Efficacy of Human Exposures of Gepotidacin (GSK2140944) against Escherichia coli in a Rat Pyelonephritis Model

por Hoover, Jennifer L., Singley, Christine M., Elefante, Philippa, Rittenhouse, Stephen
Publicado 2019

Reducing Antibacterial Development Risk for GSK1322322 by Exploring Potential Human Dose Regimens in Nonclinical Efficacy Studies Using Immunocompetent Rats

por Hoover, Jennifer L., Singley, Christine M., Elefante, Philippa, DeMarsh, Peter, Zalacain, Magdalena, Rittenhouse, Stephen
Publicado 2017

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

por Hoover, Jennifer L., Lewandowski, Thomas F., Mininger, Cindy L., Singley, Christine M., Sucoloski, Scott, Rittenhouse, Stephen
Publicado 2017

Efficacy of Cefiderocol against Carbapenem-Resistant Gram-Negative Bacilli in Immunocompetent-Rat Respiratory Tract Infection Models Recreating Human Plasma Pharmacokinetics

por Matsumoto, Shuhei, Singley, Christine M., Hoover, Jennifer, Nakamura, Rio, Echols, Roger, Rittenhouse, Stephen, Tsuji, Masakatsu, Yamano, Yoshinori
Publicado 2017