A Transversal Approach Combining In Silico, In Vitro and In Vivo Models to Describe the Metabolism of the Receptor Interacting Protein 1 Kinase Inhibitor Sibiriline

por Pelletier, Romain, Gicquel, Thomas, Simoes Eugenio, Mélanie, Ferron, Pierre-Jean, Morel, Isabelle, Delehouzé, Claire, Dimanche-Boitrel, Marie-Thérèse, Rousselot, Morgane, Le Daré, Brendan
Publicado 2022

Hepatocellular Carcinoma Emergence in Diabetic Mice with Non-Alcoholic Steatohepatitis Depends on Diet and Is Delayed in Liver Exhibiting an Active Immune Response

por Simoes Eugénio, Mélanie, Farooq, Muhammad, Dion, Sarah, Devisme, Christelle, Raguenes-Nicol, Céline, Piquet-Pellorce, Claire, Samson, Michel, Dimanche-Boitrel, Marie-Thérèse, Le Seyec, Jacques
Publicado 2020

Depletion of RIPK1 in hepatocytes exacerbates liver damage in fulminant viral hepatitis

por Farooq, Muhammad, Filliol, Aveline, Simoes Eugénio, Mélanie, Piquet-Pellorce, Claire, Dion, Sarah, Raguenes-Nicol, Céline, Jan, Aurélien, Dimanche-Boitrel, Marie-Thérèse, Le Seyec, Jacques, Samson, Michel
Publicado 2019

TRIM21, a New Component of the TRAIL-Induced Endogenous Necrosome Complex

por Simoes Eugénio, Mélanie, Faurez, Florence, Kara-Ali, Ghania H., Lagarrigue, Mélanie, Uhart, Perrine, Bonnet, Marion C., Gallais, Isabelle, Com, Emmanuelle, Pineau, Charles, Samson, Michel, Le Seyec, Jacques, Dimanche-Boitrel, Marie-Thérèse
Publicado 2021

Betulin, a Newly Characterized Compound in Acacia auriculiformis Bark, Is a Multi-Target Protein Kinase Inhibitor

por Ahmadu, Augustine A., Delehouzé, Claire, Haruna, Anas, Mustapha, Lukman, Lawal, Bilqis A., Udobre, Aniefiok, Baratte, Blandine, Triscornia, Camilla, Autret, Axelle, Robert, Thomas, Bulinski, Jeannette Chloë, Rousselot, Morgane, Simoes Eugénio, Mélanie, Dimanche-Boitrel, Marie-Thérèse, Petzer, Jacobus P., Legoabe, Lesetja J., Bach, Stéphane
Publicado 2021