Impact and Intricacies of Bone Marrow Microenvironment in B-cell Lymphomas: From Biology to Therapy

por Sircar, Anuvrat, Chowdhury, Sayan Mullick, Hart, Amber, Bell, William Connor, Singh, Satishkumar, Sehgal, Lalit, Epperla, Narendranath
Publicado 2020

Integration of Metabolomics and Gene Expression Profiling Elucidates IL4I1 as Modulator of Ibrutinib Resistance in ABC-Diffuse Large B Cell Lymphoma

por Choueiry, Fouad, Singh, Satishkumar, Sircar, Anuvrat, Laliotis, Georgios, Sun, Xiaowei, Chavdoula, Evangelia, Zhang, Shiqi, Helmig-Mason, JoBeth, Hart, Amber, Epperla, Narendranath, Tsichlis, Philip, Baiocchi, Robert, Alinari, Lapo, Zhu, Jiangjiang, Sehgal, Lalit
Publicado 2021

Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma

por Sircar, Anuvrat, Singh, Satishkumar, Xu-Monette, Zijun Y., Coyle, Krysta Mila, Hilton, Laura K., Chavdoula, Evangelia, Ranganathan, Parvathi, Jain, Neeraj, Hanel, Walter, Tsichlis, Philip, Alinari, Lapo, Peterson, Blake R., Tao, Jianguo, Muthusamy, Natarajan, Baiocchi, Robert, Epperla, Narendranath, Young, Ken H., Morin, Ryan, Sehgal, Lalit
Publicado 2023

Inhibition of Bromodomain and Extra Terminal (BET) Domain Activity Modulates the IL-23R/IL-17 Axis and Suppresses Acute Graft-Versus-Host Disease

por Snyder, Katiri J., Choe, Hannah K., Gao, Yandi, Sell, Natalie E., Braunreiter, Kara M., Zitzer, Nina C., Neidemire-Colley, Lotus, Kalyan, Sonu, Dorrance, Adrienne M., Keller, Andrea, Mihaylova, Maria M., Singh, Satishkumar, Sehgal, Lalit, Bollag, Gideon, Ma, Yan, Powell, Ben, Devine, Steven M., Ranganathan, Parvathi
Publicado 2021

RETRACTED ARTICLE: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing

por Laliotis, Georgios I., Chavdoula, Evangelia, Paraskevopoulou, Maria D., Kaba, Abdul, La Ferlita, Alessandro, Singh, Satishkumar, Anastas, Vollter, Nair, Keith A., Orlacchio, Arturo, Taraslia, Vasiliki, Vlachos, Ioannis, Capece, Marina, Hatzigeorgiou, Artemis, Palmieri, Dario, Tsatsanis, Christos, Alaimo, Salvatore, Sehgal, Lalit, Carbone, David P., Coppola, Vincenzo, Tsichlis, Philip N.
Publicado 2021

Retraction Note: AKT3-mediated IWS1 phosphorylation promotes the proliferation of EGFR-mutant lung adenocarcinomas through cell cycle-regulated U2AF2 RNA splicing

por Laliotis, Georgios I., Chavdoula, Evangelia, Paraskevopoulou, Maria D., Kaba, Abdul, La Ferlita, Alessandro, Singh, Satishkumar, Anastas, Vollter, Nair, Keith A., Orlacchio, Arturo, Taraslia, Vasiliki, Vlachos, Ioannis, Capece, Marina, Hatzigeorgiou, Artemis, Palmieri, Dario, Tsatsanis, Christos, Alaimo, Salvatore, Sehgal, Lalit, Carbone, David P., Coppola, Vincenzo, Tsichlis, Philip N.
Publicado 2022

Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma

por Zhao, Xiaohong, Wang, Michelle Y., Jiang, Huijuan, Lwin, Tint, Park, Paul M., Gao, Jing, Meads, Mark B., Ren, Yuan, Li, Tao, Sun, Jiao, Fahmi, Naima Ahmed, Singh, Satishkumar, Sehgal, Lalit, Wang, Xuefeng, Silva, Ariosto S., Sotomayor, Eduardo M., Shain, Kenneth H., Cleveland, John L., Wang, Michael, Zhang, Wei, Qi, Jun, Shah, Bijal D., Tao, Jianguo
Publicado 2021

PRMT5 inhibition drives therapeutic vulnerability to combination treatment with BCL-2 inhibition in mantle cell lymphoma

por Brown-Burke, Fiona, Hwang, Inah, Sloan, Shelby, Hinterschied, Claire, Helmig-Mason, JoBeth, Long, Mackenzie, Chan, Wing Keung, Prouty, Alexander, Chung, Ji-Hyun, Zhang, Yang, Singh, Satishkumar, Youssef, Youssef, Bhagwat, Neha, Chen, Zhengming, Chen-Kiang, Selina, Di Liberto, Maurizio, Elemento, Olivier, Sehgal, Lalit, Alinari, Lapo, Vaddi, Kris, Scherle, Peggy, Lapalombella, Rosa, Paik, Jihye, Baiocchi, Robert A.
Publicado 2023