The Native Copper- and Zinc- Binding Protein Metallothionein Blocks Copper-Mediated Aβ Aggregation and Toxicity in Rat Cortical Neurons

por Chung, Roger S., Howells, Claire, Eaton, Emma D., Shabala, Lana, Zovo, Kairit, Palumaa, Peep, Sillard, Rannar, Woodhouse, Adele, Bennett, William R., Ray, Shannon, Vickers, James C., West, Adrian K.
Publicado 2010

Novel Orthogonally Hydrocarbon-Modified Cell-Penetrating Peptide Nanoparticles Mediate Efficient Delivery of Splice-Switching Antisense Oligonucleotides In Vitro and In Vivo

por Bazaz, Safa, Lehto, Tõnis, Tops, Rahel, Gissberg, Olof, Gupta, Dhanu, Bestas, Burcu, Bost, Jeremy, Wiklander, Oscar P. B., Sork, Helena, Zaghloul, Eman M., Mamand, Doste R., Hällbrink, Mattias, Sillard, Rannar, Saher, Osama, Ezzat, Kariem, Smith, C. I. Edvard, Andaloussi, Samir EL, Lehto, Taavi
Publicado 2021

PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation

por Ezzat, Kariem, EL Andaloussi, Samir, Zaghloul, Eman M., Lehto, Taavi, Lindberg, Staffan, Moreno, Pedro M. D., Viola, Joana R., Magdy, Tarek, Abdo, Rania, Guterstam, Peter, Sillard, Rannar, Hammond, Suzan M., Wood, Matthew J. A., Arzumanov, Andrey A., Gait, Michael J., Smith, C. I. Edvard, Hällbrink, Mattias, Langel, Ülo
Publicado 2011

Design of a peptide-based vector, PepFect6, for efficient delivery of siRNA in cell culture and systemically in vivo

por EL Andaloussi, Samir, Lehto, Taavi, Mäger, Imre, Rosenthal-Aizman, Katri, Oprea, Iulian I., Simonson, Oscar E., Sork, Helena, Ezzat, Kariem, Copolovici, Dana M., Kurrikoff, Kaido, Viola, Joana R., Zaghloul, Eman M., Sillard, Rannar, Johansson, Henrik J., Said Hassane, Fatouma, Guterstam, Peter, Suhorutšenko, Julia, Moreno, Pedro M. D., Oskolkov, Nikita, Hälldin, Jonas, Tedebark, Ulf, Metspalu, Andres, Lebleu, Bernard, Lehtiö, Janne, Smith, C. I. Edvard, Langel, Ülo
Publicado 2011