Universal protein misfolding intermediates can bypass the proteostasis network and remain soluble and less functional

por Nissley, Daniel A., Jiang, Yang, Trovato, Fabio, Sitarik, Ian, Narayan, Karthik B., To, Philip, Xia, Yingzi, Fried, Stephen D., O’Brien, Edward P.
Publicado 2022

How soluble misfolded proteins bypass chaperones at the molecular level

por Halder, Ritaban, Nissley, Daniel A., Sitarik, Ian, Jiang, Yang, Rao, Yiyun, Vu, Quyen V., Li, Mai Suan, Pritchard, Justin, O’Brien, Edward P.
Publicado 2023

Pulse labeling reveals the tail end of protein folding by proteome profiling

por Zhu, Mang, Kuechler, Erich R., Wong, Ryan W.K., Calabrese, Gaetano, Sitarik, Ian M., Rana, Viraj, Stoynov, Nikolay, O’Brien, Edward P., Gsponer, Jörg, Mayor, Thibault
Publicado 2022