PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS

por McCall, Rebecca L., Sirianni, Rachael W.
Publicado 2013

EMBR-28. CNS DISTRIBUTIONAL KINETICS OF PANOBINOSTAT IN THE MOUSE

por Zhang, Wenqiu, Mohammad, Afroz, Sirianni, Rachael, Elmquist, William
Publicado 2021

Intravenously Administered, Retinoid Activating Nanoparticles Increase Lifespan and Reduce Neurodegeneration in the SOD1(G93A) Mouse Model of ALS

por Medina, David X., Chung, Eugene P., Teague, Collin D., Bowser, Robert, Sirianni, Rachael W.
Publicado 2020

Pathogen-inspired drug delivery to the central nervous system

por McCall, Rebecca L, Cacaccio, Joseph, Wrabel, Eileen, Schwartz, Mary E, Coleman, Timothy P, Sirianni, Rachael W
Publicado 2014

Poly(lactic-co-glycolic Acid) Nanoparticle Encapsulated 17β-Estradiol Improves Spatial Memory and Increases Uterine Stimulation in Middle-Aged Ovariectomized Rats

por Prakapenka, Alesia V., Quihuis, Alicia M., Carson, Catherine G., Patel, Shruti, Bimonte-Nelson, Heather A., Sirianni, Rachael W.
Publicado 2020

Targeting Small Molecule Delivery to the Brain and Spinal Cord via Intranasal Administration of Rabies Virus Glycoprotein (RVG29)-Modified PLGA Nanoparticles

por Chung, Eugene P., Cotter, Jennifer D., Prakapenka, Alesia V., Cook, Rebecca L., DiPerna, Danielle M., Sirianni, Rachael W.
Publicado 2020

Radiolabeling of Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles with Biotinylated F-18 Prosthetic Groups and Imaging of Their Delivery to the Brain with Positron Emission Tomog...

por Sirianni, Rachael W., Zheng, Ming-Qiang, Patel, Toral R., Shafbauer, Thomas, Zhou, Jiangbing, Saltzman, W. Mark, Carson, Richard E., Huang, Yiyun
Publicado 2014

pH driven precipitation of quisinostat onto PLA-PEG nanoparticles enables treatment of intracranial glioblastoma

por Householder, Kyle T., DiPerna, Danielle M., Chung, Eugene P., Luning, Anne Rosa, Nguyen, Duong T., Stabenfeldt, Sarah E., Mehta, Shwetal, Sirianni, Rachael W.
Publicado 2018

Intranasal 17β-Estradiol Modulates Spatial Learning and Memory in a Rat Model of Surgical Menopause

por Prakapenka, Alesia V., Peña, Veronica L., Strouse, Isabel, Northup-Smith, Steven, Schrier, Ally, Ahmed, Kinza, Bimonte-Nelson, Heather A., Sirianni, Rachael W.
Publicado 2020

DDEL-09. HIGH DOSE MTX110 (SOLUBLE PANOBINOSTAT) SAFELY ADMINISTERED INTO THE FOURTH VENTRICLE IN A NON-HUMAN PRIMATE MODEL

por Sirianni, Rachael W, Kharas, Natasha, Yu, Bangning, Janssen, Christopher F, Trimble, Amanda, Ballester, Leomar Y, Patel, Rajan, Mohammad, Afroz S, Elmquist, William F, Sandberg, David I
Publicado 2020

DDEL-10. A NANOPARTICLE PLATFORM FOR INTRATHECAL DELIVERY OF THE HISTONE DEACETYLASE INHIBITOR (HDACi) PANOBINOSTAT IN METASTATIC OR RECURRENT MEDULLOBLASTOMA

por Chaudhuri, Sauradip, Mohammad, Afroz S, Zhang, Wenqui, Baker, Cassandra, Broughton, Colton W, Fowler, Martha J, Stabenfeldt, Sarah E, Wechsler-Reya, Robert J, Sandberg, David I, Elmquist, William F, Sirianni, Rachael W
Publicado 2020

β-Cyclodextrin-poly (β-Amino Ester) Nanoparticles Are a Generalizable Strategy for High Loading and Sustained Release of HDAC Inhibitors

por Chaudhuri, Sauradip, Fowler, Martha J., Baker, Cassandra, Stopka, Sylwia A., Regan, Michael S., Sablatura, Lindsey, Broughton, Colton W., Knight, Brandon E., Stabenfeldt, Sarah E., Agar, Nathalie Y. R., Sirianni, Rachael W.
Publicado 2021