Zoledronic Acid Targeting of the Mevalonate Pathway Causes Reduced Cell Recruitment and Attenuates Pulmonary Fibrosis

por Tanner, Lloyd, Bergwik, Jesper, Single, Andrew B., Bhongir, Ravi K. V., Erjefält, Jonas S., Egesten, Arne
Publicado 2022

A high-throughput screen to identify novel synthetic lethal compounds for the treatment of E-cadherin-deficient cells

por Beetham, Henry, Chen, Augustine, Telford, Bryony J., Single, Andrew, Jarman, Kate E., Lackovic, Kurt, Luxenburger, Andreas, Guilford, Parry
Publicado 2019

Allosteric AKT Inhibitors Target Synthetic Lethal Vulnerabilities in E-Cadherin-Deficient Cells

por Bougen-Zhukov, Nicola, Nouri, Yasmin, Godwin, Tanis, Taylor, Megan, Hakkaart, Christopher, Single, Andrew, Brew, Tom, Permina, Elizabeth, Chen, Augustine, Black, Michael A., Guilford, Parry
Publicado 2019

E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function

por Godwin, Tanis D., Kelly, S. Thomas, Brew, Tom P., Bougen-Zhukov, Nicola M., Single, Andrew B., Chen, Augustine, Stylianou, Cassie E., Harris, Lawrence D., Currie, Sophie K., Telford, Bryony J., Beetham, Henry G., Evans, Gary B., Black, Michael A., Guilford, Parry J.
Publicado 2018