Methods for Activity Analysis of the Proteins that Regulate Histone Methylation

por Quinn, Amy M, Simeonov, Anton
Publicado 2011

Differential Scanning Fluorometry Signatures as Indicators of Enzyme Inhibitor Mode of Action: Case Study of Glutathione S-Transferase

por Lea, Wendy A., Simeonov, Anton
Publicado 2012

Drug repurposing screens and synergistic drug‐combinations for infectious diseases

por Zheng, Wei, Sun, Wei, Simeonov, Anton
Publicado 2017

Editorial: Biophysical target engagement assays in chemical biology and pharmacological research

por Baljinnyam, Bolormaa, Coussens, Nathan P., Simeonov, Anton
Publicado 2023

Fruitful Neutralizing Antibody Pipeline Brings Hope To Defeat SARS-Cov-2

por Renn, Alex, Fu, Ying, Hu, Xin, Hall, Matthew D., Simeonov, Anton
Publicado 2020

Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity

por Dorjsuren, Dorjbal, Kim, Daemyung, Maloney, David J., Wilson, David M., Simeonov, Anton
Publicado 2011

High-Throughput 1,536-Well Fluorescence Polarization Assays for α(1)-Acid Glycoprotein and Human Serum Albumin Binding

por Yasgar, Adam, Furdas, Silviya D., Maloney, David J., Jadhav, Ajit, Jung, Manfred, Simeonov, Anton
Publicado 2012

Bioactivity Signatures of Drugs vs. Environmental Chemicals Revealed by Tox21 High-Throughput Screening Assays

por Ngan, Deborah K., Ye, Lin, Wu, Leihong, Xia, Menghang, Rossoshek, Anna, Simeonov, Anton, Huang, Ruili
Publicado 2019

A systems approach to enable effective team science from the internal research program of the National Center for Advancing Translational Sciences

por Vogel, Amanda L., Knebel, Ann R., Faupel-Badger, Jessica M., Portilla, Lili M., Simeonov, Anton
Publicado 2021

A homogeneous method for investigation of methylation-dependent protein–protein interactions in epigenetics

por Quinn, Amy M., Bedford, Mark T., Espejo, Alexsandra, Spannhoff, Astrid, Austin, Christopher P., Oppermann, Udo, Simeonov, Anton
Publicado 2010

Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19

por Eastman, Richard T., Roth, Jacob S., Brimacombe, Kyle R., Simeonov, Anton, Shen, Min, Patnaik, Samarjit, Hall, Matthew D.
Publicado 2020

Correction to Remdesivir: A Review of Its Discovery and Development Leading to Human Clinical Trials for Treatment of COVID-19

por Eastman, Richard T., Roth, Jacob S., Brimacombe, Kyle R., Simeonov, Anton, Shen, Min, Patnaik, Samarjit, Hall, Matthew D.
Publicado 2020

An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19

por Shrimp, Jonathan H., Kales, Stephen C., Sanderson, Philip E., Simeonov, Anton, Shen, Min, Hall, Matthew D.
Publicado 2020

A High-Throughput Approach for Identification of Novel General Anesthetics

por Lea, Wendy A., Xi, Jin, Jadhav, Ajit, Lu, Louis, Austin, Christopher P., Simeonov, Anton, Eckenhoff, Roderic G.
Publicado 2009

Diverse Small Molecule Inhibitors of Human Apurinic/Apyrimidinic Endonuclease APE1 Identified from a Screen of a Large Public Collection

por Dorjsuren, Dorjbal, Kim, Daemyung, Vyjayanti, Vaddadi N., Maloney, David J., Jadhav, Ajit, Wilson, David M., Simeonov, Anton
Publicado 2012

Identification of hit compounds with anti-schistosomal activity on in vitro generated juvenile worms in cell-free medium

por Vejzagić, Nermina, Prodjinotho, Ulrich Fabien, El-Khafif, Nagwa, Huang, Ruili, Simeonov, Anton, Spangenberg, Thomas, Prazeres da Costa, Clarissa
Publicado 2021

Application of temperature-responsive HIS-tag fluorophores to differential scanning fluorimetry screening of small molecule libraries

por Ronzetti, Michael H., Baljinnyam, Bolormaa, Itkin, Zina, Jain, Sankalp, Rai, Ganesha, Zakharov, Alexey V., Pal, Utpal, Simeonov, Anton
Publicado 2022

A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ

por Yamanaka, Kinrin, Dorjsuren, Dorjbal, Eoff, Robert L., Egli, Martin, Maloney, David J., Jadhav, Ajit, Simeonov, Anton, Lloyd, R. Stephen
Publicado 2012

Expanding biological space coverage enhances the prediction of drug adverse effects in human using in vitro activity profiles

por Huang, Ruili, Xia, Menghang, Sakamuru, Srilatha, Zhao, Jinghua, Lynch, Caitlin, Zhao, Tongan, Zhu, Hu, Austin, Christopher P., Simeonov, Anton
Publicado 2018

Identification and Characterization of Inhibitors of Human Apurinic/apyrimidinic Endonuclease APE1

por Simeonov, Anton, Kulkarni, Avanti, Dorjsuren, Dorjbal, Jadhav, Ajit, Shen, Min, McNeill, Daniel R., Austin, Christopher P., Wilson, David M.
Publicado 2009