Drug resistance in targeted cancer therapies with RAF inhibitors

por Degirmenci, Ufuk, Yap, Jiajun, Sim, Yuen Rong M., Qin, Shiru, Hu, Jiancheng
Publicado 2021

The stability of R-spine defines RAF inhibitor resistance: A comprehensive analysis of oncogenic BRAF mutants with in-frame insertion of αC-β4 loop

por Yap, Jiajun, Deepak, R. N. V. Krishna, Tian, Zizi, Ng, Wan Hwa, Goh, Kah Chun, Foo, Alicia, Tee, Zi Heng, Mohanam, Manju Payini, Sim, Yuen Rong M., Degirmenci, Ufuk, Lam, Paula, Chen, Zhongzhou, Fan, Hao, Hu, Jiancheng
Publicado 2021

BRAF(V600E) mutation together with loss of Trp53 or pTEN drives the origination of hairy cell leukemia from B-lymphocytes

por Yap, Jiajun, Yuan, Jimin, Ng, Wan Hwa, Chen, Gao Bin, Sim, Yuen Rong M., Goh, Kah Chun, Teo, Joey, Lim, Trixie Y. H., Goay, Shee Min, Teo, Jia Hao Jackie, Lao, Zhentang, Lam, Paula, Sabapathy, Kanaga, Hu, Jiancheng
Publicado 2023