PSMA expression in the Hi‐Myc model; extended utility of a representative model of prostate adenocarcinoma for biological insight and as a drug discovery tool

por Simons, Brian W., Turtle, Norman F., Ulmert, David H., Abou, Diane S., Thorek, Daniel L. J.
Publicado 2019

Absence of myeloid Klf4 reduces prostate cancer growth with pro-atherosclerotic activation of tumor myeloid cells and infiltration of CD8 T cells

por Barakat, David J., Suresh, Rahul, Barberi, Theresa, Pienta, Kenneth J., Simons, Brian W., Friedman, Alan D.
Publicado 2018

Spatial analysis of nanoparticle distribution in human breast xenografts reveals nanoparticles targeted to cancer cells localized with tumor-associated stromal cells

por Healy, Sean, Henderson, Elizabeth T, Ke, Suqi, Kelly, Jacqueline, Simons, Brian W, Hu, Chen, Ivkov, Robert, Korangath, Preethi
Publicado 2023

Sox9 is required for prostate development and prostate cancer initiation

por Huang, Zhenhua, Hurley, Paula J, Simons, Brian W, Marchionni, Luigi, Berman, David M, Ross, Ashley E, Schaeffer, Edward M
Publicado 2012

Tumorigenic potential of circulating prostate tumor cells

por Carvalho, Filipe LF., Simons, Brian W., Antonarakis, Emmanuel S., Rasheed, Zeshaan, Douglas, Nora, Villegas, Daniela, Matsui, William, Berman, David M.
Publicado 2013

Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma

por Barbhuiya, Mustafa A., Mirando, Adam C., Simons, Brian W., Lemtiri-Chlieh, Ghali, Green, Jordan J., Popel, Aleksander S., Pandey, Niranjan B., Tran, Phuoc T.
Publicado 2017

A mouse model of prostate cancer bone metastasis in a syngeneic immunocompetent host

por Simons, Brian W., Kothari, Vishal, Benzon, Benjamin, Ghabili, Kamyar, Hughes, Robert, Zarif, Jelani C., Ross, Ashley E., Hurley, Paula J., Schaeffer, Edward M.
Publicado 2019

The ChorioAnchor: Design and Testing of a Novel Chorioamniotic Anchoring Device to Enable Percutaneous Fetoscopic Surgery

por Byju, Achu G., Diemer, Ashley, Luk, Christine, Heffernan, Michael J., Belfort, Michael A., Simons, Brian W., Koh, Chester J., Haridas, Balakrishna, Espinoza, Jimmy
Publicado 2022

K-Ras and p53 mouse model with molecular characteristics of human rhabdomyosarcoma and translational applications

por Nakahata, Kengo, Simons, Brian W., Pozzo, Enrico, Shuck, Ryan, Kurenbekova, Lyazat, Prudowsky, Zachary, Dholakia, Kshiti, Coarfa, Cristian, Patel, Tajhal D., Donehower, Lawrence A., Yustein, Jason T.
Publicado 2022

Blind Image Restoration Enhances Digital Autoradiographic Imaging of Radiopharmaceutical Tissue Distribution

por Peng, Lu, Nadia, Benabdallah, Wen, Jiang, Simons, Brian W., Hanwen, Zhang, Hobbs, Robert F., David, Ulmert, Baumann, Brian C., Pachynski, Russell K., Jha, Abhinav K., Thorek, Daniel L.J.
Publicado 2022

Improved (223)Ra Therapy with Combination Epithelial Sodium Channel Blockade

por Abou, Diane S., Fears, Amanda, Summer, Lucy, Longtine, Mark, Benabdallah, Nadia, Riddle, Ryan C., Ulmert, David, Michalski, Jeff M., Wahl, Richard L., Chesner, Denise, Doucet, Michele, Zachos, Nicholas C., Simons, Brian W., Thorek, Daniel L.J.
Publicado 2021

Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small cell lung cancer

por Yochum, Zachary A., Cades, Jessica, Wang, Hailun, Chatterjee, Suman, Simons, Brian W., O’Brien, James P., Khetarpal, Susheel K., Lemtiri-Chlieh, Ghali, Myers, Kayla V., Huang, Eric H.-B., Rudin, Charles M., Tran, Phuoc T., Burns, Timothy F.
Publicado 2018

Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation

por Schneider, Craig S., Xu, Qingguo, Boylan, Nicholas J., Chisholm, Jane, Tang, Benjamin C., Schuster, Benjamin S., Henning, Andreas, Ensign, Laura M., Lee, Ethan, Adstamongkonkul, Pichet, Simons, Brian W., Wang, Sho-Yu S., Gong, Xiaoqun, Yu, Tao, Boyle, Michael P., Suk, Jung Soo, Hanes, Justin
Publicado 2017

[(18)F]-Labeled PARP-1 PET imaging of PSMA targeted alpha particle radiotherapy response

por Zhang, Hanwen, Abou, Diane, Lu, Peng, Hasson, Abbie Meghan, Villmer, Alexandria, Benabdallah, Nadia, Jiang, Wen, Ulmert, David, Carlin, Sean, Rogers, Buck E., Turtle, Norman F., McDevitt, Michael R., Baumann, Brian, Simons, Brian W., Dehdashti, Farrokh, Zhou, Dong, Thorek, Daniel L. J.
Publicado 2022

Development of a Reactive Stroma Associated with Prostatic Intraepithelial Neoplasia in EAF2 Deficient Mice

por Pascal, Laura E., Ai, Junkui, Masoodi, Khalid Z., Wang, Yujuan, Wang, Dan, Eisermann, Kurtis, Rigatti, Lora H., O’Malley, Katherine J., Ma, Hei M., Wang, Xinhui, Dar, Javid A., Parwani, Anil V., Simons, Brian W., Ittman, Michael M., Li, Luyuan, Davies, Benjamin J., Wang, Zhou
Publicado 2013

Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer

por Korangath, Preethi, Barnett, James D., Sharma, Anirudh, Henderson, Elizabeth T., Stewart, Jacqueline, Yu, Shu-Han, Kandala, Sri Kamal, Yang, Chun-Ting, Caserto, Julia S., Hedayati, Mohammad, Armstrong, Todd D., Jaffee, Elizabeth, Gruettner, Cordula, Zhou, Xian C., Fu, Wei, Hu, Chen, Sukumar, Saraswati, Simons, Brian W., Ivkov, Robert
Publicado 2020

AIM1 is an actin-binding protein that suppresses cell migration and micrometastatic dissemination

por Haffner, Michael C., Esopi, David M., Chaux, Alcides, Gürel, Meltem, Ghosh, Susmita, Vaghasia, Ajay M., Tsai, Harrison, Kim, Kunhwa, Castagna, Nicole, Lam, Hong, Hicks, Jessica, Wyhs, Nicolas, Biswal Shinohara, Debika, Hurley, Paula J., Simons, Brian W., Schaeffer, Edward M., Lotan, Tamara L., Isaacs, William B., Netto, George J., De Marzo, Angelo M., Nelson, William G., An, Steven S., Yegnasubramanian, Srinivasan
Publicado 2017

Genetic Alterations Detected in Cell-Free DNA Are Associated With Enzalutamide and Abiraterone Resistance in Castration-Resistant Prostate Cancer

por Torquato, Samantha, Pallavajjala, Aparna, Goldstein, Alexa, Valda Toro, Patricia, Silberstein, John L., Lee, Justin, Nakazawa, Mary, Waters, Ian, Chu, David, Shinn, Daniel, Groginski, Taylor, Hughes, Robert M., Simons, Brian W., Khan, Hamda, Feng, Zhaoyong, Carducci, Michael A., Paller, Channing J., Denmeade, Samuel R., Kressel, Bruce, Eisenberger, Mario A., Antonarakis, Emmanuel S., Trock, Bruce J., Park, Ben H., Hurley, Paula J.
Publicado 2019