Full and partial agonists evoke distinct structural changes in opening the muscle acetylcholine receptor channel

por Mukhtasimova, Nuriya, Sine, Steven M.
Publicado 2018

Nicotinic Receptor Fourth Transmembrane Domain: Hydrogen Bonding by Conserved Threonine Contributes to Channel Gating Kinetics

por Bouzat, Cecilia, Barrantes, Francisco, Sine, Steven
Publicado 2000

Invariant Aspartic Acid in Muscle Nicotinic Receptor Contributes Selectively to the Kinetics of Agonist Binding

por Lee, Won Yong, Sine, Steven M.
Publicado 2004

Unmasking coupling between channel gating and ion permeation in the muscle nicotinic receptor

por Strikwerda, John R, Sine, Steven M
Publicado 2021

Initial Coupling of Binding to Gating Mediated by Conserved Residues in the Muscle Nicotinic Receptor

por Mukhtasimova, Nuriya, Free, Chris, Sine, Steven M.
Publicado 2005

Mechanism of Tacrine Block at Adult Human Muscle Nicotinic Acetylcholine Receptors

por Prince, Richard J., Pennington, Richard A., Sine, Steven M.
Publicado 2002

Nicotinic Receptor Interloop Proline Anchors β1-β2 and Cys loops in Coupling Agonist Binding to Channel Gating

por Lee, Won Yong, Free, Chris R., Sine, Steven M.
Publicado 2008

The Extracellular Linker of Muscle Acetylcholine Receptor Channels Is a Gating Control Element

por Grosman, Claudio, Salamone, Frank N., Sine, Steven M., Auerbach, Anthony
Publicado 2000

Improved resolution of single channel dwell times reveals mechanisms of binding, priming, and gating in muscle AChR

por Mukhtasimova, Nuriya, daCosta, Corrie J.B., Sine, Steven M.
Publicado 2016

Detection and Trapping of Intermediate States Priming Nicotinic Receptor Channel Opening

por Mukhtasimova, Nuriya, Lee, Won Yong, Wang, Hai-Long, Sine, Steven M.
Publicado 2009

Stoichiometry for α-bungarotoxin block of α7 acetylcholine receptors

por daCosta, Corrie J. B., Free, Chris R., Sine, Steven M.
Publicado 2015

Targeted Molecular Dynamics Study of C-Loop Closure and Channel Gating in Nicotinic Receptors

por Cheng, Xiaolin, Wang, Hailong, Grant, Barry, Sine, Steven M, McCammon, J. Andrew
Publicado 2006

Mechanism of calcium potentiation of the α7 nicotinic acetylcholine receptor

por Natarajan, Kathiresan, Mukhtasimova, Nuriya, Corradi, Jeremías, Lasala, Matías, Bouzat, Cecilia, Sine, Steven M.
Publicado 2020

Genetic Variant in Nicotinic Receptor α4-Subunit Causes Sleep-Related Hyperkinetic Epilepsy via Increased Channel Opening

por Mazzaferro, Simone, Msekela, Deborah J., Cooper, Edward C., Maheshwari, Atul, Sine, Steven M.
Publicado 2022

Control of Cation Permeation through the Nicotinic Receptor Channel

por Wang, Hai-Long, Cheng, Xiaolin, Taylor, Palmer, McCammon, J. Andrew, Sine, Steven M
Publicado 2008

Mutation in the M1 Domain of the Acetylcholine Receptor α Subunit Decreases the Rate of Agonist Dissociation

por Wang, Hai-Long, Auerbach, Anthony, Bren, Nina, Ohno, Kinji, Engel, Andrew G., Sine, Steven M.
Publicado 1997

Slow‐channel myasthenia due to novel mutation in M2 domain of AChR delta subunit

por Shen, Xin‐Ming, Milone, Margherita, Wang, Hang‐Long, Banwell, Brenda, Selcen, Duygu, Sine, Steven M., Engel, Andrew G.
Publicado 2019

Naturally Occurring Mutations at the Acetylcholine Receptor Binding Site Independently Alter ACh Binding and Channel Gating

por Sine, Steven M., Shen, Xing-Ming, Wang, Hai-Long, Ohno, Kinji, Lee, Won-Yong, Tsujino, Akira, Brengmann, Joan, Bren, Nina, Vajsar, Jiri, Engel, Andrew G.
Publicado 2002

Fundamental Gating Mechanism of Nicotinic Receptor Channel Revealed by Mutation Causing a Congenital Myasthenic Syndrome

por Wang, Hai-Long, Ohno, Kinji, Milone, Margherita, Brengman, Joan M., Evoli, Amelia, Batocchi, Anna-Paola, Middleton, Lefkos T., Christodoulou, Kyproula, Engel, Andrew G., Sine, Steven M.
Publicado 2000

Alcohol reduces muscle fatigue through atomistic interactions with nicotinic receptors

por Noori, Hamid R., Mücksch, Christian, Vengeliene, Valentina, Schönig, Kai, Takahashi, Tatiane T., Mukhtasimova, Nuriya, Bagher Oskouei, Maryam, Mosqueira, Matias, Bartsch, Dusan, Fink, Rainer, Urbassek, Herbert M., Spanagel, Rainer, Sine, Steven M.
Publicado 2018