Sirtuin Evolution at the Dawn of Animal Life

por Gold, David A, Sinclair, David A
Publicado 2022

The economic value of targeting aging

por Scott, Andrew J., Ellison, Martin, Sinclair, David A.
Publicado 2021

Aging: past, present and future

por Blagosklonny, Mikhail V., Campisi, Judith, Sinclair, David A.
Publicado 2009

Can artificial intelligence identify effective COVID‐19 therapies?

por Schultz, Michael B, Vera, Daniel, Sinclair, David A
Publicado 2020

NAD(+) in COVID-19 and viral infections

por Zheng, Minyan, Schultz, Michael B., Sinclair, David A.
Publicado 2022

Oxidative Priority, Meal Frequency, and the Energy Economy of Food and Activity: Implications for Longevity, Obesity, and Cardiometabolic Disease

por Cronise, Raymond J., Sinclair, David A., Bremer, Andrew A.
Publicado 2017

Why does COVID-19 disproportionately affect older people?

por Mueller, Amber L., McNamara, Maeve S., Sinclair, David A.
Publicado 2020

Protective effects of sirtuins in cardiovascular diseases: from bench to bedside

por Winnik, Stephan, Auwerx, Johan, Sinclair, David A., Matter, Christian M.
Publicado 2015

MSN2 and MSN4 Link Calorie Restriction and TOR to Sirtuin-Mediated Lifespan Extension in Saccharomyces cerevisiae

por Medvedik, Oliver, Lamming, Dudley W, Kim, Keyman D, Sinclair, David A
Publicado 2007

The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction

por Rascón, Brenda, Hubbard, Basil P., Sinclair, David A., Amdam, Gro V.
Publicado 2012

Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stability

por Kim, Jeongkyu, Sturgill, David, Tran, Andy D., Sinclair, David A., Oberdoerffer, Philipp
Publicado 2016

Head to Head Comparison of Short-Term Treatment with the NAD(+) Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice

por Uddin, Golam M., Youngson, Neil A., Sinclair, David A., Morris, Margaret J.
Publicado 2016

Applying the AFRAID and FRIGHT Clocks to Novel Preclinical Mouse Models of Polypharmacy

por Mach, John, Kane, Alice E, Howlett, Susan E, Sinclair, David A, Hilmer, Sarah N
Publicado 2022

Dietary restriction involves NAD(+)-dependent mechanisms and a shift toward oxidative metabolism

por Moroz, Natalie, Carmona, Juan J, Anderson, Edward, Hart, Anne C, Sinclair, David A, Blackwell, T Keith
Publicado 2014

Correction: Nicotinamide Impairs Entry into and Exit from Meiosis I in Mouse Oocytes

por Riepsamen, Angelique, Wu, Lindsay, Lau, Laurin, Listijono, Dave, Ledger, William, Sinclair, David A, Homer, Hayden
Publicado 2015

Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: comparison with exercise

por Uddin, Golam Mezbah, Youngson, Neil A., Doyle, Bronte M., Sinclair, David A., Morris, Margaret J.
Publicado 2017

Human age reversal: Fact or fiction?

por Johnson, Adiv A., English, Bradley W., Shokhirev, Maxim N., Sinclair, David A., Cuellar, Trinna L.
Publicado 2022

Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers

por Uddin, Golam M., Youngson, Neil A., Chowdhury, Sabiha S., Hagan, Christopher, Sinclair, David A., Morris, Margaret J.
Publicado 2020

Novel feature selection methods for construction of accurate epigenetic clocks

por Li, Adam, Mueller, Amber, English, Brad, Arena, Anthony, Vera, Daniel, Kane, Alice E., Sinclair, David A.
Publicado 2022

Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy

por Armour, Sean M., Baur, Joseph A., Hsieh, Sherry N., Land-Bracha, Abigail, Thomas, Sheila M., Sinclair, David A.
Publicado 2009