Kinetic characterisation of arylamine N-acetyltransferase from Pseudomonas aeruginosa

por Westwood, Isaac M, Sim, Edith
Publicado 2007

Activation of nitrofurazone by azoreductases: multiple activities in one enzyme

por Ryan, Ali, Kaplan, Elise, Laurieri, Nicola, Lowe, Edward, Sim, Edith
Publicado 2011

NAT gene polymorphisms and susceptibility to Alzheimer's disease: identification of a novel NAT1 allelic variant

por Johnson, Nichola, Bell, Peter, Jonovska, Vesna, Budge, Marc, Sim, Edith
Publicado 2004

Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism

por Wakefield, Larissa, Cornish, Valerie, Long, Hilary, Griffiths, William J., Sim, Edith
Publicado 2007

Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system

por Wakefield, Larissa, Cornish, Valerie, Long, Hilary, Kawamura, Akane, Zhang, Xiaoyan, Hein, David W., Sim, Edith
Publicado 2008

Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1

por Kawamura, Akane, Westwood, Isaac, Wakefield, Larissa, Long, Hilary, Zhang, Naixia, Walters, Kylie, Redfield, Christina, Sim, Edith
Publicado 2008

Comparative analysis of xenobiotic metabolising N-acetyltransferases from ten non-human primates as in vitro models of human homologues

por Tsirka, Theodora, Konstantopoulou, Maria, Sabbagh, Audrey, Crouau-Roy, Brigitte, Ryan, Ali, Sim, Edith, Boukouvala, Sotiria, Fakis, Giannoulis
Publicado 2018

Exploration of Piperidinols as Potential Antitubercular Agents

por Abuhammad, Areej, Fullam, Elizabeth, Bhakta, Sanjib, Russell, Angela J., Morris, Garrett M., Finn, Paul W., Sim, Edith
Publicado 2014

Arylamine N-Acetyltransferases in Mycobacteria

por Sim, Edith, Sandy, James, Evangelopoulos, Dimitrios, Fullam, Elizabeth, Bhakta, Sanjib, Westwood, Isaac, Krylova, Anna, Lack, Nathan, Noble, Martin
Publicado 2008

Identification of NAD(P)H Quinone Oxidoreductase Activity in Azoreductases from P. aeruginosa: Azoreductases and NAD(P)H Quinone Oxidoreductases Belong to the Same FMN-Dependent Su...

por Ryan, Ali, Kaplan, Elise, Nebel, Jean-Christophe, Polycarpou, Elena, Crescente, Vincenzo, Lowe, Edward, Preston, Gail M., Sim, Edith
Publicado 2014

Structure of HsaD, a steroid-degrading hydrolase, from Mycobacterium tuberculosis

por Lack, Nathan, Lowe, Edward D., Liu, Jie, Eltis, Lindsay D., Noble, Martin E. M., Sim, Edith, Westwood, Isaac M.
Publicado 2007

Differences between murine arylamine N-acetyltransferase type 1 and human arylamine N-acetyltransferase type 2 defined by substrate specificity and inhibitor binding

por Laurieri, Nicola, Kawamura, Akane, Westwood, Isaac M, Varney, Amy, Morris, Elizabeth, Russell, Angela J, Stanley, Lesley A, Sim, Edith
Publicado 2014

Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis

por Evangelopoulos, Dimitrios, Gupta, Antima, Lack, Nathan A., Maitra, Arundhati, ten Bokum, Annemieke M.C., Kendall, Sharon, Sim, Edith, Bhakta, Sanjib
Publicado 2014

Homologues of xenobiotic metabolizing N-acetyltransferases in plant-associated fungi: Novel functions for an old enzyme family

por Karagianni, Eleni P., Kontomina, Evanthia, Davis, Britton, Kotseli, Barbara, Tsirka, Theodora, Garefalaki, Vasiliki, Sim, Edith, Glenn, Anthony E., Boukouvala, Sotiria
Publicado 2015

From Arylamine N-Acetyltransferase to Folate-Dependent Acetyl CoA Hydrolase: Impact of Folic Acid on the Activity of (HUMAN)NAT1 and Its Homologue (MOUSE)NAT2

por Laurieri, Nicola, Dairou, Julien, Egleton, James E., Stanley, Lesley A., Russell, Angela J., Dupret, Jean-Marie, Sim, Edith, Rodrigues-Lima, Fernando
Publicado 2014

Gene expression profiling of primary male breast cancers reveals two unique subgroups and identifies N-acetyltransferase-1 (NAT1) as a novel prognostic biomarker

por Johansson, Ida, Nilsson, Cecilia, Berglund, Pontus, Lauss, Martin, Ringnér, Markus, Olsson, Håkan, Luts, Lena, Sim, Edith, Thorstensson, Sten, Fjällskog, Marie-Louise, Hedenfalk, Ingrid
Publicado 2012

Arylamine N-Acetyltransferase Is Required for Synthesis of Mycolic Acids and Complex Lipids in Mycobacterium bovis BCG and Represents a Novel Drug Target

por Bhakta, Sanjib, Besra, Gurdyal S., Upton, Anna M., Parish, Tanya, Sholto-Douglas-Vernon, Carolyn, Gibson, Kevin J.C., Knutton, Stuart, Gordon, Siamon, daSilva, Rosangela P., Anderton, Matthew C., Sim, Edith
Publicado 2004

A Novel Color Change Mechanism for Breast Cancer Biomarker Detection: Naphthoquinones as Specific Ligands of Human Arylamine N-Acetyltransferase 1

por Laurieri, Nicola, Egleton, James E., Varney, Amy, Thinnes, Cyrille C., Quevedo, Camilo E., Seden, Peter T., Thompson, Sam, Rodrigues-Lima, Fernando, Dairou, Julien, Dupret, Jean-Marie, Russell, Angela J., Sim, Edith
Publicado 2013

Piperidinols That Show Anti-Tubercular Activity as Inhibitors of Arylamine N-Acetyltransferase: An Essential Enzyme for Mycobacterial Survival Inside Macrophages

por Abuhammad, Areej, Fullam, Elizabeth, Lowe, Edward D., Staunton, David, Kawamura, Akane, Westwood, Isaac M., Bhakta, Sanjib, Garner, Alun Christopher, Wilson, David L., Seden, Peter T., Davies, Stephen G., Russell, Angela J., Garman, Elspeth F., Sim, Edith
Publicado 2012

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway

por Fineran, Paul, Lloyd-Evans, Emyr, Lack, Nathan A., Platt, Nick, Davis, Lianne C., Morgan, Anthony J., Höglinger, Doris, Tatituri, Raju Venkata V., Clark, Simon, Williams, Ian M., Tynan, Patricia, Al Eisa, Nada, Nazarova, Evgeniya, Williams, Ann, Galione, Antony, Ory, Daniel S., Besra, Gurdyal S., Russell, David G., Brenner, Michael B., Sim, Edith, Platt, Frances M.
Publicado 2017