Intratracheal aerosolization of viral vectors to newborn pig airways

por Cooney, Ashley L, Sinn, Patrick L
Publicado 2020

Cystic Fibrosis Gene Therapy: Looking Back, Looking Forward

por Cooney, Ashley L., McCray, Paul B., Sinn, Patrick L.
Publicado 2018

Intrapulmonary Versus Nasal Transduction of Murine Airways With GP64-pseudotyped Viral Vectors

por Oakland, Mayumi, Maury, Wendy, McCray, Paul B, Sinn, Patrick L
Publicado 2013

Measles Virus Ribonucleoprotein Complexes Rapidly Spread across Well-Differentiated Primary Human Airway Epithelial Cells along F-Actin Rings

por Singh, Brajesh K., Pfaller, Christian K., Cattaneo, Roberto, Sinn, Patrick L.
Publicado 2019

Extracellular Vesicle-Mediated siRNA Delivery, Protein Delivery, and CFTR Complementation in Well-Differentiated Human Airway Epithelial Cells

por Singh, Brajesh K., Cooney, Ashley L., Krishnamurthy, Sateesh, Sinn, Patrick L.
Publicado 2020

Enhanced Tropism of Species B1 Adenoviral-Based Vectors for Primary Human Airway Epithelial Cells

por Li, Ni, Cooney, Ashley L., Zhang, Wenli, Ehrhardt, Anja, Sinn, Patrick L.
Publicado 2019

Gene Therapy Potential for Genetic Disorders of Surfactant Dysfunction

por Cooney, Ashley L., Wambach, Jennifer A., Sinn, Patrick L., McCray, Paul B.
Publicado 2022

Lentiviral vectors transduce lung stem cells without disrupting plasticity

por Cooney, Ashley L., Thurman, Andrew L., McCray, Paul B., Pezzulo, Alejandro A., Sinn, Patrick L.
Publicado 2021

Interferon-independent processes constrain measles virus cell-to-cell spread in primary human airway epithelial cells

por Durnell, Lorellin A., Hippee, Camilla E., Cattaneo, Roberto, Bartlett, Jennifer A., Singh, Brajesh K., Sinn, Patrick L.
Publicado 2023

piggyBac-mediated phenotypic correction of factor VIII deficiency

por Staber, Janice M, Pollpeter, Molly J, Arensdorf, Angela, Sinn, Patrick L, Rutkowski, D Thomas, McCray, Paul B
Publicado 2014

Measles virus exits human airway epithelia within dislodged metabolically active infectious centers

por Hippee, Camilla E., Singh, Brajesh K., Thurman, Andrew L., Cooney, Ashley L., Pezzulo, Alejandro A., Cattaneo, Roberto, Sinn, Patrick L.
Publicado 2021

Increased CFTR expression and function from an optimized lentiviral vector for cystic fibrosis gene therapy

por Marquez Loza, Laura I., Cooney, Ashley L., Dong, Qian, Randak, Christoph O., Rivella, Stefano, Sinn, Patrick L., McCray, Paul B.
Publicado 2021

Lentiviral Vector Gene Transfer to Porcine Airways

por Sinn, Patrick L, Cooney, Ashley L, Oakland, Mayumi, Dylla, Douglas E, Wallen, Tanner J, Pezzulo, Alejandro A, Chang, Eugene H, McCray, Paul B
Publicado 2012

Functional correction of CFTR mutations in human airway epithelial cells using adenine base editors

por Krishnamurthy, Sateesh, Traore, Soumba, Cooney, Ashley L, Brommel, Christian M, Kulhankova, Katarina, Sinn, Patrick L, Newby, Gregory A, Liu, David R, McCray, Paul B
Publicado 2021

WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia

por Rehman, Tayyab, Karp, Philip H., Thurman, Andrew L., Mather, Steven E., Jain, Akansha, Cooney, Ashley L., Sinn, Patrick L., Pezzulo, Alejandro A., Duffey, Michael E., Welsh, Michael J.
Publicado 2022

Integrin α6β4 Identifies Human Distal Lung Epithelial Progenitor Cells with Potential as a Cell-Based Therapy for Cystic Fibrosis Lung Disease

por Li, Xiaopeng, Rossen, Nathan, Sinn, Patrick L., Hornick, Andrew L., Steines, Benjamin R., Karp, Philip H., Ernst, Sarah E., Adam, Ryan J., Moninger, Thomas O., Levasseur, Dana N., Zabner, Joseph
Publicado 2013

CFTR-rich ionocytes mediate chloride absorption across airway epithelia

por Lei, Lei, Traore, Soumba, Romano Ibarra, Guillermo S., Karp, Philip H., Rehman, Tayyab, Meyerholz, David K., Zabner, Joseph, Stoltz, David A., Sinn, Patrick L., Welsh, Michael J., McCray, Paul B., Thornell, Ian M.
Publicado 2023

Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus

por Cooney, Ashley L, Singh, Brajesh K, Loza, Laura Marquez, Thornell, Ian M, Hippee, Camilla E, Powers, Linda S, Ostedgaard, Lynda S, Meyerholz, David K, Wohlford-Lenane, Chris, Stoltz, David A, B. McCray, Paul, Sinn, Patrick L
Publicado 2018

Adherens junction protein nectin-4 (PVRL4) is the epithelial receptor for measles virus

por Mühlebach, Michael D., Mateo, Mathieu, Sinn, Patrick L., Prüfer, Steffen, Uhlig, Katharina M., Leonard, Vincent H. J., Navaratnarajah, Chanakha K., Frenzke, Marie, Wong, Xiao X., Sawatsky, Bevan, Ramachandran, Shyam, McCray, Paul B., Cichutek, Klaus, von Messling, Veronika, Lopez, Marc, Cattaneo, Roberto
Publicado 2011