Molecular mechanisms of amyloid formation in living systems

por Sinnige, Tessa
Publicado 2022

Membrane-Catalyzed Aggregation of Islet Amyloid Polypeptide Is Dominated by Secondary Nucleation

por Elenbaas, Barend O. W., Khemtemourian, Lucie, Killian, J. Antoinette, Sinnige, Tessa
Publicado 2022

Formation of the β-barrel assembly machinery complex in lipid bilayers as seen by solid-state NMR

por Pinto, Cecilia, Mance, Deni, Sinnige, Tessa, Daniëls, Mark, Weingarth, Markus, Baldus, Marc
Publicado 2018

Expression of the amyloid-β peptide in a single pair of C. elegans sensory neurons modulates the associated behavioural response

por Sinnige, Tessa, Ciryam, Prashanth, Casford, Samuel, Dobson, Christopher M., de Bono, Mario, Vendruscolo, Michele
Publicado 2019

An Efficient Labelling Approach to Harness Backbone and Side-Chain Protons in (1)H-Detected Solid-State NMR Spectroscopy

por Mance, Deni, Sinnige, Tessa, Kaplan, Mohammed, Narasimhan, Siddarth, Daniëls, Mark, Houben, Klaartje, Baldus, Marc, Weingarth, Markus
Publicado 2015

Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in C. elegans

por Sinnige, Tessa, Meisl, Georg, Michaels, Thomas C. T., Vendruscolo, Michele, Knowles, Tuomas P. J., Morimoto, Richard I.
Publicado 2021

Combined (1)H-Detected Solid-State NMR Spectroscopy and Electron Cryotomography to Study Membrane Proteins across Resolutions in Native Environments

por Baker, Lindsay A., Sinnige, Tessa, Schellenberger, Pascale, de Keyzer, Jeanine, Siebert, C. Alistair, Driessen, Arnold J.M., Baldus, Marc, Grünewald, Kay
Publicado 2018

Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans

por Huang, Chaolie, Wagner-Valladolid, Sara, Stephens, Amberley D, Jung, Raimund, Poudel, Chetan, Sinnige, Tessa, Lechler, Marie C, Schlörit, Nicole, Lu, Meng, Laine, Romain F, Michel, Claire H, Vendruscolo, Michele, Kaminski, Clemens F, Kaminski Schierle, Gabriele S, David, Della C
Publicado 2019

Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease

por Perni, Michele, van der Goot, Annemieke, Limbocker, Ryan, van Ham, Tjakko J., Aprile, Francesco A., Xu, Catherine K., Flagmeier, Patrick, Thijssen, Karen, Sormanni, Pietro, Fusco, Giuliana, Chen, Serene W., Challa, Pavan K., Kirkegaard, Julius B., Laine, Romain F., Ma, Kai Yu, Müller, Martin B. D., Sinnige, Tessa, Kumita, Janet R., Cohen, Samuel I. A., Seinstra, Renée, Kaminski Schierle, Gabriele S., Kaminski, Clemens F., Barbut, Denise, De Simone, Alfonso, Knowles, Tuomas P. J., Zasloff, Michael, Nollen, Ellen A. A., Vendruscolo, Michele, Dobson, Christopher M.
Publicado 2021