Nod-Like Receptors: Cytosolic Watchdogs for Immunity against Pathogens

por Sirard, Jean-Claude, Vignal, Cécile, Dessein, Rodrigue, Chamaillard, Mathias
Publicado 2007

Synthetic gene-regulatory networks in the opportunistic human pathogen Streptococcus pneumoniae

por Sorg, Robin A., Gallay, Clement, Van Maele, Laurye, Sirard, Jean-Claude, Veening, Jan-Willem
Publicado 2020

A Model-Based Pharmacokinetic/Pharmacodynamic Analysis of the Combination of Amoxicillin and Monophosphoryl Lipid A Against S. pneumoniae in Mice

por Franck, Sebastian, Michelet, Robin, Casilag, Fiordiligie, Sirard, Jean-Claude, Wicha, Sebastian G., Kloft, Charlotte
Publicado 2021

Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner

por Errea, Agustina, Cayet, Delphine, Marchetti, Philippe, Tang, Cong, Kluza, Jerome, Offermanns, Stefan, Sirard, Jean-Claude, Rumbo, Martin
Publicado 2016

Therapeutic Synergy Between Antibiotics and Pulmonary Toll-Like Receptor 5 Stimulation in Antibiotic-Sensitive or -Resistant Pneumonia

por Matarazzo, Laura, Casilag, Fiordiligie, Porte, Rémi, Wallet, Frederic, Cayet, Delphine, Faveeuw, Christelle, Carnoy, Christophe, Sirard, Jean-Claude
Publicado 2019

A Key Role of Dendritic Cells in Probiotic Functionality

por Foligne, Benoit, Zoumpopoulou, Georgia, Dewulf, Joelle, Ben Younes, Amena, Chareyre, Fabrice, Sirard, Jean-Claude, Pot, Bruno, Grangette, Corinne
Publicado 2007

Transgenic Mouse Model Harboring the Transcriptional Fusion Ccl20-Luciferase as a Novel Reporter of Pro-Inflammatory Response

por Crispo, Martina, Van Maele, Laurye, Tabareau, Julien, Cayet, Delphine, Errea, Agustina, Ferreira, Ana María, Rumbo, Martin, Sirard, Jean Claude
Publicado 2013

Amoxicillin-resistant Streptococcus pneumoniae can be resensitized by targeting the mevalonate pathway as indicated by sCRilecs-seq

por Dewachter, Liselot, Dénéréaz, Julien, Liu, Xue, de Bakker, Vincent, Costa, Charlotte, Baldry, Mara, Sirard, Jean-Claude, Veening, Jan-Willem
Publicado 2022

IL-17A/F-Signaling Does Not Contribute to the Initial Phase of Mucosal Inflammation Triggered by S. Typhimurium

por Songhet, Pascal, Barthel, Manja, Röhn, Till A., Van Maele, Laurye, Cayet, Delphine, Sirard, Jean-Claude, Bachmann, Martin, Kopf, Manfred, Hardt, Wolf-Dietrich
Publicado 2010

The Toll-Like Receptor 5 agonist flagellin prevents Non-typeable Haemophilus influenzae-induced infection in cigarette smoke-exposed mice

por Pérez-Cruz, Magdiel, Koné, Bachirou, Porte, Rémi, Carnoy, Christophe, Tabareau, Julien, Gosset, Pierre, Trottein, François, Sirard, Jean-Claude, Pichavant, Muriel, Gosset, Philippe
Publicado 2021

Pseudomonas aeruginosa LasB Subverts Alveolar Macrophage Activity by Interfering With Bacterial Killing Through Downregulation of Innate Immune Defense, Reactive Oxygen Species Gen...

por Bastaert, Fabien, Kheir, Saadé, Saint-Criq, Vinciane, Villeret, Bérengère, Dang, Pham My-Chan, El-Benna, Jamel, Sirard, Jean-Claude, Voulhoux, Romé, Sallenave, Jean-Michel
Publicado 2018

Sustained desensitization to bacterial Toll-like receptor ligands after resolutionof respiratory influenza infection

por Didierlaurent, Arnaud, Goulding, John, Patel, Seema, Snelgrove, Robert, Low, Lionel, Bebien, Magali, Lawrence, Toby, van Rijt, Leonie S., Lambrecht, Bart N., Sirard, Jean-Claude, Hussell, Tracy
Publicado 2008

Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection

por Qin, Wanhai, Brands, Xanthe, van’t Veer, Cornelis, F. de Vos, Alex, Sirard, Jean-Claude, J. T. H. Roelofs, Joris, P. Scicluna, Brendon, van der Poll, Tom
Publicado 2021

The Adjuvant Activity of Alphavirus Replicons Is Enhanced by Incorporating the Microbial Molecule Flagellin into the Replicon

por Knudsen, Maria L., Johansson, Daniel X., Kostic, Linda, Nordström, Eva K. L., Tegerstedt, Karin, Pasetto, Anna, Applequist, Steven E., Ljungberg, Karl, Sirard, Jean-Claude, Liljeström, Peter
Publicado 2013

NADPH Oxidase Deficient Mice Develop Colitis and Bacteremia upon Infection with Normally Avirulent, TTSS-1- and TTSS-2-Deficient Salmonella Typhimurium

por Felmy, Boas, Songhet, Pascal, Slack, Emma Marie Caroline, Müller, Andreas J., Kremer, Marcus, Van Maele, Laurye, Cayet, Delphine, Heikenwalder, Mathias, Sirard, Jean-Claude, Hardt, Wolf-Dietrich
Publicado 2013

Local Treatment with Lactate Prevents Intestinal Inflammation in the TNBS-Induced Colitis Model

por Iraporda, Carolina, Romanin, David E., Bengoa, Ana A., Errea, Agustina J., Cayet, Delphine, Foligné, Benoit, Sirard, Jean-Claude, Garrote, Graciela L., Abraham, Analía G., Rumbo, Martín
Publicado 2016

Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection

por Beshara, Ranin, Sencio, Valentin, Soulard, Daphnée, Barthélémy, Adeline, Fontaine, Josette, Pinteau, Thibault, Deruyter, Lucie, Ismail, Mohamad Bachar, Paget, Christophe, Sirard, Jean-Claude, Trottein, François, Faveeuw, Christelle
Publicado 2018

The Use of Translational Modelling and Simulation to Develop Immunomodulatory Therapy as an Adjunct to Antibiotic Treatment in the Context of Pneumonia

por Michelet, Robin, Ursino, Moreno, Boulet, Sandrine, Franck, Sebastian, Casilag, Fiordiligie, Baldry, Mara, Rolff, Jens, van Dyk, Madelé, Wicha, Sebastian G., Sirard, Jean-Claude, Comets, Emmanuelle, Zohar, Sarah, Kloft, Charlotte
Publicado 2021

Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence

por Minhas, Vikrant, Domenech, Arnau, Synefiaridou, Dimitra, Straume, Daniel, Brendel, Max, Cebrero, Gonzalo, Liu, Xue, Costa, Charlotte, Baldry, Mara, Sirard, Jean-Claude, Perez, Camilo, Gisch, Nicolas, Hammerschmidt, Sven, Håvarstein, Leiv Sigve, Veening, Jan-Willem
Publicado 2023

The Microbiota Mediates Pathogen Clearance from the Gut Lumen after Non-Typhoidal Salmonella Diarrhea

por Endt, Kathrin, Stecher, Bärbel, Chaffron, Samuel, Slack, Emma, Tchitchek, Nicolas, Benecke, Arndt, Van Maele, Laurye, Sirard, Jean-Claude, Mueller, Andreas J., Heikenwalder, Mathias, Macpherson, Andrew J., Strugnell, Richard, von Mering, Christian, Hardt, Wolf-Dietrich
Publicado 2010