Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175

por Chen, Edwin, Paing, May M., Salinas, Nichole, Sim, B. Kim Lee, Tolia, Niraj H.
Publicado 2013

Controlled human malaria infection (CHMI) outcomes in Kenyan adults is associated with prior history of malaria exposure and anti-schizont antibody response

por Kapulu, Melissa C., Kimani, Domtila, Njuguna, Patricia, Hamaluba, Mainga, Otieno, Edward, Kimathi, Rinter, Tuju, James, Sim, B. Kim Lee
Publicado 2022

Robust, reproducible, industrialized, standard membrane feeding assay for assessing the transmission blocking activity of vaccines and drugs against Plasmodium falciparum

por Li, Tao, Eappen, Abraham G, Richman, Adam M, Billingsley, Peter F, Abebe, Yonas, Li, Minglin, Padilla, Debbie, Rodriguez-Barraquer, Isabel, Sim, B Kim Lee, Hoffman, Stephen L
Publicado 2015

Is Saglin a mosquito salivary gland receptor for Plasmodium falciparum?

por O’Brochta, David A., Alford, Robert, Harrell, Robert, Aluvihare, Channa, Eappen, Abraham G., Li, Tao, Chakravarty, Sumana, Sim, B. Kim Lee, Hoffman, Stephen L., Billingsley, Peter F.
Publicado 2019

Transcriptome profiling reveals functional variation in Plasmodium falciparum parasites from controlled human malaria infection studies

por Hoo, Regina, Bruske, Ellen, Dimonte, Sandra, Zhu, Lei, Mordmüller, Benjamin, Sim, B. Kim Lee, Kremsner, Peter G., Hoffman, Stephen L., Bozdech, Zbynek, Frank, Matthias, Preiser, Peter R.
Publicado 2019

Plasmodium falciparum Malaria Challenge by the Bite of Aseptic Anopheles stephensi Mosquitoes: Results of a Randomized Infectivity Trial

por Lyke, Kirsten E., Laurens, Matthew, Adams, Matthew, Billingsley, Peter F., Richman, Adam, Loyevsky, Mark, Chakravarty, Sumana, Plowe, Christopher V., Sim, B. Kim Lee, Edelman, Robert, Hoffman, Stephen L.
Publicado 2010

Delineation of Stage Specific Expression of Plasmodium falciparum EBA-175 by Biologically Functional Region II Monoclonal Antibodies

por Sim, B. Kim Lee, Narum, David L., Chattopadhyay, Rana, Ahumada, Adriana, Haynes, J. David, Fuhrmann, Steven R., Wingard, Jennifer N., Liang, Hong, Moch, J. Kathleen, Hoffman, Stephen L.
Publicado 2011

Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence

por Inbar, Ehud, Eappen, Abraham G., Alford, Robert T., Reid, William, Harrell, Robert A., Hosseini, Maryam, Chakravarty, Sumana, Li, Tao, Sim, B. Kim Lee, Billingsley, Peter F., Hoffman, Stephen L.
Publicado 2021

Sex-Specific Differences in Cytokine Induction by the Glycolipid Adjuvant 7DW8-5 in Mice

por Watson, Felicia N., Duncombe, Caroline J., Kalata, Anya C., Conrad, Ethan, Chakravarty, Sumana, Sim, B. Kim Lee, Hoffman, Stephen L., Tsuji, Moriya, Shears, Melanie J., Murphy, Sean C.
Publicado 2022

Transient knockdown of Anopheles stephensi LRIM1 using RNAi increases Plasmodium falciparum sporozoite salivary gland infections

por Billingsley, Peter F., George, Kasim I., Eappen, Abraham G., Harrell, Robert A., Alford, Robert, Li, Tao, Chakravarty, Sumana, Sim, B. Kim Lee, Hoffman, Stephen L., O’Brochta, David A.
Publicado 2021

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection

por Scally, Stephen W., Murugan, Rajagopal, Bosch, Alexandre, Triller, Gianna, Costa, Giulia, Mordmüller, Benjamin, Kremsner, Peter G., Sim, B. Kim Lee, Hoffman, Stephen L., Levashina, Elena A., Wardemann, Hedda, Julien, Jean-Philippe
Publicado 2018

Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections

por Bachmann, Anna, Petter, Michaela, Krumkamp, Ralf, Esen, Meral, Held, Jana, Scholz, Judith A. M., Li, Tao, Sim, B. Kim Lee, Hoffman, Stephen L., Kremsner, Peter G., Mordmüller, Benjamin, Duffy, Michael F., Tannich, Egbert
Publicado 2016

A First for Human Vaccinology: GMP Compliant Radiation Attenuation of Plasmodium falciparum Sporozoites for Production of a Vaccine Against Malaria

por James, Eric R., Matheny, Steve, Overby, James, Sim, B. Kim Lee, Eappen, Abraham G., Li, Tao, Li, Ming Lin, Richie, Thomas L., Chakravarty, Sumana, Gunasekera, Anusha, Murshedkar, Tooba, Billingsley, Peter F., Hoffman, Stephen L.
Publicado 2022

Successful Human Infection with P. falciparum Using Three Aseptic Anopheles stephensi Mosquitoes: A New Model for Controlled Human Malaria Infection

por Laurens, Matthew B., Billingsley, Peter, Richman, Adam, Eappen, Abraham G., Adams, Matthew, Li, Tao, Chakravarty, Sumana, Gunasekera, Anusha, Jacob, Christopher G., Sim, B. Kim Lee, Edelman, Robert, Plowe, Christopher V., Hoffman, Stephen L., Lyke, Kirsten E.
Publicado 2013

Plasmodium 18S rRNA of intravenously administered sporozoites does not persist in peripheral blood

por Murphy, Sean C., Ishizuka, Andrew S., Billman, Zachary P., Olsen, Tayla M., Seilie, Annette M., Chang, Ming, Smith, Nahum, Chuenchob, Vorada, Chakravarty, Sumana, Sim, B. Kim Lee, Kappe, Stefan H. I., Hoffman, Stephen L., Seder, Robert A.
Publicado 2018

Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression

por Bachmann, Anna, Bruske, Ellen, Krumkamp, Ralf, Turner, Louise, Wichers, J. Stephan, Petter, Michaela, Held, Jana, Duffy, Michael F., Sim, B. Kim Lee, Hoffman, Stephen L., Kremsner, Peter G., Lell, Bertrand, Lavstsen, Thomas, Frank, Matthias, Mordmüller, Benjamin, Tannich, Egbert
Publicado 2019

Proteome-wide analysis of a malaria vaccine study reveals personalized humoral immune profiles in Tanzanian adults

por Camponovo, Flavia, Campo, Joseph J, Le, Timothy Q, Oberai, Amit, Hung, Christopher, Pablo, Jozelyn V, Teng, Andy A, Liang, Xiaowu, Sim, B Kim Lee, Jongo, Said, Abdulla, Salim, Tanner, Marcel, Hoffman, Stephen L, Daubenberger, Claudia, Penny, Melissa A
Publicado 2020

PfSPZ-CVac efficacy against malaria increases from 0% to 75% when administered in the absence of erythrocyte stage parasitemia: A randomized, placebo-controlled trial with controll...

por Murphy, Sean C., Deye, Gregory A., Sim, B. Kim Lee, Galbiati, Shirley, Kennedy, Jessie K., Cohen, Kristen W., Chakravarty, Sumana, KC, Natasha, Abebe, Yonas, James, Eric R., Kublin, James G., Hoffman, Stephen L., Richie, Thomas L., Jackson, Lisa A.
Publicado 2021

Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa

por Silva, Joana C., Dwivedi, Ankit, Moser, Kara A., Sissoko, Mahamadou S., Epstein, Judith E., Healy, Sara A., Lyke, Kirsten E., Mordmüller, Benjamin, Kremsner, Peter G., Duffy, Patrick E., Murshedkar, Tooba, Sim, B. Kim Lee, Richie, Thomas L., Hoffman, Stephen L.
Publicado 2022

Ultra-low volume intradermal administration of radiation-attenuated sporozoites with the glycolipid adjuvant 7DW8-5 completely protects mice against malaria

por Watson, Felicia N, Shears, Melanie J, Kalata, Anya C, Duncombe, Caroline J, Seilie, A Mariko, Chavtur, Chris, Conrad, Ethan, Talavera, Irene Cruz, Raappana, Andrew, Sather, D Noah, Chakravarty, Sumana, Sim, B Kim Lee, Hoffman, Stephen L, Tsuji, Moriya, Murphy, Sean C
Publicado 2023