Telomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G(1 )checkpoint function

por Simpson, Dennis A, Livanos, Elizabeth, Heffernan, Timothy P, Kaufmann, William K
Publicado 2005

Oncogenic BRAF(V600E) Induces Clastogenesis and UVB Hypersensitivity

por Simpson, Dennis A., Lemonie, Nathalay, Morgan, David S., Gaddameedhi, Shobhan, Kaufmann, William K.
Publicado 2015

A Flexible and Qualitatively Stable Model for Cell Cycle Dynamics Including DNA Damage Effects

por Jeffries, Clark D., Johnson, Charles R., Zhou, Tong, Simpson, Dennis A., Kaufmann, William K.
Publicado 2012

Topoisomerase IIα maintains genomic stability through decatenation G(2) checkpoint signaling

por Bower, Jacquelyn J., Karaca, Gamze F., Zhou, Yingchun, Simpson, Dennis A., Cordeiro-Stone, Marila, Kaufmann, William K.
Publicado 2010

Estimating relative CWD susceptibility and disease progression in farmed white-tailed deer with rare PRNP alleles

por Haley, Nicholas J., Merrett, Kahla, Buros Stein, Amy, Simpson, Dennis, Carlson, Andrew, Mitchell, Gordon, Staskevicius, Antanas, Nichols, Tracy, Lehmkuhl, Aaron D., Thomsen, Bruce V.
Publicado 2019

Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks

por Feng, Wanjuan, Simpson, Dennis A, Cho, Jang-Eun, Carvajal-Garcia, Juan, Smith, Chelsea M, Headley, Kathryn M, Hathaway, Nate, Ramsden, Dale A, Gupta, Gaorav P
Publicado 2021

Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells

por Bower, Jacquelyn J., Vance, Leah D., Psioda, Matthew, Smith-Roe, Stephanie L., Simpson, Dennis A., Ibrahim, Joseph G., Hoadley, Katherine A., Perou, Charles M., Kaufmann, William K.
Publicado 2017

SWI/SNF complexes are required for full activation of the DNA-damage response

por Smith-Roe, Stephanie L., Nakamura, Jun, Holley, Darcy, Chastain, Paul D., Rosson, Gary B., Simpson, Dennis A., Ridpath, John R., Kaufman, David G., Kaufmann, William K., Bultman, Scott J.
Publicado 2015

Profiles of Global Gene Expression in Ionizing-Radiation–Damaged Human Diploid Fibroblasts Reveal Synchronization behind the G(1) Checkpoint in a G(0)-like State of Quiescence

por Zhou, Tong, Chou, Jeff W., Simpson, Dennis A., Zhou, Yingchun, Mullen, Thomas E., Medeiros, Margarida, Bushel, Pierre R., Paules, Richard S., Yang, Xuebin, Hurban, Patrick, Lobenhofer, Edward K., Kaufmann, William K.
Publicado 2006

Genetic determinants of cellular addiction to DNA polymerase theta

por Feng, Wanjuan, Simpson, Dennis A., Carvajal-Garcia, Juan, Price, Brandon A., Kumar, Rashmi J., Mose, Lisle E., Wood, Richard D., Rashid, Naim, Purvis, Jeremy E., Parker, Joel S., Ramsden, Dale A., Gupta, Gaorav P.
Publicado 2019

Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency

por Kumar, Rashmi J, Chao, Hui Xiao, Simpson, Dennis A, Feng, Wanjuan, Cho, Min-Guk, Roberts, Victoria R, Sullivan, Aurora R, Shah, Sonam J, Wozny, Anne-Sophie, Fagan-Solis, Katerina, Kumar, Sunil, Luthman, Adam, Ramsden, Dale A, Purvis, Jeremy E, Gupta, Gaorav P
Publicado 2020

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

por Krais, John J., Glass, David J., Chudoba, Ilse, Wang, Yifan, Feng, Wanjuan, Simpson, Dennis, Patel, Pooja, Liu, Zemin, Neumann-Domer, Ryan, Betsch, Robert G., Bernhardy, Andrea J., Bradbury, Alice M., Conger, Jason, Yueh, Wei-Ting, Nacson, Joseph, Pomerantz, Richard T., Gupta, Gaorav P., Testa, Joseph R., Johnson, Neil
Publicado 2023