Metabolic control of gene transcription in non-alcoholic fatty liver disease: the role of the epigenome

por Sinton, Matthew C., Hay, David C., Drake, Amanda J.
Publicado 2019

The Influence of Sex Hormones in Liver Function and Disease

por Kasarinaite, Alvile, Sinton, Matthew, Saunders, Philippa T. K., Hay, David C.
Publicado 2023

Modelling host- Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids

por Chandrasegaran, Praveena, Nabilla Lestari, Agatha, Sinton, Matthew C., Gopalakrishnan, Jay, Quintana, Juan F.
Publicado 2023

Modeling human hepatic steatosis in pluripotent stem cell-derived hepatocytes

por Sinton, Matthew C., Meseguer-Ripolles, Jose, Lucendo-Villarin, Baltasar, Drake, Amanda J., Hay, David C.
Publicado 2021

Altered hypothalamic DNA methylation and stress-induced hyperactivity following early life stress

por Fitzgerald, Eamon, Sinton, Matthew C., Wernig-Zorc, Sara, Morton, Nicholas M., Holmes, Megan C., Boardman, James P., Drake, Amanda J.
Publicado 2021

Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection

por Quintana, Juan F., Chandrasegaran, Praveena, Sinton, Matthew C., Briggs, Emma M., Otto, Thomas D., Heslop, Rhiannon, Bentley-Abbot, Calum, Loney, Colin, de Lecea, Luis, Mabbott, Neil A., MacLeod, Annette
Publicado 2022

γδ T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection

por Quintana, Juan F., Sinton, Matthew C., Chandrasegaran, Praveena, Lestari, Agatha Nabilla, Heslop, Rhiannon, Cheaib, Bachar, Ogunsola, John, Ngoyi, Dieudonne Mumba, Kuispond Swar, Nono-Raymond, Cooper, Anneli, Mabbott, Neil A., Coffelt, Seth B., MacLeod, Annette
Publicado 2023

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection

por Sinton, Matthew C., Chandrasegaran, Praveena R. G., Capewell, Paul, Cooper, Anneli, Girard, Alex, Ogunsola, John, Perona-Wright, Georgia, M Ngoyi, Dieudonné, Kuispond, Nono, Bucheton, Bruno, Camara, Mamadou, Kajimura, Shingo, Bénézech, Cécile, Mabbott, Neil A., MacLeod, Annette, Quintana, Juan F.
Publicado 2023

A human pluripotent stem cell model for the analysis of metabolic dysfunction in hepatic steatosis

por Sinton, Matthew C., Meseguer-Ripolles, Jose, Lucendo-Villarin, Baltasar, Wernig-Zorc, Sara, Thomson, John P., Carter, Roderick N., Lyall, Marcus J., Walker, Paul D., Thakker, Alpesh, Meehan, Richard R., Lavery, Gareth G., Morton, Nicholas M., Ludwig, Christian, Tennant, Daniel A., Hay, David C., Drake, Amanda J.
Publicado 2020

Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis

por Suchacki, Karla J., Tavares, Adriana A. S., Mattiucci, Domenico, Scheller, Erica L., Papanastasiou, Giorgos, Gray, Calum, Sinton, Matthew C., Ramage, Lynne E., McDougald, Wendy A., Lovdel, Andrea, Sulston, Richard J., Thomas, Benjamin J., Nicholson, Bonnie M., Drake, Amanda J., Alcaide-Corral, Carlos J., Said, Diana, Poloni, Antonella, Cinti, Saverio, Macpherson, Gavin J., Dweck, Marc R., Andrews, Jack P. M., Williams, Michelle C., Wallace, Robert J., van Beek, Edwin J. R., MacDougald, Ormond A., Morton, Nicholas M., Stimson, Roland H., Cawthorn, William P.
Publicado 2020