Autophagy takes it all – autophagy inducers target immune aging

por Zinecker, Heidi, Simon, Anna Katharina
Publicado 2022

Autophagy in the immune system

por Puleston, Daniel J, Simon, Anna Katharina
Publicado 2014

In aged primary T cells, mitochondrial stress contributes to telomere attrition measured by a novel imaging flow cytometry assay

por Sanderson, Sharon Lesley, Simon, Anna Katharina
Publicado 2017

Autophagy orchestrates the crosstalk between cells and organs

por Piletic, Klara, Alsaleh, Ghada, Simon, Anna Katharina
Publicado 2023

Hallmarks and detection techniques of cellular senescence and cellular ageing in immune cells

por Zhou, Dingxi, Borsa, Mariana, Simon, Anna Katharina
Publicado 2021

Tightrope act: autophagy in stem cell renewal, differentiation, proliferation, and aging

por Phadwal, Kanchan, Watson, Alexander Scarth, Simon, Anna Katharina
Publicado 2012

Autophagy dictates metabolism and differentiation of inflammatory immune cells

por Riffelmacher, Thomas, Richter, Felix Clemens, Simon, Anna Katharina
Publicado 2017

Local exchange of metabolites shapes immunity

por Richter, Felix Clemens, Obba, Sandrine, Simon, Anna Katharina
Publicado 2018

The central role of DNA damage in immunosenescence

por Kell, Loren, Simon, Anna Katharina, Alsaleh, Ghada, Cox, Lynne S.
Publicado 2023

B1a B cells require autophagy for metabolic homeostasis and self-renewal

por Clarke, Alexander J., Riffelmacher, Thomas, Braas, Daniel, Cornall, Richard J., Simon, Anna Katharina
Publicado 2018

Regulatory T cells inhibit Fas ligand-induced innate and adaptive tumour immunity

por Simon, Anna Katharina, Jones, Emma, Richards, Hannah, Wright, Kate, Betts, Gareth, Godkin, Andrew, Screaton, Gavin, Gallimore, Awen
Publicado 2007

The Immune Response to Melanoma Is Limited by Thymic Selection of Self-Antigens

por Träger, Ulrike, Sierro, Sophie, Djordjevic, Gordana, Bouzo, Basma, Khandwala, Shivani, Meloni, Antonella, Mortensen, Monika, Simon, Anna Katharina
Publicado 2012

Autophagy is activated in systemic lupus erythematosus and required for plasmablast development

por Clarke, Alexander J, Ellinghaus, Ursula, Cortini, Andrea, Stranks, Amanda, Simon, Anna Katharina, Botto, Marina, Vyse, Timothy J
Publicado 2015

Autophagy in T cells from aged donors is maintained by spermidine and correlates with function and vaccine responses

por Alsaleh, Ghada, Panse, Isabel, Swadling, Leo, Zhang, Hanlin, Richter, Felix Clemens, Meyer, Alain, Lord, Janet, Barnes, Eleanor, Klenerman, Paul, Green, Christopher, Simon, Anna Katharina
Publicado 2020

A novel method for autophagy detection in primary cells: Impaired levels of macroautophagy in immunosenescent T cells

por Phadwal, Kanchan, Alegre-Abarrategui, Javier, Watson, Alexander Scarth, Pike, Luke, Anbalagan, Selvakumar, Hammond, Ester M., Wade-Martins, Richard, McMichael, Andrew, Klenerman, Paul, Simon, Anna Katharina
Publicado 2012

Autophagy is a critical regulator of memory CD8(+) T cell formation

por Puleston, Daniel J, Zhang, Hanlin, Powell, Timothy J, Lipina, Elina, Sims, Stuart, Panse, Isabel, Watson, Alexander S, Cerundolo, Vincenzo, Townsend, Alain RM, Klenerman, Paul, Simon, Anna Katharina
Publicado 2014

Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy

por Jabir, Majid Sakhi, Hopkins, Lee, Ritchie, Neil D., Ullah, Ihsan, Bayes, Hannah K., Li, Dong, Tourlomousis, Panagiotis, Lupton, Alison, Puleston, Daniel, Simon, Anna Katharina, Bryant, Clare, Evans, Thomas J.
Publicado 2015

Mapping autophagosome contents identifies interleukin-7 receptor-α as a key cargo modulating CD4+ T cell proliferation

por Zhou, Dingxi, Borsa, Mariana, Puleston, Daniel J., Zellner, Susanne, Capera, Jesusa, Sanderson, Sharon, Schifferer, Martina, Hester, Svenja S., Ge, Xin, Fischer, Roman, Jostins, Luke, Behrends, Christian, Alsaleh, Ghada, Simon, Anna Katharina
Publicado 2022

The autophagy protein Atg7 is essential for hematopoietic stem cell maintenance

por Mortensen, Monika, Soilleux, Elizabeth J., Djordjevic, Gordana, Tripp, Rebecca, Lutteropp, Michael, Sadighi-Akha, Elham, Stranks, Amanda J., Glanville, Julie, Knight, Samantha, W. Jacobsen, Sten-Eirik, Kranc, Kamil R., Simon, Anna Katharina
Publicado 2011

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells

por Smith, Amy M., Depp, Constanze, Ryan, Brent J., Johnston, Geoffrey I., Alegre‐Abarrategui, Javier, Evetts, Samuel, Rolinski, Michal, Baig, Fahd, Ruffmann, Claudio, Simon, Anna Katharina, Hu, Michele T. M., Wade‐Martins, Richard
Publicado 2018