In vitro breast cancer models for studying mechanisms of resistance to endocrine therapy

por Cheng, Gary J., Leung, Euphemia Y., Singleton, Dean C.
Publicado 2022

Bystander or No Bystander for Gene Directed Enzyme Prodrug Therapy

por Dachs, Gabi U., Hunt, Michelle A., Syddall, Sophie, Singleton, Dean C., Patterson, Adam V.
Publicado 2009

Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer

por Singleton, Dean C., Dechaume, Anne-Lise, Murray, Pamela M., Katt, William P., Baguley, Bruce C., Leung, Euphemia Y.
Publicado 2020

Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis

por Singleton, Dean C., Rouhi, Pegah, Zois, Christos E., Haider, Syed, Li, Ji-Liang, Kessler, Benedikt M., Cao, Yihai, Harris, Adrian L.
Publicado 2014

Patient-Derived Xenograft and Organoid Models for Precision Medicine Targeting of the Tumour Microenvironment in Head and Neck Cancer

por Lee, Tet Woo, Lai, Amy, Harms, Julia K., Singleton, Dean C., Dickson, Benjamin D., Macann, Andrew M. J., Hay, Michael P., Jamieson, Stephen M. F.
Publicado 2020

N -Methyl-D-Aspartate Receptor Hypofunction in Meg-01 Cells Reveals a Role for Intracellular Calcium Homeostasis in Balancing Megakaryocytic-Erythroid Differentiation

por Hearn, James I., Green, Taryn N., Chopra, Martin, Nursalim, Yohanes N. S., Ladvanszky, Leandro, Knowlton, Nicholas, Blenkiron, Cherie, Poulsen, Raewyn C., Singleton, Dean C., Bohlander, Stefan K., Kalev-Zylinska, Maggie L.
Publicado 2020

Derivation of Breast Cancer Cell Lines Under Physiological (5%) Oxygen Concentrations

por Leung, Euphemia Y., Askarian-Amiri, Marjan E., Singleton, Dean C., Ferraro-Peyret, Carole, Joseph, Wayne R., Finlay, Graeme J., Broom, Reuben J., Kakadia, Purvi M., Bohlander, Stefan K., Marshall, Elaine, Baguley, Bruce C.
Publicado 2018

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor**

por Clark, Peter G K, Vieira, Lucas C C, Tallant, Cynthia, Fedorov, Oleg, Singleton, Dean C, Rogers, Catherine M, Monteiro, Octovia P, Bennett, James M, Baronio, Roberta, Müller, Susanne, Daniels, Danette L, Méndez, Jacqui, Knapp, Stefan, Brennan, Paul E, Dixon, Darren J
Publicado 2015

LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor

por Clark, Peter G. K., Vieira, Lucas C. C., Tallant, Cynthia, Fedorov, Oleg, Singleton, Dean C., Rogers, Catherine M., Monteiro, Octovia P., Bennett, James M., Baronio, Roberta, Müller, Susanne, Daniels, Danette L., Méndez, Jacqui, Knapp, Stefan, Brennan, Paul E., Dixon, Darren J.
Publicado 2015

Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains

por Hay, Duncan A., Fedorov, Oleg, Martin, Sarah, Singleton, Dean C., Tallant, Cynthia, Wells, Christopher, Picaud, Sarah, Philpott, Martin, Monteiro, Octovia P., Rogers, Catherine M., Conway, Stuart J., Rooney, Timothy P. C., Tumber, Anthony, Yapp, Clarence, Filippakopoulos, Panagis, Bunnage, Mark E., Müller, Susanne, Knapp, Stefan, Schofield, Christopher J., Brennan, Paul E.
Publicado 2014