Differential Activation of Acid Sphingomyelinase and Ceramide Release Determines Invasiveness of Neisseria meningitidis into Brain Endothelial Cells

por Simonis, Alexander, Hebling, Sabrina, Gulbins, Erich, Schneider-Schaulies, Sibylle, Schubert-Unkmeir, Alexandra
Publicado 2014

A comparative analysis of remdesivir and other repurposed antivirals against SARS‐CoV‐2

por Simonis, Alexander, Theobald, Sebastian J, Fätkenheuer, Gerd, Rybniker, Jan, Malin, Jakob J
Publicado 2020

Comprehensive Host Cell-Based Screening Assays for Identification of Anti-Virulence Drugs Targeting Pseudomonas aeruginosa and Salmonella Typhimurium

por von Ambüren, Julia, Schreiber, Fynn, Fischer, Julia, Winter, Sandra, van Gumpel, Edeltraud, Simonis, Alexander, Rybniker, Jan
Publicado 2020

Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages

por Eisfeld, Hannah S., Simonis, Alexander, Winter, Sandra, Chhen, Jason, Ströh, Luisa J., Krey, Thomas, Koch, Manuel, Theobald, Sebastian J., Rybniker, Jan
Publicado 2021

Spleen tyrosine kinase mediates innate and adaptive immune crosstalk in SARS‐CoV‐2 mRNA vaccination

por Theobald, Sebastian J, Simonis, Alexander, Mudler, Julie M, Göbel, Ulrike, Acton, Richard, Kohlhas, Viktoria, Albert, Marie‐Christine, Hellmann, Anna‐Maria, Malin, Jakob J, Winter, Sandra, Hallek, Michael, Walczak, Henning, Nguyen, Phuong‐Hien, Koch, Manuel, Rybniker, Jan
Publicado 2022

Immunological fingerprint in coronavirus disease-19 convalescents with and without post-COVID syndrome

por Augustin, Max, Heyn, Ferdinand, Ullrich, Stella, Sandaradura de Silva, Ute, Albert, Marie-Christine, Linne, Viktoria, Schlotz, Maike, Schommers, Philipp, Pracht, Elisabeth, Horn, Carola, Suarez, Isabelle, Simonis, Alexander, Picard, Lea Katharina, Zoufaly, Alexander, Wenisch, Christoph, Fätkenheuer, Gerd, Gruell, Henning, Klein, Florian, Hallek, Michael, Walczak, Henning, Rybniker, Jan, Theobald, Sebastian J., Lehmann, Clara
Publicado 2023

Long‐lived macrophage reprogramming drives spike protein‐mediated inflammasome activation in COVID‐19

por Theobald, Sebastian J, Simonis, Alexander, Georgomanolis, Theodoros, Kreer, Christoph, Zehner, Matthias, Eisfeld, Hannah S, Albert, Marie‐Christine, Chhen, Jason, Motameny, Susanne, Erger, Florian, Fischer, Julia, Malin, Jakob J, Gräb, Jessica, Winter, Sandra, Pouikli, Andromachi, David, Friederike, Böll, Boris, Koehler, Philipp, Vanshylla, Kanika, Gruell, Henning, Suárez, Isabelle, Hallek, Michael, Fätkenheuer, Gerd, Jung, Norma, Cornely, Oliver A, Lehmann, Clara, Tessarz, Peter, Altmüller, Janine, Nürnberg, Peter, Kashkar, Hamid, Klein, Florian, Koch, Manuel, Rybniker, Jan
Publicado 2021