From Inflammation to Fibrosis—Molecular and Cellular Mechanisms of Myocardial Tissue Remodelling and Perspectives on Differential Treatment Opportunities

por Suthahar, Navin, Meijers, Wouter C., Silljé, Herman H.W., de Boer, Rudolf A.
Publicado 2017

Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure

por Yin, Meimei, Silljé, Herman HW, Meissner, Maxi, van Gilst, Wiek H, de Boer, Rudolf A
Publicado 2011

A combined bioinformatics, experimental and clinical approach to identify novel cardiac‐specific heart failure biomarkers: is Dickkopf‐3 (DKK3) a possible candidate?

por Piek, Arnold, Suthahar, Navin, Voors, Adriaan A., de Boer, Rudolf A., Silljé, Herman H.W.
Publicado 2020

Human TPX2 is required for targeting Aurora-A kinase to the spindle

por Kufer, Thomas A., Silljé, Herman H.W., Körner, Roman, Gruss, Oliver J., Meraldi, Patrick, Nigg, Erich A.
Publicado 2002

Galectin-3 Activation and Inhibition in Heart Failure and Cardiovascular Disease: An Update

por Suthahar, Navin, Meijers, Wouter C., Silljé, Herman H.W., Ho, Jennifer E., Liu, Fu-Tong, de Boer, Rudolf A.
Publicado 2018

Evaluation of renal cancer progression in a mouse model of heart failure

por Shi, Canxia, Aboumsallem, Joseph Pierre, de Wit, Sanne, Schouten, Elisabeth Maria, Bracun, Valentina, Meijers, Wouter C., Silljé, Herman H.W., de Boer, Rudolf A.
Publicado 2021

Circulating immune checkpoints predict heart failure outcomes

por Screever, Elles M., Yousif, Laura I.E., Moslehi, Javid J., Salem, Joe‐Elie, Voors, Adriaan A., Silljé, Herman H.W., de Boer, Rudolf A., Meijers, Wouter C.
Publicado 2023

Plasma levels of heart failure biomarkers are primarily a reflection of extracardiac production

por Du, Weijie, Piek, Arnold, Schouten, E. Marloes, van de Kolk, Cees W.A., Mueller, Christian, Mebazaa, Alexandre, Voors, Adriaan A., de Boer, Rudolf A., Silljé, Herman H.W.
Publicado 2018

Clinical Outcome in KLHL24 Cardiomyopathy

por Vermeer, Mathilde C.S.C., Arevalo Gomez, Karla F., Hoes, Martijn F., Tromp, Jasper, Verdonschot, Job A.J., Henkens, Michiel T.H.M., Silljé, Herman H.W., Bolling, Maria C., van der Meer, Peter
Publicado 2023

A translation re‐initiation variant in KLHL24 also causes epidermolysis bullosa simplex and dilated cardiomyopathy via intermediate filament degradation

por Vermeer, Mathilde C.S.C., Al‐Shinnag, Mohammad, Silljé, Herman H.W., Gaytan, Antonio Esquivel, Murrell, Dedee F., McGaughran, Julie, Melbourne, Wei, Cowan, Timothy, van den Akker, Peter C., van Spaendonck‐Zwarts, Karin Y., van der Meer, Peter, Bolling, Maria C.
Publicado 2022

Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure

por Yurista, Salva R., Matsuura, Timothy R., Silljé, Herman H.W., Nijholt, Kirsten T., McDaid, Kendra S., Shewale, Swapnil V., Leone, Teresa C., Newman, John C., Verdin, Eric, van Veldhuisen, Dirk J., de Boer, Rudolf A., Kelly, Daniel P., Westenbrink, B. Daan
Publicado 2020

Cardiac LXRα protects against pathological cardiac hypertrophy and dysfunction by enhancing glucose uptake and utilization

por Cannon, Megan V, Silljé, Herman HW, Sijbesma, Jürgen WA, Vreeswijk-Baudoin, Inge, Ciapaite, Jolita, van der Sluis, Bart, van Deursen, Jan, Silva, Gustavo JJ, de Windt, Leon J, Gustafsson, Jan-Åke, van der Harst, Pim, van Gilst, Wiek H, de Boer, Rudolf A
Publicado 2015

Selenoprotein DIO2 Is a Regulator of Mitochondrial Function, Morphology and UPRmt in Human Cardiomyocytes

por Bomer, Nils, Pavez-Giani, Mario G., Deiman, Frederik E., Linders, Annet N., Hoes, Martijn F., Baierl, Christiane L.J., Oberdorf-Maass, Silke U., de Boer, Rudolf A., Silljé, Herman H.W., Berezikov, Eugene, Simonides, Warner S., Westenbrink, B. Daan, van der Meer, Peter
Publicado 2021

Protein Aggregation Is an Early Manifestation of Phospholamban p.(Arg14del)–Related Cardiomyopathy: Development of PLN-R14del–Related Cardiomyopathy

por Eijgenraam, Tim R., Boogerd, Cornelis J., Stege, Nienke M., Oliveira Nunes Teixeira, Vivian, Dokter, Martin M., Schmidt, Lukas E., Yin, Xiaoke, Theofilatos, Konstantinos, Mayr, Manuel, van der Meer, Peter, van Rooij, Eva, van der Velden, Jolanda, Silljé, Herman H.W., de Boer, Rudolf A.
Publicado 2021

Fibrotic Marker Galectin-3 Identifies Males at Risk of Developing Cancer and Heart Failure

por van den Berg, Pieter F., Aboumsallem, Joseph Pierre, Screever, Elles M., Shi, Canxia, de Wit, Sanne, Bracun, Valentina, Yousif, Laura I., Geerlings, Lotte, Wang, Dongyu, Ho, Jennifer E., Bakker, Stephan J.L., van der Vegt, Bert, Silljé, Herman H.W., de Boer, Rudolf A., Meijers, Wouter C.
Publicado 2023

Clonal haematopoiesis of indeterminate potential: associations with heart failure incidence, clinical parameters and biomarkers

por Shi, Canxia, Aboumsallem, Joseph Pierre, Suthahar, Navin, de Graaf, Aniek O., Jansen, Joop H., van Zeventer, Isabelle A., Bracun, Valentina, de Wit, Sanne, Screever, Elles M., van den Berg, Pieter F., Meijers, Wouter C., Gansevoort, Ron T., Bakker, Stephan J.L., van der Harst, Pim, Silljé, Herman H.W., Huls, Gerwin, de Boer, Rudolf A.
Publicado 2022

Evaluation of Senescence and Its Prevention in Doxorubicin-Induced Cardiotoxicity Using Dynamic Engineered Heart Tissues

por Linders, Annet N., Dias, Itamar B., Ovchinnikova, Ekaterina S., Vermeer, Mathilde C.S.C., Hoes, Martijn F., Markousis Mavrogenis, George, Deiman, Frederik E., Arevalo Gomez, Karla F., Bliley, Jacqueline M., Nehme, Jamil, Vink, Aryan, Gietema, Jourik, de Boer, Rudolf A., Westenbrink, Daan, Sillje, Herman H.W., Hilfiker-Kleiner, Denise, van Laake, Linda W., Feinberg, Adam W., Demaria, Marco, Bomer, Nils, van der Meer, Peter
Publicado 2023