Gene Variants in the Novel Type 2 Diabetes Loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B Affect Different Aspects of Pancreatic β-Cell Function

por Simonis-Bik, Annemarie M., Nijpels, Giel, van Haeften, Timon W., Houwing-Duistermaat, Jeanine J., Boomsma, Dorret I., Reiling, Erwin, van Hove, Els C., Diamant, Michaela, Kramer, Mark H.H., Heine, Robert J., Maassen, J. Antonie, Slagboom, P. Eline, Willemsen, Gonneke, Dekker, Jacqueline M., Eekhoff, Elisabeth M., de Geus, Eco J., 't Hart, Leen M.
Publicado 2010

Combined Risk Allele Score of Eight Type 2 Diabetes Genes Is Associated With Reduced First-Phase Glucose-Stimulated Insulin Secretion During Hyperglycemic Clamps

por ‘t Hart, Leen M., Simonis-Bik, Annemarie M., Nijpels, Giel, van Haeften, Timon W., Schäfer, Silke A., Houwing-Duistermaat, Jeanine J., Boomsma, Dorret I., Groenewoud, Marlous J., Reiling, Erwin, van Hove, Els C., Diamant, Michaela, Kramer, Mark H.H., Heine, Robert J., Maassen, J. Antonie, Kirchhoff, Kerstin, Machicao, Fausto, Häring, Hans-Ulrich, Slagboom, P. Eline, Willemsen, Gonneke, Eekhoff, Elisabeth M., de Geus, Eco J., Dekker, Jacqueline M., Fritsche, Andreas
Publicado 2010

Integrative network analysis highlights biological processes underlying GLP-1 stimulated insulin secretion: A DIRECT study

por Gudmundsdottir, Valborg, Pedersen, Helle Krogh, Allebrandt, Karla Viviani, Brorsson, Caroline, van Leeuwen, Nienke, Banasik, Karina, Mahajan, Anubha, Groves, Christopher J., van de Bunt, Martijn, Dawed, Adem Y., Fritsche, Andreas, Staiger, Harald, Simonis-Bik, Annemarie M. C., Deelen, Joris, Kramer, Mark H. H., Dietrich, Axel, Hübschle, Thomas, Willemsen, Gonneke, Häring, Hans-Ulrich, de Geus, Eco J. C., Boomsma, Dorret I., Eekhoff, Elisabeth M. W., Ferrer, Jorge, McCarthy, Mark I., Pearson, Ewan R., Gupta, Ramneek, Brunak, Søren, ‘t Hart, Leen M.
Publicado 2018

The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway

por ‘t Hart, Leen M., Fritsche, Andreas, Nijpels, Giel, van Leeuwen, Nienke, Donnelly, Louise A., Dekker, Jacqueline M., Alssema, Marjan, Fadista, Joao, Carlotti, Françoise, Gjesing, Anette P., Palmer, Colin N.A., van Haeften, Timon W., Herzberg-Schäfer, Silke A., Simonis-Bik, Annemarie M.C., Houwing-Duistermaat, Jeanine J., Helmer, Quinta, Deelen, Joris, Guigas, Bruno, Hansen, Torben, Machicao, Fausto, Willemsen, Gonneke, Heine, Robert J., Kramer, Mark H.H., Holst, Jens J., de Koning, Eelco J.P., Häring, Hans-Ulrich, Pedersen, Oluf, Groop, Leif, de Geus, Eco J.C., Slagboom, P. Eline, Boomsma, Dorret I., Eekhoff, Elisabeth M.W., Pearson, Ewan R., Diamant, Michaela
Publicado 2013

Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp

por van Vliet-Ostaptchouk, Jana V., van Haeften, Timon W., Landman, Gijs W. D., Reiling, Erwin, Kleefstra, Nanne, Bilo, Henk J. G., Klungel, Olaf H., de Boer, Anthonius, van Diemen, Cleo C., Wijmenga, Cisca, Boezen, H. Marike, Dekker, Jacqueline M., van 't Riet, Esther, Nijpels, Giel, Welschen, Laura M. C., Zavrelova, Hata, Bruin, Elinda J., Elbers, Clara C., Bauer, Florianne, Onland-Moret, N. Charlotte, van der Schouw, Yvonne T., Grobbee, Diederick E., Spijkerman, Annemieke M. W., van der A, Daphne L., Simonis-Bik, Annemarie M., Eekhoff, Elisabeth M. W., Diamant, Michaela, Kramer, Mark H. H., Boomsma, Dorret I., de Geus, Eco J., Willemsen, Gonneke, Slagboom, P. Eline, Hofker, Marten H., 't Hart, Leen M.
Publicado 2012

Correction: Common Variants in the Type 2 Diabetes KCNQ1 Gene Are Associated with Impairments in Insulin Secretion During Hyperglycaemic Glucose Clamp

por van Vliet-Ostaptchouk, Jana V., van Haeften, Timon W., Landman, Gijs W. D., Reiling, Erwin, Kleefstra, Nanne, Bilo, Henk J. G., Klungel, Olaf H., de Boer, Anthonius, van Diemen, Cleo C., Wijmenga, Cisca, Boezen, H. Marike, Dekker, Jacqueline M., van 't Riet, Esther, Nijpels, Giel, Welschen, Laura M. C., Zavrelova, Hata, Bruin, Elinda J., Elbers, Clara C., Bauer, Florianne, Onland-Moret, N. Charlotte, van der Schouw, Yvonne T., Grobbee, Diederick E., Spijkerman, Annemieke M. W., van der A, Daphne L., Simonis-Bik, Annemarie M., Eekhoff, Elisabeth M. W., Diamant, Michaela, Kramer, Mark H. H., Boomsma, Dorret I., de Geus, Eco J., Willemsen, Gonneke, Slagboom, P. Eline, Hofker, Marten H., 't Hart, Leen M.
Publicado 2012

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study

por Molnos, Sophie, Wahl, Simone, Haid, Mark, Eekhoff, E. Marelise W., Pool, René, Floegel, Anna, Deelen, Joris, Much, Daniela, Prehn, Cornelia, Breier, Michaela, Draisma, Harmen H., van Leeuwen, Nienke, Simonis-Bik, Annemarie M. C., Jonsson, Anna, Willemsen, Gonneke, Bernigau, Wolfgang, Wang-Sattler, Rui, Suhre, Karsten, Peters, Annette, Thorand, Barbara, Herder, Christian, Rathmann, Wolfgang, Roden, Michael, Gieger, Christian, Kramer, Mark H. H., van Heemst, Diana, Pedersen, Helle K., Gudmundsdottir, Valborg, Schulze, Matthias B., Pischon, Tobias, de Geus, Eco J. C., Boeing, Heiner, Boomsma, Dorret I., Ziegler, Anette G., Slagboom, P. Eline, Hummel, Sandra, Beekman, Marian, Grallert, Harald, Brunak, Søren, McCarthy, Mark I., Gupta, Ramneek, Pearson, Ewan R., Adamski, Jerzy, ’t Hart, Leen M.
Publicado 2017

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

por Wood, Andrew R., Jonsson, Anna, Jackson, Anne U., Wang, Nan, van Leewen, Nienke, Palmer, Nicholette D., Kobes, Sayuko, Deelen, Joris, Boquete-Vilarino, Lorena, Paananen, Jussi, Stančáková, Alena, Boomsma, Dorret I., de Geus, Eco J.C., Eekhoff, Elisabeth M.W., Fritsche, Andreas, Kramer, Mark, Nijpels, Giel, Simonis-Bik, Annemarie, van Haeften, Timon W., Mahajan, Anubha, Boehnke, Michael, Bergman, Richard N., Tuomilehto, Jaakko, Collins, Francis S., Mohlke, Karen L., Banasik, Karina, Groves, Christopher J., McCarthy, Mark I., Pearson, Ewan R., Natali, Andrea, Mari, Andrea, Buchanan, Thomas A., Taylor, Kent D., Xiang, Anny H., Gjesing, Anette P., Grarup, Niels, Eiberg, Hans, Pedersen, Oluf, Chen, Yii-Derr, Laakso, Markku, Norris, Jill M., Smith, Ulf, Wagenknecht, Lynne E., Baier, Leslie, Bowden, Donald W., Hansen, Torben, Walker, Mark, Watanabe, Richard M., ‘t Hart, Leen M., Hanson, Robert L., Frayling, Timothy M.
Publicado 2017