The Birth of the Modern Era of Parkinson’s Disease Genetics

por Singleton, Andrew B., Hardy, John A., Gasser, Thomas
Publicado 2017

LRRK2: Cause, Risk, and Mechanism

por Paisán-Ruiz, Coro, Lewis, Patrick A., Singleton, Andrew B.
Publicado 2013

Genetic players in multiple system atrophy: unfolding the nature of the beast

por Stemberger, Sylvia, Scholz, Sonja W., Singleton, Andrew B., Wenning, Gregor K.
Publicado 2011

Exome sequencing expands the mutational spectrum of SPG8 in a family with spasticity responsive to l-DOPA treatment

por Bettencourt, Conceição, Morris, Huw R., Singleton, Andrew B., Hardy, John, Houlden, Henry
Publicado 2013

A common genetic factor for Parkinson disease in ethnic Chinese population in Taiwan

por Fung, Hon-Chung, Chen, Chiung-Mei, Hardy, John, Singleton, Andrew B, Wu, Yih-Ru
Publicado 2006

Cell population-specific expression analysis of human cerebellum

por Kuhn, Alexandre, Kumar, Azad, Beilina, Alexandra, Dillman, Allissa, Cookson, Mark R, Singleton, Andrew B
Publicado 2012

Variant biomarker discovery using mass spectrometry-based proteogenomics

por Reilly, Luke, Seddighi, Sahba, Singleton, Andrew B., Cookson, Mark R., Ward, Michael E., Qi, Yue A.
Publicado 2023

Genome Wide Assessment of Young Onset Parkinson’s Disease from Finland

por Hernandez, Dena G., Nalls, Michael A., Ylikotila, Pauli, Keller, Margaux, Hardy, John A., Majamaa, Kari, Singleton, Andrew B.
Publicado 2012

Human brain single nucleus cell type enrichments in neurodegenerative diseases

por Alvarado, Chelsea X, Weller, Cory A., Johnson, Nicholas, Leonard, Hampton L., Singleton, Andrew B., Reed, Xylena, Blauewendraat, Cornelis, Nalls, Mike A
Publicado 2023

A Novel DYT-5 Mutation with Phenotypic Variability within a Colombian Family

por Bernal-Pacheco, Oscar, Oyama, Genko, Briton, Angela, Singleton, Andrew B., Fernandez, Hubert H., Rodriguez, Ramon L., Malaty, Irene A., Okun, Michael S.
Publicado 2013

Finnish Parkinson’s disease study integrating protein-protein interaction network data with exome sequencing analysis

por Siitonen, Ari, Kytövuori, Laura, Nalls, Mike A., Gibbs, Raphael, Hernandez, Dena G., Ylikotila, Pauli, Peltonen, Markku, Singleton, Andrew B., Majamaa, Kari
Publicado 2019

A population scale analysis of rare SNCA variation in the UK Biobank

por Blauwendraat, Cornelis, Makarious, Mary B., Leonard, Hampton L., Bandres-Ciga, Sara, Iwaki, Hirotaka, Nalls, Mike A., Noyce, Alastair J., Singleton, Andrew B.
Publicado 2020

Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk

por Lake, Julie, Reed, Xylena, Langston, Rebekah G., Nalls, Mike A., Gan‐Or, Ziv, Cookson, Mark R., Singleton, Andrew B., Blauwendraat, Cornelis, Leonard, Hampton L.
Publicado 2021

Lack of evidence for a genetic association between FGF20 and Parkinson's disease in Finnish and Greek patients

por Clarimon, Jordi, Xiromerisiou, Georgia, Eerola, Johanna, Gourbali, Vanesa, Hellström, Olli, Dardiotis, Euthimios, Peuralinna, Terhi, Papadimitriou, Alexandros, Hadjigeorgiou, George M, Tienari, Pentti J, Singleton, Andrew B
Publicado 2005

FTO Genotype and Aging: Pleiotropic Longitudinal Effects on Adiposity, Brain function, Impulsivity and Diet

por Chuang, Yi-Fang, Tanaka, Toshiko, Beason-Held, Lori L., An, Yang, Terracciano, Antonio, Sutin, Angelina R., Kraut, Michael, Singleton, Andrew B., Resnick, Susan M., Thambisetty, Madhav
Publicado 2014

Transcriptomic profiling of the human brain reveals that altered synaptic gene expression is associated with chronological aging

por Dillman, Allissa A., Majounie, Elisa, Ding, Jinhui, Gibbs, J. Raphael, Hernandez, Dena, Arepalli, Sampath, Traynor, Bryan J., Singleton, Andrew B., Galter, Dagmar, Cookson, Mark R.
Publicado 2017

Functionalization of the TMEM175 p.M393T variant as a risk factor for Parkinson disease

por Jinn, Sarah, Blauwendraat, Cornelis, Toolan, Dawn, Gretzula, Cheryl A, Drolet, Robert E, Smith, Sean, Nalls, Mike A, Marcus, Jacob, Singleton, Andrew B, Stone, David J
Publicado 2019

Unhealthy Behaviours and Risk of Parkinson’s Disease: A Mendelian Randomisation Study

por Heilbron, Karl, Jensen, Melanie P., Bandres-Ciga, Sara, Fontanillas, Pierre, Blauwendraat, Cornelis, Nalls, Mike A., Singleton, Andrew B., Smith, George Davey, Cannon, Paul, Noyce, Alastair J.
Publicado 2021

Parkinson’s Disease Case Ascertainment in the Sister Study: A Cohort for Environmental Health Research

por Cao, Zichun, Song, Shengfang, Huang, Xuemei, Li, Chenxi, Luo, Zhehui, D’Aloisio, Aimee A., Suarez, Lourdes, Hernandez, Dena G., Singleton, Andrew B., Sandler, Dale P., Chen, Honglei
Publicado 2023

Polygenic risk of Parkinson disease is correlated with disease age at onset

por Escott‐Price, Valentina, Nalls, Mike A., Morris, Huw R., Lubbe, Steven, Brice, Alexis, Gasser, Thomas, Heutink, Peter, Wood, Nicholas W., Hardy, John, Singleton, Andrew B., Williams, Nigel M.
Publicado 2015