Computational Docking of Antibody-Antigen Complexes, Opportunities and Pitfalls Illustrated by Influenza Hemagglutinin

por Pedotti, Mattia, Simonelli, Luca, Livoti, Elsa, Varani, Luca
Publicado 2011

Development of a Novel Bioinformatics Tool for In Silico Validation of Protein Interactions

por Barbarini, Nicola, Simonelli, Luca, Azzalin, Alberto, Comincini, Sergio, Bellazzi, Riccardo
Publicado 2010

Rational engineering of the lccβ T. versicolor laccase for the mediator-less oxidation of large polycyclic aromatic hydrocarbons

por Chiadò, Alessandro, Bosco, Francesca, Bardelli, Marco, Simonelli, Luca, Pedotti, Mattia, Marmo, Luca, Varani, Luca
Publicado 2021

Rational Engineering of a Human Anti-Dengue Antibody through Experimentally Validated Computational Docking

por Simonelli, Luca, Pedotti, Mattia, Beltramello, Martina, Livoti, Elsa, Calzolai, Luigi, Sallusto, Federica, Lanzavecchia, Antonio, Varani, Luca
Publicado 2013

Rational Modification of Estrogen Receptor by Combination of Computational and Experimental Analysis

por Ferrero, Valentina Elisabetta Viviana, Pedotti, Mattia, Chiadò, Alessandro, Simonelli, Luca, Calzolai, Luigi, Varani, Luca, Lettieri, Teresa
Publicado 2014

Altered Cellular Distribution and Sub-Cellular Sorting of Doppel (Dpl) Protein in Human Astrocytoma Cell Lines

por Sbalchiero, Elena, Azzalin, Alberto, Palumbo, Silvia, Barbieri, Giulia, Arias, Agustina, Simonelli, Luca, Ferretti, Luca, Comincini, Sergio
Publicado 2008

Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer

por Guerrini, Giuditta, Mehn, Dora, Fumagalli, Francesco, Gioria, Sabrina, Pedotti, Mattia, Simonelli, Luca, Bianchini, Filippo, Robbiani, Davide F., Varani, Luca, Calzolai, Luigi
Publicado 2023

A bispecific immunotweezer prevents soluble PrP oligomers and abolishes prion toxicity

por Bardelli, Marco, Frontzek, Karl, Simonelli, Luca, Hornemann, Simone, Pedotti, Mattia, Mazzola, Federica, Carta, Manfredi, Eckhardt, Valeria, D’Antuono, Rocco, Virgilio, Tommaso, González, Santiago F., Aguzzi, Adriano, Varani, Luca
Publicado 2018

Adapting Neutralizing Antibodies to Viral Variants by Structure‐Guided Affinity Maturation Using Phage Display Technology

por Peissert, Frederik, Pedotti, Mattia, Corbellari, Riccardo, Simonelli, Luca, De Gasparo, Raoul, Tamagnini, Elia, Plüss, Louis, Elsayed, Abdullah, Matasci, Mattia, De Luca, Roberto, Cassaniti, Irene, Sammartino, Jose’ Camilla, Piralla, Antonio, Baldanti, Fausto, Neri, Dario, Varani, Luca
Publicado 2023

Humoral and cell-mediated response against SARS-CoV-2 variants elicited by mRNA vaccine BNT162b2 in healthcare workers: a longitudinal observational study

por Cassaniti, Irene, Bergami, Federica, Percivalle, Elena, Gabanti, Elisa, Sammartino, Josè Camilla, Ferrari, Alessandro, Adzasehoun, Kodjo Messan Guy, Zavaglio, Federica, Zelini, Paola, Comolli, Giuditta, Sarasini, Antonella, Piralla, Antonio, Ricciardi, Alessandra, Zuccaro, Valentina, Maggi, Fabrizio, Novazzi, Federica, Simonelli, Luca, Varani, Luca, Lilleri, Daniele, Baldanti, Fausto
Publicado 2022

A conformational switch controlling the toxicity of the prion protein

por Frontzek, Karl, Bardelli, Marco, Senatore, Assunta, Henzi, Anna, Reimann, Regina R., Bedir, Seden, Marino, Marika, Hussain, Rohanah, Jurt, Simon, Meisl, Georg, Pedotti, Mattia, Mazzola, Federica, Siligardi, Giuliano, Zerbe, Oliver, Losa, Marco, Knowles, Tuomas, Lakkaraju, Asvin, Zhu, Caihong, Schwarz, Petra, Hornemann, Simone, Holt, Matthew G., Simonelli, Luca, Varani, Luca, Aguzzi, Adriano
Publicado 2022

19n01, a broadly neutralizing antibody against omicron BA.1, BA.2, BA.4/5, and other SARS-CoV-2 variants of concern

por García-Vega, Melissa, Melgoza-González, Edgar A., Hernández-Valenzuela, Sofía, Hinojosa-Trujillo, Diana, Reséndiz-Sandoval, Mónica, Llamas-Covarrubias, Mara Anais, Loza-López, Martín, Valenzuela, Olivia, Soto-Gaxiola, Alan, Hernández-Oñate, Miguel A., Mata-Haro, Verónica, Cassaniti, Irene, Sammartino, Josè Camilla, Ferrari, Alessandro, Simonelli, Luca, Pedotti, Mattia, Sun, Rui, Zuo, Fanglei, Baldanti, Fausto, Varani, Luca, Marcotte, Harold, Pan-Hammarström, Qiang, Hernández, Jesús
Publicado 2023

SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface

por Bertoglio, Federico, Meier, Doris, Langreder, Nora, Steinke, Stephan, Rand, Ulfert, Simonelli, Luca, Heine, Philip Alexander, Ballmann, Rico, Schneider, Kai-Thomas, Roth, Kristian Daniel Ralph, Ruschig, Maximilian, Riese, Peggy, Eschke, Kathrin, Kim, Yeonsu, Schäckermann, Dorina, Pedotti, Mattia, Kuhn, Philipp, Zock-Emmenthal, Susanne, Wöhrle, Johannes, Kilb, Normann, Herz, Tobias, Becker, Marlies, Grasshoff, Martina, Wenzel, Esther Veronika, Russo, Giulio, Kröger, Andrea, Brunotte, Linda, Ludwig, Stephan, Fühner, Viola, Krämer, Stefan Daniel, Dübel, Stefan, Varani, Luca, Roth, Günter, Čičin-Šain, Luka, Schubert, Maren, Hust, Michael
Publicado 2021

Human neutralizing antibodies to cold linear epitopes and to subdomain 1 of SARS-CoV-2

por Bianchini, Filippo, Crivelli, Virginia, Abernathy, Morgan E., Guerra, Concetta, Palus, Martin, Muri, Jonathan, Marcotte, Harold, Piralla, Antonio, Pedotti, Mattia, De Gasparo, Raoul, Simonelli, Luca, Matkovic, Milos, Toscano, Chiara, Biggiogero, Maira, Calvaruso, Veronica, Svoboda, Pavel, Rincón, Tomás Cervantes, Fava, Tommaso, Podešvová, Lucie, Shanbhag, Akanksha A., Celoria, Andrea, Sgrignani, Jacopo, Stefanik, Michal, Hönig, Vaclav, Pranclova, Veronika, Michalcikova, Tereza, Prochazka, Jan, Guerrini, Giuditta, Mehn, Dora, Ciabattini, Annalisa, Abolhassani, Hassan, Jarrossay, David, Uguccioni, Mariagrazia, Medaglini, Donata, Pan-Hammarström, Qiang, Calzolai, Luigi, Fernandez, Daniel, Baldanti, Fausto, Franzetti-Pellanda, Alessandra, Garzoni, Christian, Sedlacek, Radislav, Ruzek, Daniel, Varani, Luca, Cavalli, Andrea, Barnes, Christopher O., Robbiani, Davide F.
Publicado 2022

Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein

por Bianchini, Filippo, Crivelli, Virginia, Abernathy, Morgan E., Guerra, Concetta, Palus, Martin, Muri, Jonathan, Marcotte, Harold, Piralla, Antonio, Pedotti, Mattia, De Gasparo, Raoul, Simonelli, Luca, Matkovic, Milos, Toscano, Chiara, Biggiogero, Maira, Calvaruso, Veronica, Svoboda, Pavel, Cervantes Rincón, Tomás, Fava, Tommaso, Podešvová, Lucie, Shanbhag, Akanksha A., Celoria, Andrea, Sgrignani, Jacopo, Stefanik, Michal, Hönig, Vaclav, Pranclova, Veronika, Michalcikova, Tereza, Prochazka, Jan, Guerrini, Giuditta, Mehn, Dora, Ciabattini, Annalisa, Abolhassani, Hassan, Jarrossay, David, Uguccioni, Mariagrazia, Medaglini, Donata, Pan-Hammarström, Qiang, Calzolai, Luigi, Fernandez, Daniel, Baldanti, Fausto, Franzetti-Pellanda, Alessandra, Garzoni, Christian, Sedlacek, Radislav, Ruzek, Daniel, Varani, Luca, Cavalli, Andrea, Barnes, Christopher O., Robbiani, Davide F.
Publicado 2023

Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice

por De Gasparo, Raoul, Pedotti, Mattia, Simonelli, Luca, Nickl, Petr, Muecksch, Frauke, Cassaniti, Irene, Percivalle, Elena, Lorenzi, Julio C. C., Mazzola, Federica, Magrì, Davide, Michalcikova, Tereza, Haviernik, Jan, Honig, Vaclav, Mrazkova, Blanka, Polakova, Natalie, Fortova, Andrea, Tureckova, Jolana, Iatsiuk, Veronika, Di Girolamo, Salvatore, Palus, Martin, Zudova, Dagmar, Bednar, Petr, Bukova, Ivana, Bianchini, Filippo, Mehn, Dora, Nencka, Radim, Strakova, Petra, Pavlis, Oto, Rozman, Jan, Gioria, Sabrina, Sammartino, Josè Camilla, Giardina, Federica, Gaiarsa, Stefano, Pan-Hammarström, Qiang, Barnes, Christopher O., Bjorkman, Pamela J., Calzolai, Luigi, Piralla, Antonio, Baldanti, Fausto, Nussenzweig, Michel C., Bieniasz, Paul D., Hatziioannou, Theodora, Prochazka, Jan, Sedlacek, Radislav, Robbiani, Davide F., Ruzek, Daniel, Varani, Luca
Publicado 2021