Increased Frequency and Compromised Function of T Regulatory Cells in Systemic Sclerosis (SSc) Is Related to a Diminished CD69 and TGFβ Expression

por Radstake, Timothy R. D. J., van Bon, Lenny, Broen, Jasper, Wenink, Mark, Santegoets, Kim, Deng, Yanhui, Hussaini, Anila, Simms, Robert, Cruikshank, William W., Lafyatis, Robert
Publicado 2009

Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis

por Rice, Lisa M., Mantero, Julio C., Stratton, Eric A., Warburton, Rod, Roberts, Kari, Hill, Nicholas, Simms, Robert W., Domsic, Robyn, Farber, Harrison W., Layfatis, Robert
Publicado 2018

Correction: Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis

por Rice, Lisa M., Mantero, Julio C., Stratton, Eric A., Warburton, Rod, Roberts, Kari, Hill, Nicholas, Simms, Robert W., Domsic, Robyn, Farber, Harrison W., Lafyatis, Robert
Publicado 2022

Dose-escalation of human anti-interferon-α receptor monoclonal antibody MEDI-546 in subjects with systemic sclerosis: a phase 1, multicenter, open label study

por Goldberg, Avram, Geppert, Thomas, Schiopu, Elena, Frech, Tracy, Hsu, Vivien, Simms, Robert W, Peng, Stanford L, Yao, Yihong, Elgeioushi, Nairouz, Chang, Linda, Wang, Bing, Yoo, Stephen
Publicado 2014

Microbiome dysbiosis is associated with disease duration and increased inflammatory gene expression in systemic sclerosis skin

por Johnson, Michael E., Franks, Jennifer M., Cai, Guoshuai, Mehta, Bhaven K., Wood, Tammara A., Archambault, Kimberly, Pioli, Patricia A., Simms, Robert W., Orzechowski, Nicole, Arron, Sarah, Whitfield, Michael L.
Publicado 2019

Results of a phase-I/II randomized, masked, placebo-controlled trial of recombinant human interleukin-11 (rhIL-11) in the treatment of subjects with active rheumatoid arthritis

por Moreland, Larry, Gugliotti, Ron, King, Kevin, Chase, Walter, Weisman, Michael, Greco, Thomas, Fife, Rose, Korn, Joseph, Simms, Robert, Tesser, John, Hillson, Jan, Caldwell, Jacques, Schnitzer, Thomas, Lyons, David, Schwertschlag, Ullrich
Publicado 2001

Safety and Efficacy of Lenabasum in a Phase II, Randomized, Placebo‐Controlled Trial in Adults With Systemic Sclerosis

por Spiera, Robert, Hummers, Laura, Chung, Lorinda, Frech, Tracy M., Domsic, Robyn, Hsu, Vivien, Furst, Daniel E., Gordon, Jessica, Mayes, Maureen, Simms, Robert, Lafyatis, Robert, Martyanov, Viktor, Wood, Tammara, Whitfield, Michael L., Constantine, Scott, Lee, Elizabeth, Dgetluck, Nancy, White, Barbara
Publicado 2020

Adipose‐Derived Regenerative Cell Transplantation for the Treatment of Hand Dysfunction in Systemic Sclerosis: A Randomized Clinical Trial

por Khanna, Dinesh, Caldron, Paul, Martin, Richard W., Kafaja, Suzanne, Spiera, Robert, Shahouri, Shadi, Shah, Ankoor, Hsu, Vivien, Ervin, John, Simms, Robert, Domsic, Robyn T., Steen, Virginia, Hummers, Laura K., Derk, Chris, Mayes, Maureen, Chatterjee, Soumya, Varga, John, Kesten, Steven, Fraser, John K., Furst, Daniel E.
Publicado 2022

miR-155 in the progression of lung fibrosis in systemic sclerosis

por Christmann, Romy B., Wooten, Alicia, Sampaio-Barros, Percival, Borges, Claudia L., Carvalho, Carlos R. R., Kairalla, Ronaldo A., Feghali-Bostwick, Carol, Ziemek, Jessica, Mei, Yu, Goummih, Salma, Tan, Jiangning, Alvarez, Diana, Kass, Daniel J., Rojas, Mauricio, de Mattos, Thiago Lemos, Parra, Edwin, Stifano, Giuseppina, Capelozzi, Vera L., Simms, Robert W., Lafyatis, Robert
Publicado 2016

Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations

por Gorlova, Olga Y., Li, Yafang, Gorlov, Ivan, Ying, Jun, Chen, Wei V., Assassi, Shervin, Reveille, John D., Arnett, Frank C., Zhou, Xiaodong, Bossini-Castillo, Lara, Lopez-Isac, Elena, Acosta-Herrera, Marialbert, Gregersen, Peter K., Lee, Annette T., Steen, Virginia D., Fessler, Barri J., Khanna, Dinesh, Schiopu, Elena, Silver, Richard M., Molitor, Jerry A., Furst, Daniel E., Kafaja, Suzanne, Simms, Robert W., Lafyatis, Robert A., Carreira, Patricia, Simeon, Carmen Pilar, Castellvi, Ivan, Beltran, Emma, Ortego, Norberto, Amos, Christopher I., Martin, Javier, Mayes, Maureen D.
Publicado 2018

Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: a case control study in Caucasian patients

por Wu, Minghua, Assassi, Shervin, Salazar, Gloria A., Pedroza, Claudia, Gorlova, Olga Y., Chen, Wei V., Charles, Julio, Taing, Miranda L., Liao, Kelley, Wigley, Fredrick M., Hummers, Laura K., Shah, Ami A., Hinchcliff, Monique, Khanna, Dinesh, Schiopu, Elena, Phillips, Kristine, Furst, Daniel E., Steen, Virginia, Baron, Murray, Hudson, Marie, Zhou, Xiaodong, Pope, Janet, Jones, Niall, Docherty, Peter, Khalidi, Nader A., Robinson, David, Simms, Robert W., Silver, Richard M., Frech, Tracy M., Fessler, Barri J., Fritzler, Marvin J., Molitor, Jerry A., Segal, Barbara M., Movahedian, Malahat, Martín, Javier, Varga, John, Mayes, Maureen D.
Publicado 2016

Mycophenolate Mofetil versus Oral Cyclophosphamide in Scleroderma-related Interstitial Lung Disease: Scleroderma Lung Study II (SLS-II), a double-blind, parallel group, randomised...

por Tashkin, Donald P, Roth, Michael D, Clements, Philip J, Furst, Daniel E, Khanna, Dinesh, Kleerup, Eric C, Goldin, Jonathan, Arriola, Edgar, Volkmann, Elizabeth R, Kafaja, Suzanne, Silver, Richard, Steen, Virginia, Strange, Charlie, Wise, Robert, Wigley, Fredrick, Mayes, Maureen, Riley, David J, Hussain, Sabiha, Assassi, Shervin, Hsu, Vivien M, Patel, Bela, Phillips, Kristine, Martinez, Fernando, Golden, Jeffrey, Connolly, M Kari, Varga, John, Dematte, Jane, Hinchcliff, Monique, Fischer, Aryeh, Swigris, Jeffrey, Meehan, Richard, Theodore, Arthur, Simms, Robert, Volkov, Suncica, Schraufnagel, Dean E, Scholand, Mary Beth, Frech, Tracy, Molitor, Jerry A, Highland, Kristin, Read, Charles A, Fritzler, Marvin J, Kim, Grace Hyun J, Tseng, Chi-Hong, Elashoff, Robert M
Publicado 2016

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

por Rhodes, Christopher J, Batai, Ken, Bleda, Marta, Haimel, Matthias, Southgate, Laura, Germain, Marine, Pauciulo, Michael W, Hadinnapola, Charaka, Aman, Jurjan, Girerd, Barbara, Arora, Amit, Knight, Jo, Hanscombe, Ken B, Karnes, Jason H, Kaakinen, Marika, Gall, Henning, Ulrich, Anna, Harbaum, Lars, Cebola, Inês, Ferrer, Jorge, Lutz, Katie, Swietlik, Emilia M, Ahmad, Ferhaan, Amouyel, Philippe, Archer, Stephen L, Argula, Rahul, Austin, Eric D, Badesch, David, Bakshi, Sahil, Barnett, Christopher, Benza, Raymond, Bhatt, Nitin, Bogaard, Harm J, Burger, Charles D, Chakinala, Murali, Church, Colin, Coghlan, John G, Condliffe, Robin, Corris, Paul A, Danesino, Cesare, Debette, Stéphanie, Elliott, C Gregory, Elwing, Jean, Eyries, Melanie, Fortin, Terry, Franke, Andre, Frantz, Robert P, Frost, Adaani, Garcia, Joe G N, Ghio, Stefano, Ghofrani, Hossein-Ardeschir, Gibbs, J Simon R, Harley, John, He, Hua, Hill, Nicholas S, Hirsch, Russel, Houweling, Arjan C, Howard, Luke S, Ivy, Dunbar, Kiely, David G, Klinger, James, Kovacs, Gabor, Lahm, Tim, Laudes, Matthias, Machado, Rajiv D, MacKenzie Ross, Robert V, Marsolo, Keith, Martin, Lisa J, Moledina, Shahin, Montani, David, Nathan, Steven D, Newnham, Michael, Olschewski, Andrea, Olschewski, Horst, Oudiz, Ronald J, Ouwehand, Willem H, Peacock, Andrew J, Pepke-Zaba, Joanna, Rehman, Zia, Robbins, Ivan, Roden, Dan M, Rosenzweig, Erika B, Saydain, Ghulam, Scelsi, Laura, Schilz, Robert, Seeger, Werner, Shaffer, Christian M, Simms, Robert W, Simon, Marc, Sitbon, Olivier, Suntharalingam, Jay, Tang, Haiyang, Tchourbanov, Alexander Y, Thenappan, Thenappan, Torres, Fernando, Toshner, Mark R, Treacy, Carmen M, Vonk Noordegraaf, Anton, Waisfisz, Quinten, Walsworth, Anna K, Walter, Robert E, Wharton, John, White, R James, Wilt, Jeffrey, Wort, Stephen J, Yung, Delphine, Lawrie, Allan, Humbert, Marc, Soubrier, Florent, Trégouët, David-Alexandre, Prokopenko, Inga, Kittles, Richard, Gräf, Stefan, Nichols, William C, Trembath, Richard C, Desai, Ankit A, Morrell, Nicholas W, Wilkins, Martin R
Publicado 2019