SU5416 plus hypoxia but not selective VEGFR2 inhibition with cabozantinib plus hypoxia induces pulmonary hypertension in rats: potential role of BMPR2 signaling

por Sitapara, Ravikumar, Sugarragchaa, Chuluunbaatar, Zisman, Lawrence S.
Publicado 2021

Phosphoproteomic analysis of lung tissue from patients with pulmonary arterial hypertension

por Sitapara, Ravikumar, Lam, TuKiet T., Gandjeva, Aneta, Tuder, Rubin M., Zisman, Lawrence S.
Publicado 2021

Pharmacology and Rationale for Seralutinib in the Treatment of Pulmonary Arterial Hypertension

por Pullamsetti, Soni Savai, Sitapara, Ravikumar, Osterhout, Robin, Weiss, Astrid, Carter, Laura L., Zisman, Lawrence S., Schermuly, Ralph Theo
Publicado 2023

GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function

por Sitapara, Ravikumar A., Gauthier, Alex G., Patel, Vivek S., Lin, Mosi, Zur, Michelle, Ashby, Charles R., Mantell, Lin L.
Publicado 2020

Correction to: GTS-21, an α7nAChR agonist, increases pulmonary bacterial clearance in mice by restoring hyperoxia-compromised macrophage function

por Sitapara, Ravikumar A., Gauthier, Alex G., Patel, Vivek S., Lin, Mosi, Zur, Michelle, Ashby, Charles R., Mantell, Lin L.
Publicado 2021

Expression of Concern to: The α7 nicotine acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function

por Sitapara, Ravikumar A., Antoine, Daniel J., Sharma, Lokesh, Patel, Vivek S., Ashby, Charles R., Gorasiya, Samir, Yang, Huan, Zur, Michelle, Mantell, Lin L.
Publicado 2020

Retraction Note: The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function

por Sitapara, Ravikumar A., Antoine, Daniel J., Sharma, Lokesh, Patel, Vivek S., Ashby, Charles R., Gorasiya, Samir, Yang, Huan, Zur, Michelle, Mantell, Lin L.
Publicado 2020

The Positive Allosteric Modulation of alpha7-Nicotinic Cholinergic Receptors by GAT107 Increases Bacterial Lung Clearance in Hyperoxic Mice by Decreasing Oxidative Stress in Macrop...

por Gauthier, Alex G., Wu, Jiaqi, Lin, Mosi, Sitapara, Ravikumar, Kulkarni, Abhijit, Thakur, Ganesh A., Schmidt, Edward E., Perron, Jeanette C., Ashby, Charles R., Mantell, Lin L.
Publicado 2021

Inhaled seralutinib exhibits potent efficacy in models of pulmonary arterial hypertension

por Galkin, Anna, Sitapara, Ravikumar, Clemons, Bryan, Garcia, Eduardo, Kennedy, Michael, Guimond, David, Carter, Laura L., Douthitt, Ashley, Osterhout, Robin, Gandjeva, Aneta, Slee, Deborah, Salter-Cid, Luisa, Tuder, Rubin M., Zisman, Lawrence S.
Publicado 2022

The α7 nicotinic acetylcholine receptor agonist, GTS-21, attenuates hyperoxia-induced acute inflammatory lung injury by alleviating the accumulation of HMGB1 in the airways and the...

por Sitapara, Ravikumar A., Gauthier, Alex G., Valdés-Ferrer, Sergio I., Lin, Mosi, Patel, Vivek, Wang, Mao, Martino, Ashley T., Perron, Jeanette C., Ashby, Charles R., Tracey, Kevin J., Pavlov, Valentin A., Mantell, Lin L.
Publicado 2020

Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury()()

por Entezari, Maria, Javdan, Mohammad, Antoine, Daniel J., Morrow, Dympna M.P., Sitapara, Ravikumar A., Patel, Vivek, Wang, Mao, Sharma, Lokesh, Gorasiya, Samir, Zur, Michelle, Wu, Wenjun, Li, JianHua, Yang, Huan, Ashby, Charles R., Thomas, Douglas, Wang, Haichao, Mantell, Lin L.
Publicado 2014