β-Catenin Activation in Hepatocellular Cancer: Implications in Biology and Therapy

por Krutsenko, Yekaterina, Singhi, Aatur D., Monga, Satdarshan P.
Publicado 2021

Novel ALK Fusion, PPFIBP1-ALK, in Pancreatic Ductal Adenocarcinoma Responsive to Alectinib and Lorlatinib

por Gower, Arjan, Golestany, Barry, Gong, Jun, Singhi, Aatur D., Hendifar, Andrew Eugene
Publicado 2020

Rosai–Dorfman Disease (Sinus Histiocytosis with Massive Lymphadenopathy) of the Pancreas: Third Reported Occurrence

por Romero Arenas, Minerva A., Singhi, Aatur D., Hruban, Ralph H., Cameron, Andrew M.
Publicado 2012

An Unexpected Etiology of Pancreatic Panniculitis: A Case Report

por Evans, Anna C., Singhi, Aatur D., Zeh, Herbert J., Bahary, Nathan, Brand, Randall E.
Publicado 2017

Changes in beta-catenin expression and activation during progression of primary sclerosing cholangitis predict disease recurrence

por Ayers, Mary, Liu, Silvia, Singhi, Aatur D., Kosar, Karis, Cornuet, Pamela, Nejak-Bowen, Kari
Publicado 2022

RNA Sequencing Identifies Frequent Mitogen-activated Protein Kinase–associated Fusion Genes in Intraductal Tubulopapillary Neoplasms of the Pancreas

por LEE, JAE W., HRUBAN, RALPH H., BROSENS, LODEWIJK A.A., CONDELLO, VINCENZO, NIKIFOROVA, MARINA N., SINGHI, AATUR D.
Publicado 2023

Inhibition of endoplasmic-reticulum-stress-mediated autophagy enhances the effectiveness of chemotherapeutics on pancreatic cancer

por Thakur, Prakash C., Miller-Ocuin, Jennifer L., Nguyen, Khanh, Matsuda, Rina, Singhi, Aatur D., Zeh, Herbert J., Bahary, Nathan
Publicado 2018

Inhibition of the SLC35B2–TPST2 Axis of Tyrosine Sulfation Attenuates the Growth and Metastasis of Pancreatic Ductal Adenocarcinom

por Cai, Xinran, Li, Sihan, Zeng, Xuemei, Xu, Meishu, Wang, Zehua, Singhi, Aatur D., Tang, Daolin, Li, Song, Yates, Nathan A., Yang, Da, Xie, Wen
Publicado 2023

The CA19-9 and Sialyl-TRA Antigens Define Separate Subpopulations of Pancreatic Cancer Cells

por Barnett, Daniel, Liu, Ying, Partyka, Katie, Huang, Ying, Tang, Huiyuan, Hostetter, Galen, Brand, Randall E., Singhi, Aatur D., Drake, Richard R., Haab, Brian B.
Publicado 2017

DNA released from neutrophil extracellular traps (NETs) activates pancreatic stellate cells and enhances pancreatic tumor growth

por Miller-Ocuin, Jennifer L., Liang, Xiaoyan, Boone, Brian A., Doerfler, W. Reed, Singhi, Aatur D., Tang, Daolin, Kang, Rui, Lotze, Michael T., Zeh, Herbert J.
Publicado 2019

SMAD4 loss is associated with response to neoadjuvant chemotherapy plus hydroxychloroquine in patients with pancreatic adenocarcinoma

por Fei, Naomi, Wen, Sijin, Ramanathan, Rajesh, Hogg, Melissa E., Zureikat, Amer H., Lotze, Michael T., Bahary, Nathan, Singhi, Aatur D., Zeh, Herbert J., Boone, Brian A.
Publicado 2021

The Receptor for Advanced Glycation End Products (RAGE) Enhances Autophagy and Neutrophil Extracellular Traps in Pancreatic Cancer

por Boone, Brian A., Orlichenko, Lidiya, Schapiro, Nicole E., Loughran, Patricia, Gianfrate, Gianmarino C., Ellis, Jarrod T., Singhi, Aatur D., Kang, Rui, Tang, Daolin, Lotze, Michael T., Zeh, Herbert J.
Publicado 2015

Overweight or Obese Individuals at Eighteen Years of Age Develop Pancreatic Adenocarcinoma at a Significantly Earlier Age

por Chao, David T., Shah, Nilesh H., Zeh, Herbert J., Singhi, Aatur D., Bahary, Nathan, McGrath, Kevin M., Fasanella, Kenneth E., Zureikat, Amer H., Whitcomb, David C., Brand, Randall E.
Publicado 2018

MYC Gene Amplification is Often Acquired in Lethal Distant Breast Cancer Metastases of Unamplified Primary Tumors

por Singhi, Aatur D., Cimino-Mathews, Ashley, Jenkins, Robert B., Lan, Fusheng, Fink, Stephanie R., Nassar, Hind, Vang, Russell, Fetting, John, Hicks, Jessica, Sukumar, Saraswati, De Marzo, Angelo M., Argani, Pedram
Publicado 2011

Enhanced Neutrophil Extracellular Trap Formation in Acute Pancreatitis Contributes to Disease Severity and Is Reduced by Chloroquine

por Murthy, Pranav, Singhi, Aatur D., Ross, Mark A., Loughran, Patricia, Paragomi, Pedram, Papachristou, Georgios I., Whitcomb, David C., Zureikat, Amer H., Lotze, Michael T., Zeh III, Herbert J., Boone, Brian A.
Publicado 2019

Impact of genomic profiling on the treatment and outcomes of patients with advanced gastrointestinal malignancies

por Dhir, Mashaal, Choudry, Haroon A., Holtzman, Matthew P., Pingpank, James F., Ahrendt, Steven A., Zureikat, Amer H., Hogg, Melissa E., Bartlett, David L., Zeh, Herbert J., Singhi, Aatur D., Bahary, Nathan
Publicado 2016

Adaptive Dynamic Therapy and Survivorship for Operable Pancreatic Cancer

por AlMasri, Samer, Zenati, Mazen, Hammad, Abdulrahman, Nassour, Ibrahim, Liu, Hao, Hogg, Melissa E., Zeh, Herbert J., Boone, Brian, Bahary, Nathan, Singhi, Aatur D., Lee, Kenneth K., Paniccia, Alessandro, Zureikat, Amer H.
Publicado 2022

Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance

por Belmonte, Frances R., Dedousis, Nikolaos, Sipula, Ian, Desai, Nikita A., Singhi, Aatur D., Chu, Yanxia, Zhang, Yingze, Bannwarth, Sylvie, Paquis-Flucklinger, Véronique, Harrington, Lea, Shiva, Sruti, Jurczak, Michael J., O’Doherty, Robert M., Kaufman, Brett A.
Publicado 2019

Encouraging long‐term survival following autophagy inhibition using neoadjuvant hydroxychloroquine and gemcitabine for high‐risk patients with resectable pancreatic carcinoma

por AlMasri, Samer S., Zenati, Mazen S., Desilva, Annissa, Nassour, Ibrahim, Boone, Brian A., Singhi, Aatur D., Bartlett, David L., Liotta, Lance A., Espina, Virginia, Loughran, Patricia, Lotze, Michael T., Paniccia, Alessandro, Zeh, Herbert J., Zureikat, Amer H., Bahary, Nathan
Publicado 2021

Fibrosis resolution in the mouse liver: Role of Mmp12 and potential role of calpain 1/2

por Sato, Toshifumi, Head, Kimberly Z., Li, Jiang, Dolin, Christine E., Wilkey, Daniel, Skirtich, Nolan, Smith, Katelyn, McCreary, Dylan D., Liu, Sylvia, Beier, Juliane I., Singhi, Aatur D., McEnaney, Ryan M., Merchant, Michael L., Arteel, Gavin E.
Publicado 2022