Sulforaphane-Induced Klf9/Prdx6 Axis Acts as a Molecular Switch to Control Redox Signaling and Determines Fate of Cells

por Chhunchha, Bhavana, Kubo, Eri, Singh, Dhirendra P.
Publicado 2019

Clock Protein Bmal1 and Nrf2 Cooperatively Control Aging or Oxidative Response and Redox Homeostasis by Regulating Rhythmic Expression of Prdx6

por Chhunchha, Bhavana, Kubo, Eri, Singh, Dhirendra P.
Publicado 2020

Switching of Redox Signaling by Prdx6 Expression Decides Cellular Fate by Hormetic Phenomena Involving Nrf2 and Reactive Oxygen Species

por Chhunchha, Bhavana, Kubo, Eri, Singh, Dhirendra P.
Publicado 2022

Obligatory Role of AMPK Activation and Antioxidant Defense Pathway in the Regulatory Effects of Metformin on Cellular Protection and Prevention of Lens Opacity

por Chhunchha, Bhavana, Kubo, Eri, Singh, Dhirendra P.
Publicado 2022

Involvement of metabotropic glutamate receptor 5, AKT/PI3K Signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes

por Shah, Ankit, Silverstein, Peter S, Singh, Dhirendra P, Kumar, Anil
Publicado 2012

Dynamic and differential regulation in the microRNA expression in the developing and mature cataractous rat lens

por Kubo, Eri, Hasanova, Nailia, Sasaki, Hiroshi, Singh, Dhirendra P
Publicado 2013

Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation

por Chhunchha, Bhavana, Kubo, Eri, Fatma, Nigar, Singh, Dhirendra P
Publicado 2017

Sumoylation-deficient Prdx6 repairs aberrant Sumoylation-mediated Sp1 dysregulation-dependent Prdx6 repression and cell injury in aging and oxidative stress

por Chhunchha, Bhavana, Kubo, Eri, Singh, Prerna, Singh, Dhirendra P.
Publicado 2018

Roles of TGF β and FGF Signals in the Lens: Tropomyosin Regulation for Posterior Capsule Opacity

por Kubo, Eri, Shibata, Teppei, Singh, Dhirendra P., Sasaki, Hiroshi
Publicado 2018

Ginkgolic Acid Rescues Lens Epithelial Cells from Injury Caused by Redox Regulated-Aberrant Sumoylation Signaling by Reviving Prdx6 and Sp1 Expression and Activities

por Chhunchha, Bhavana, Singh, Prerna, Singh, Dhirendra P., Kubo, Eri
Publicado 2018

Prdx6 retards senescence and restores trabecular meshwork cell health by regulating reactive oxygen species

por Chhunchha, Bhavana, Singh, Prerna, Stamer, W Daniel, Singh, Dhirendra P
Publicado 2017

Unraveling the role of membrane microdomains during microbial infections

por Bagam, Prathyusha, Singh, Dhirendra P., Inda, Maria Eugenia, Batra, Sanjay
Publicado 2017

Engineered Sumoylation-Deficient Prdx6 Mutant Protein-Loaded Nanoparticles Provide Increased Cellular Defense and Prevent Lens Opacity

por Chhunchha, Bhavana, Kubo, Eri, Kompella, Uday B., Singh, Dhirendra P.
Publicado 2021

A clinical study of fetal outcome following early and delayed cord clamping in births associated with anemia in pregnancy

por Singh, Lata, Singh, Dhirendra P., Deepika, Raghunandan, Chitra, Dhoat, Navdeep
Publicado 2022

Hydralazine Revives Cellular and Ocular Lens Health-Span by Ameliorating the Aging and Oxidative-Dependent Loss of the Nrf2-Activated Cellular Stress Response

por Chhunchha, Bhavana, Kubo, Eri, Krueger, Ronald R., Singh, Dhirendra P.
Publicado 2023

Prdx6 Regulates Nlrp3 Inflammasome Activation-Driven Inflammatory Response in Lens Epithelial Cells

por Chhunchha, Bhavana, Kumar, Rakesh, Kubo, Eri, Thakur, Priyanka, Singh, Dhirendra P.
Publicado 2023

Synergistic Cooperation between Methamphetamine and HIV-1 gsp120 through the P13K/Akt Pathway Induces IL-6 but not IL-8 Expression in Astrocytes

por Shah, Ankit, Silverstein, Peter S., Kumar, Santosh, Singh, Dhirendra P., Kumar, Anil
Publicado 2012

Elevated tropomyosin expression is associated with epithelial–mesenchymal transition of lens epithelial cells

por Kubo, Eri, Hasanova, Nailia, Fatma, Nigar, Sasaki, Hiroshi, Singh, Dhirendra P
Publicado 2013

Correction: Synergistic Cooperation between Methamphetamine and HIV-1 gsp120 through the P13K/Akt Pathway Induces IL-6 but not IL-8 Expression in Astrocytes

por Shah, Ankit, Silverstein, Peter S., Kumar, Santosh, Singh, Dhirendra P., Kumar, Anil
Publicado 2013

Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress

por Kubo, Eri, Chhunchha, Bhavana, Singh, Prerna, Sasaki, Hiroshi, Singh, Dhirendra P.
Publicado 2017