Structure and Activity of a Novel Archaeal β-CASP Protein with N-Terminal KH Domains

por Silva, Ana P.G., Chechik, Maria, Byrne, Robert T., Waterman, David G., Ng, C. Leong, Dodson, Eleanor J., Koonin, Eugene V., Antson, Alfred A., Smits, Callum
Publicado 2011

Synthesis and Evaluation of α-Thymidine Analogues as Novel Antimalarials

por Cui, Huaqing, Carrero-Lérida, Juana, Silva, Ana P. G., Whittingham, Jean L., Brannigan, James A., Ruiz-Pérez, Luis M., Read, Kevin D., Wilson, Keith S., González-Pacanowska, Dolores, Gilbert, Ian H.
Publicado 2012

The role of auxiliary domains in modulating CHD4 activity suggests mechanistic commonality between enzyme families

por Zhong, Yichen, Moghaddas Sani, Hakimeh, Paudel, Bishnu P., Low, Jason K. K., Silva, Ana P. G., Mueller, Stefan, Deshpande, Chandrika, Panjikar, Santosh, Reid, Xavier J., Bedward, Max J., van Oijen, Antoine M., Mackay, Joel P.
Publicado 2022

Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo

por Vickers, Clare F., Silva, Ana P. G., Chakraborty, Ajanta, Fernandez, Paulina, Kurepina, Natalia, Saville, Charis, Naranjo, Yandi, Pons, Miquel, Schnettger, Laura S., Gutierrez, Maximiliano G., Park, Steven, Kreiswith, Barry N., Perlin, David S., Thomas, Eric J., Cavet, Jennifer S., Tabernero, Lydia
Publicado 2018

Cyclic peptides can engage a single binding pocket through highly divergent modes

por Patel, Karishma, Walport, Louise J., Walshe, James L., Solomon, Paul D., Low, Jason K. K., Tran, Daniel H., Mouradian, Kevork S., Silva, Ana P. G., Wilkinson-White, Lorna, Norman, Alexander, Franck, Charlotte, Matthews, Jacqueline M., Guss, J. Mitchell, Payne, Richard J., Passioura, Toby, Suga, Hiroaki, Mackay, Joel P.
Publicado 2020

The Nucleosome Remodeling and Deacetylase Complex Has an Asymmetric, Dynamic, and Modular Architecture

por Low, Jason K.K., Silva, Ana P.G., Tabar, Mehdi Sharifi, Torrado, Mario, Webb, Sarah R., Parker, Benjamin L., Sana, Maryam, Smits, Callum, Schmidberger, Jason W., Brillault, Lou, Jackman, Matthew J., Williams, David C., Blobel, Gerd A., Hake, Sandra B., Shepherd, Nicholas E., Landsberg, Michael J., Mackay, Joel P.
Publicado 2020

Insight into the Architecture of the NuRD Complex: STRUCTURE OF THE RbAp48-MTA1 SUBCOMPLEX

por Alqarni, Saad S. M., Murthy, Andal, Zhang, Wei, Przewloka, Marcin R., Silva, Ana P. G., Watson, Aleksandra A., Lejon, Sara, Pei, Xue Y., Smits, Arne H., Kloet, Susan L., Wang, Hongxin, Shepherd, Nicholas E., Stokes, Philippa H., Blobel, Gerd A., Vermeulen, Michiel, Glover, David M., Mackay, Joel P., Laue, Ernest D.
Publicado 2014