A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency

por Simard, Marie‐Lune, Mourier, Arnaud, Greaves, Laura C, Taylor, Robert W, Stewart, James B
Publicado 2018

Dynamics of neuroinflammation in the macrosphere model of arterio-arterial embolic focal ischemia: an approximation to human stroke patterns

por Walberer, Maureen, Rueger, Maria A, Simard, Marie-Lune, Emig, Beata, Jander, Sebastian, Fink, Gereon R, Schroeter, Michael
Publicado 2010

A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease

por Kauppila, Johanna H.K., Baines, Holly L., Bratic, Ana, Simard, Marie-Lune, Freyer, Christoph, Mourier, Arnaud, Stamp, Craig, Filograna, Roberta, Larsson, Nils-Göran, Greaves, Laura C., Stewart, James B.
Publicado 2016

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria

por Matic, Stanka, Jiang, Min, Nicholls, Thomas J., Uhler, Jay P., Dirksen-Schwanenland, Caren, Polosa, Paola Loguercio, Simard, Marie-Lune, Li, Xinping, Atanassov, Ilian, Rackham, Oliver, Filipovska, Aleksandra, Stewart, James B., Falkenberg, Maria, Larsson, Nils-Göran, Milenkovic, Dusanka
Publicado 2018

Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction

por Milenkovic, Dusanka, Sanz-Moreno, Adrián, Calzada-Wack, Julia, Rathkolb, Birgit, Veronica Amarie, Oana, Gerlini, Raffaele, Aguilar-Pimentel, Antonio, Misic, Jelena, Simard, Marie-Lune, Wolf, Eckhard, Fuchs, Helmut, Gailus-Durner, Valerie, de Angelis, Martin Hrabě, Larsson, Nils-Göran
Publicado 2022

Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo

por Gammage, Payam A., Viscomi, Carlo, Simard, Marie-Lune, Costa, Ana S.H., Gaude, Edoardo, Powell, Christopher A., Van Haute, Lindsey, McCann, Beverly J., Rebelo-Guiomar, Pedro, Cerutti, Raffaele, Zhang, Lei, Rebar, Edward J., Zeviani, Massimo, Frezza, Christian, Stewart, James B., Minczuk, Michal
Publicado 2018