Location, Location, Location: Five Facts about Tissue Tropism and Pathogenesis

por McCall, Laura-Isobel, Siqueira-Neto, Jair L., McKerrow, James H.
Publicado 2016

Enantioselective inhibition of the SARS-CoV-2 main protease with rhenium(i) picolinic acid complexes

por Karges, Johannes, Giardini, Miriam A., Blacque, Olivier, Woodworth, Brendon, Siqueira-Neto, Jair L., Cohen, Seth M.
Publicado 2022

Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome

por McCall, Laura-Isobel, Tripathi, Anupriya, Vargas, Fernando, Knight, Rob, Dorrestein, Pieter C., Siqueira-Neto, Jair L.
Publicado 2018

Antimalarial drug discovery: progress and approaches

por Siqueira-Neto, Jair L, Wicht, Kathryn J., Chibale, Kelly, Burrows, Jeremy N., Fidock, David A., Winzeler, Elizabeth A.
Publicado 2023

Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi

por Shiratsubaki, Isabel S., Fang, Xin, Souza, Rodolpho O. O., Palsson, Bernhard O., Silber, Ariel M., Siqueira-Neto, Jair L.
Publicado 2020

Mechanism of Action of Methotrexate Against Zika Virus

por Beck, Sungjun, Zhu, Zhe, Oliveira, Michelli F., Smith, Davey M., Rich, Jeremy N., Bernatchez, Jean A., Siqueira-Neto, Jair L.
Publicado 2019

High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for Trypanosoma cruzi

por Bernatchez, Jean A., Chen, Emily, Hull, Mitchell V., McNamara, Case W., McKerrow, James H., Siqueira-Neto, Jair L.
Publicado 2020

Long term follow-up of Trypanosoma cruzi infection and Chagas disease manifestations in mice treated with benznidazole or posaconazole

por Calvet, Claudia Magalhães, Silva, Tatiana Araújo, Thomas, Diane, Suzuki, Brian, Hirata, Ken, Siqueira-Neto, Jair Lage, McKerrow, James H.
Publicado 2020

Spatial metabolomics identifies localized chemical changes in heart tissue during chronic cardiac Chagas Disease

por Dean, Danya A., Gautham, Gautham, Siqueira-Neto, Jair L., McKerrow, James H., Dorrestein, Pieter C., McCall, Laura-Isobel
Publicado 2021

An Image-Based Algorithm for Precise and Accurate High Throughput Assessment of Drug Activity against the Human Parasite Trypanosoma cruzi

por Moon, Seunghyun, Siqueira-Neto, Jair L., Moraes, Carolina Borsoi, Yang, Gyongseon, Kang, Myungjoo, Freitas-Junior, Lucio H., Hansen, Michael A. E.
Publicado 2014

Cysteine proteases in protozoan parasites

por Siqueira-Neto, Jair L., Debnath, Anjan, McCall, Laura-Isobel, Bernatchez, Jean A., Ndao, Momar, Reed, Sharon L., Rosenthal, Philip J.
Publicado 2018

Palstimolide A: A Complex Polyhydroxy Macrolide with Antiparasitic Activity

por Keller, Lena, Siqueira-Neto, Jair L., Souza, Julia M., Eribez, Korina, LaMonte, Gregory M., Smith, Jennifer E., Gerwick, William H.
Publicado 2020

Molecular dissection of Chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways

por Wozniak, Jacob M., Silva, Tatiana Araújo, Thomas, Diane, Siqueira-Neto, Jair L., McKerrow, James H., Gonzalez, David J., Calvet, Claudia M.
Publicado 2020

Dysregulation of Glycerophosphocholines in the Cutaneous Lesion Caused by Leishmania major in Experimental Murine Models

por Parab, Adwaita R., Thomas, Diane, Lostracco-Johnson, Sharon, Siqueira-Neto, Jair L., McKerrow, James H., Dorrestein, Pieter C., McCall, Laura-Isobel
Publicado 2021

Open drug discovery for the Zika virus

por Ekins, Sean, Mietchen, Daniel, Coffee, Megan, Stratton, Thomas P, Freundlich, Joel S, Freitas-Junior, Lucio, Muratov, Eugene, Siqueira-Neto, Jair, Williams, Antony J, Andrade, Carolina
Publicado 2016

Human iPSC-Derived 2D and 3D Platforms for Rapidly Assessing Developmental, Functional, and Terminal Toxicities in Neural Cells

por Slavin, Ileana, Dea, Steven, Arunkumar, Priyanka, Sodhi, Neha, Montefusco, Sandro, Siqueira-Neto, Jair, Seelke, Janet, Lofstrom, Mary Anne, Anson, Blake, Zanella, Fabian, Carromeu, Cassiano
Publicado 2021

An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages

por Siqueira-Neto, Jair L., Moon, Seunghyun, Jang, Jiyeon, Yang, Gyongseon, Lee, Changbok, Moon, Hong Kee, Chatelain, Eric, Genovesio, Auguste, Cechetto, Jonathan, Freitas-Junior, Lucio H.
Publicado 2012

High Throughput and Computational Repurposing for Neglected Diseases

por Hernandez, Helen W., Soeung, Melinda, Zorn, Kimberley M., Ashoura, Norah, Mottin, Melina, Andrade, Carolina Horta, Caffrey, Conor R., de Siqueira-Neto, Jair Lage, Ekins, Sean
Publicado 2018

Automated Nuclear Analysis of Leishmania major Telomeric Clusters Reveals Changes in Their Organization during the Parasite's Life Cycle

por Dossin, Fernando de M., Dufour, Alexandre, Dusch, Elodie, Siqueira-Neto, Jair L., Moraes, Carolina B., Yang, Gyong Seon, Cano, Maria Isabel, Genovesio, Auguste, Freitas-Junior, Lucio H.
Publicado 2008

The Leishmania amazonensis TRF (TTAGGG repeat-binding factor) homologue binds and co-localizes with telomeres

por da Silva, Marcelo S, Perez, Arina M, da Silveira, Rita de Cássia V, de Moraes, Camila E, Siqueira-Neto, Jair L, Freitas, Lucio de H, Cano, Maria Isabel N
Publicado 2010