral and Gastric Cancers

por Ni, Yanhong, Low, Jun T., Silke, John, O’Reilly, Lorraine A.
Publicado 2022

The Immuno-Modulatory Effects of Inhibitor of Apoptosis Protein Antagonists in Cancer Immunotherapy

por Michie, Jessica, Kearney, Conor J., Hawkins, Edwin D., Silke, John, Oliaro, Jane
Publicado 2020

Diablo Promotes Apoptosis by Removing Miha/Xiap from Processed Caspase 9

por Ekert, Paul G., Silke, John, Hawkins, Christine J., Verhagen, Anne M., Vaux, David L.
Publicado 2001

Combinatorial Treatment of Birinapant and Zosuquidar Enhances Effective Control of HBV Replication In Vivo

por Morrish, Emma, Mackiewicz, Liana, Silke, Natasha, Pellegrini, Marc, Silke, John, Brumatti, Gabriela, Ebert, Gregor
Publicado 2020

Deletion of Gpatch2 does not alter Tnf expression in mice

por Dalseno, Destiny, Anderton, Holly, Kueh, Andrew, Herold, Marco J, Silke, John, Strasser, Andreas, Bouillet, Philippe
Publicado 2023

Effect of Immunosuppressive Agents on Hepatocyte Apoptosis Post-Liver Transplantation

por Lim, Eu Jin, Chin, Ruth, Nachbur, Ueli, Silke, John, Jia, Zhiyuan, Angus, Peter W., Torresi, Joseph
Publicado 2015

OR05-06 Histone Deacetylase Inhibitor, Panobinostat, In Combination With A Smac-mimetic For The Treatment Of Ovarian Granulosa Cell Tumours

por Chu, Simon, Carolan, Ashleigh, Giatrakis, Chrissie, Nguyen, Trang, Alexiadis, Maria, Yu, Tianzhi, Silke, John, Fuller, Peter J
Publicado 2023

The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family

por Wang, Xiangyi S., Cotton, Thomas R., Trevelyan, Sarah J., Richardson, Lachlan W., Lee, Wei Ting, Silke, John, Lechtenberg, Bernhard C.
Publicado 2023

High molecular weight hyaluronic acid drastically reduces chemotherapy-induced mucositis and apoptotic cell death

por Mohammed, Ali I., Celentano, Antonio, Paolini, Rita, Low, Jun T., Silke, John, O’ Reilly, Lorraine A., McCullough, Michael, Cirillo, Nicola
Publicado 2023

Cellular IAPs inhibit a cryptic CD95-induced cell death by limiting RIP1 kinase recruitment

por Geserick, Peter, Hupe, Mike, Moulin, Maryline, Wong, W. Wei-Lynn, Feoktistova, Maria, Kellert, Beate, Gollnick, Harald, Silke, John, Leverkus, Martin
Publicado 2009

The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3– and caspase 9–interacting sites

por Silke, John, Hawkins, Christine J., Ekert, Paul G., Chew, Joanne, Day, Catherine L., Pakusch, Miha, Verhagen, Anne M., Vaux, David L.
Publicado 2002

Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die

por Ekert, Paul G., Read, Stuart H., Silke, John, Marsden, Vanessa S., Kaufmann, Hitto, Hawkins, Christine J., Gerl, Robert, Kumar, Sharad, Vaux, David L.
Publicado 2004

The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis

por Moujalled, Diane, Gangatirkar, Pradnya, Kauppi, Maria, Corbin, Jason, Lebois, Marion, Murphy, James M., Lalaoui, Najoua, Hildebrand, Joanne M., Silke, John, Alexander, Warren S., Josefsson, Emma C.
Publicado 2021

Necroptotic signaling is primed in Mycobacterium tuberculosis-infected macrophages, but its pathophysiological consequence in disease is restricted

por Stutz, Michael D., Ojaimi, Samar, Allison, Cody, Preston, Simon, Arandjelovic, Philip, Hildebrand, Joanne M., Sandow, Jarrod J., Webb, Andrew I., Silke, John, Alexander, Warren S., Pellegrini, Marc
Publicado 2017

cIAPs control RIPK1 kinase activity‐dependent and ‐independent cell death and tissue inflammation

por Schorn, Fabian, Werthenbach, J Paul, Hoffmann, Mattes, Daoud, Mila, Stachelscheid, Johanna, Schiffmann, Lars M, Hildebrandt, Ximena, Lyu, Su Ir, Peltzer, Nieves, Quaas, Alexander, Vucic, Domagoj, Silke, John, Pasparakis, Manolis, Kashkar, Hamid
Publicado 2023

OXTR(High) stroma fibroblasts control the invasion pattern of oral squamous cell carcinoma via ERK5 signaling

por Ding, Liang, Fu, Yong, Zhu, Nisha, Zhao, Mengxiang, Ding, Zhuang, Zhang, Xiaoxin, Song, Yuxian, Jing, Yue, Zhang, Qian, Chen, Sheng, Huang, Xiaofeng, O’Reilly, Lorraine A, Silke, John, Hu, Qingang, Ni, Yanhong
Publicado 2022

TAK1 Is Required for Survival of Mouse Fibroblasts Treated with TRAIL, and Does So by NF-κB Dependent Induction of cFLIPL

por Lluis, Josep Maria, Nachbur, Ulrich, Cook, Wendy Diane, Gentle, Ian Edward, Moujalled, Donia, Moulin, Maryline, Wong, Wendy Wei-Lynn, Khan, Nufail, Chau, Diep, Callus, Bernard Andrew, Vince, James Edward, Silke, John, Vaux, David Lawrence
Publicado 2010