A metric for evaluating biological information in gene sets and its application to identify co-expressed gene clusters in PBMC

por Bennett, Jason, Pomaznoy, Mikhail, Singhania, Akul, Peters, Bjoern
Publicado 2021

Effective Delivery of PEGylated siRNA-Containing Lipoplexes to Extraperitoneal Tumours following Intraperitoneal Administration

por Singhania, Akul, Wu, Sherry Y., McMillan, Nigel A. J.
Publicado 2011

Gene expression in human fungal pathogen Coccidioides immitis changes as arthroconidia differentiate into spherules and mature

por Viriyakosol, Suganya, Singhania, Akul, Fierer, Joshua, Goldberg, Jonathan, Kirkland, Theo N, Woelk, Christopher H
Publicado 2013

Factors regulated by interferon gamma and hypoxia-inducible factor 1A contribute to responses that protect mice from Coccidioides immitis infection

por Woelk, Christopher H, Zhang, Jin X, Walls, Lorraine, Viriyakosol, Suganya, Singhania, Akul, Kirkland, Theo N, Fierer, Joshua
Publicado 2012

Altered Epithelial Gene Expression in Peripheral Airways of Severe Asthma

por Singhania, Akul, Rupani, Hitasha, Jayasekera, Nivenka, Lumb, Simon, Hales, Paul, Gozzard, Neil, Davies, Donna E., Woelk, Christopher H., Howarth, Peter H.
Publicado 2017

Gender-Dependent Differences in Plasma Matrix Metalloproteinase-8 Elevated in Pulmonary Tuberculosis

por Sathyamoorthy, Tarangini, Sandhu, Gurjinder, Tezera, Liku B., Thomas, Richard, Singhania, Akul, Woelk, Christopher H., Dimitrov, Borislav D., Agranoff, Dan, Evans, Carlton A. W., Friedland, Jon S., Elkington, Paul T.
Publicado 2015

OnPLS-Based Multi-Block Data Integration: A Multivariate Approach to Interrogating Biological Interactions in Asthma

por Reinke, Stacey N., Galindo-Prieto, Beatriz, Skotare, Tomas, Broadhurst, David I., Singhania, Akul, Horowitz, Daniel, Djukanović, Ratko, Hinks, Timothy S.C., Geladi, Paul, Trygg, Johan, Wheelock, Craig E.
Publicado 2018

The TCR repertoire of α-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse

por Singhania, Akul, Pham, John, Dhanwani, Rekha, Frazier, April, Rezende Dutra, Juliana, Marder, Karen S., Phillips, Elizabeth, Mallal, Simon, Amara, Amy W., Standaert, David G., Sulzer, David, Peters, Bjoern, Sette, Alessandro, Lindestam Arlehamn, Cecilia S.
Publicado 2021

CD4+CCR6+ T cells dominate the BCG-induced transcriptional signature

por Singhania, Akul, Dubelko, Paige, Kuan, Rebecca, Chronister, William D., Muskat, Kaylin, Das, Jyotirmoy, Phillips, Elizabeth J., Mallal, Simon A., Seumois, Grégory, Vijayanand, Pandurangan, Sette, Alessandro, Lerm, Maria, Peters, Bjoern, Lindestam Arlehamn, Cecilia
Publicado 2021

Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis

por Tabone, Olivier, Verma, Raman, Singhania, Akul, Chakravarty, Probir, Branchett, William J., Graham, Christine M., Lee, Jo, Trang, Tran, Reynier, Frederic, Leissner, Philippe, Kaiser, Karine, Rodrigue, Marc, Woltmann, Gerrit, Haldar, Pranabashis, O’Garra, Anne
Publicado 2021

A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection

por Singhania, Akul, Verma, Raman, Graham, Christine M., Lee, Jo, Tran, Trang, Richardson, Matthew, Lecine, Patrick, Leissner, Philippe, Berry, Matthew P. R., Wilkinson, Robert J., Kaiser, Karine, Rodrigue, Marc, Woltmann, Gerrit, Haldar, Pranabashis, O’Garra, Anne
Publicado 2018

Single-cell profiling reveals distinct subsets of CD14+ monocytes drive blood immune signatures of active tuberculosis

por Hillman, Hannah, Khan, Nabeela, Singhania, Akul, Dubelko, Paige, Soldevila, Ferran, Tippalagama, Rashmi, DeSilva, Aruna D., Gunasena, Bandu, Perera, Judy, Scriba, Thomas J., Ontong, Cynthia, Fisher, Michelle, Luabeya, Angelique, Taplitz, Randy, Seumois, Gregory, Vijayanand, Pandurangan, Hedrick, Catherine C., Peters, Bjoern, Burel, Julie G.
Publicado 2023

Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis

por Moreira-Teixeira, Lúcia, Tabone, Olivier, Graham, Christine M., Singhania, Akul, Stavropoulos, Evangelos, Redford, Paul S., Chakravarty, Probir, Priestnall, Simon L., Suarez-Bonnet, Alejandro, Herbert, Eleanor, Mayer-Barber, Katrin D., Sher, Alan, Fonseca, Kaori L., Sousa, Jeremy, Cá, Baltazar, Verma, Raman, Haldar, Pranabashis, Saraiva, Margarida, O’Garra, Anne
Publicado 2020

An In-Depth Comparison of Latent HIV-1 Reactivation in Multiple Cell Model Systems and Resting CD4+ T Cells from Aviremic Patients

por Spina, Celsa A., Anderson, Jenny, Archin, Nancie M., Bosque, Alberto, Chan, Jonathan, Famiglietti, Marylinda, Greene, Warner C., Kashuba, Angela, Lewin, Sharon R., Margolis, David M., Mau, Matthew, Ruelas, Debbie, Saleh, Suha, Shirakawa, Kotaro, Siliciano, Robert F., Singhania, Akul, Soto, Paula C., Terry, Valeri H., Verdin, Eric, Woelk, Christopher, Wooden, Stacey, Xing, Sifei, Planelles, Vicente
Publicado 2013

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

por Singhania, Akul, Graham, Christine M., Gabryšová, Leona, Moreira-Teixeira, Lúcia, Stavropoulos, Evangelos, Pitt, Jonathan M., Chakravarty, Probir, Warnatsch, Annika, Branchett, William J., Conejero, Laura, Lin, Jing-Wen, Davidson, Sophia, Wilson, Mark S., Bancroft, Gregory, Langhorne, Jean, Frickel, Eva, Sesay, Abdul K., Priestnall, Simon L., Herbert, Eleanor, Ioannou, Marianna, Wang, Qian, Humphreys, Ian R., Dodd, Jonathan, Openshaw, Peter J. M., Mayer-Barber, Katrin D., Jankovic, Dragana, Sher, Alan, Lloyd, Clare M., Baldwin, Nicole, Chaussabel, Damien, Papayannopoulos, Venizelos, Wack, Andreas, Banchereau, Jacques F., Pascual, Virginia M., O’Garra, Anne
Publicado 2019

CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition

por Gallo, David, Young, Jordan T. F., Fourtounis, Jimmy, Martino, Giovanni, Álvarez-Quilón, Alejandro, Bernier, Cynthia, Duffy, Nicole M., Papp, Robert, Roulston, Anne, Stocco, Rino, Szychowski, Janek, Veloso, Artur, Alam, Hunain, Baruah, Prasamit S., Fortin, Alexanne Bonneau, Bowlan, Julian, Chaudhary, Natasha, Desjardins, Jessica, Dietrich, Evelyne, Fournier, Sara, Fugère-Desjardins, Chloe, Goullet de Rugy, Theo, Leclaire, Marie-Eve, Liu, Bingcan, Bhaskaran, Vivek, Mamane, Yael, Melo, Henrique, Nicolas, Olivier, Singhania, Akul, Szilard, Rachel K., Tkáč, Ján, Yin, Shou Yun, Morris, Stephen J., Zinda, Michael, Marshall, C. Gary, Durocher, Daniel
Publicado 2022