Circulating Cell-Free Tumour DNA for Early Detection of Pancreatic Cancer

por Jaworski, Jedrzej J., Morgan, Robert D., Sivakumar, Shivan
Publicado 2020

The COVID-19 pandemic is associated with a change in origin of pathways to diagnosis of pancreatic cancer: a single-centre retrospective analysis

por Madge, Oliver, Bowen, Jordan, Sivakumar, Shivan, Bottomley, Matt
Publicado 2022

Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis

por Sivakumar, Shivan, de Santiago, Ines, Chlon, Leon, Markowetz, Florian
Publicado 2017

Biomarkers of response to PD-1 pathway blockade

por Li, Hanxiao, van der Merwe, P. Anton, Sivakumar, Shivan
Publicado 2022

HER2 Expression in Gastric Cancer: Rare, Heterogeneous and of No Prognostic Value – Conclusions from 924 Cases of Two Independent Series

por Grabsch, Heike, Sivakumar, Shivan, Gray, Sally, Gabbert, Helmut E., Müller, Wolfram
Publicado 2010

The COVID-19 Pandemic Is Associated with Reduced Survival after Pancreatic Ductal Adenocarcinoma Diagnosis: A Single-Centre Retrospective Analysis

por Madge, Oliver, Brodey, Alexandra, Bowen, Jordan, Nicholson, George, Sivakumar, Shivan, Bottomley, Matthew J.
Publicado 2022

Advances in Immunotherapeutics in Pancreatic Ductal Adenocarcinoma

por Chouari, Tarak, La Costa, Francesca Soraya, Merali, Nabeel, Jessel, Maria-Danae, Sivakumar, Shivan, Annels, Nicola, Frampton, Adam E.
Publicado 2023

Immunophenotypes of pancreatic ductal adenocarcinoma: Meta‐analysis of transcriptional subtypes

por de Santiago, Ines, Yau, Christopher, Heij, Lara, Middleton, Mark R., Markowetz, Florian, Grabsch, Heike I., Dustin, Michael L., Sivakumar, Shivan
Publicado 2019

Temporality of body mass index, blood tests, comorbidities and medication use as early markers for pancreatic ductal adenocarcinoma (PDAC): a nested case–control study

por Tan, Pui San, Garriga, Cesar, Clift, Ashley, Liao, Weiqi, Patone, Martina, Coupland, Carol, Bashford-Rogers, Rachael, Sivakumar, Shivan, Hippisley-Cox, Julia
Publicado 2023

Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (Ther...

por Spiers, Laura, Gray, Michael, Lyon, Paul, Sivakumar, Shivan, Bekkali, Noor, Scott, Shaun, Collins, Linda, Carlisle, Robert, Wu, Feng, Middleton, Mark, Coussios, Constantin
Publicado 2023

ToxNav germline genetic testing and PROMinet digital mobile application toxicity monitoring: Results of a prospective single‐center clinical utility study—PRECISE study

por Lee, Lennard Y. W., Starkey, Thomas, Sivakumar, Shivan, Fotheringham, Susan, Mozolowski, Guy, Shearwood, Vanessa, Palles, Claire, Camilleri, Philip, Church, David, Kerr, Rachel, Kerr, David
Publicado 2019

Pseudotime dynamics of T cells in pancreatic ductal adenocarcinoma inform distinct functional states within the regulatory and cytotoxic T cells

por Jainarayanan, Ashwin, Mouroug-Anand, Nithishwer, Arbe-Barnes, Edward H., Bush, Adam J., Bashford-Rogers, Rachael, Frampton, Adam, Heij, Lara, Middleton, Mark, Dustin, Michael L., Abu-Shah, Enas, Sivakumar, Shivan
Publicado 2023

Expression of Checkpoint Molecules in the Tumor Microenvironment of Intrahepatic Cholangiocarcinoma: Implications for Immune Checkpoint Blockade Therapy

por Heij, Lara, Bednarsch, Jan, Tan, Xiuxiang, Rosin, Mika, Appinger, Simone, Reichel, Konrad, Pecina, Dana, Doukas, Michail, van Dam, Ronald M., Garcia Vallejo, Juan, Ulmer, Florian, Lang, Sven, Luedde, Tom, Rocha, Flavio G., Sivakumar, Shivan, Neumann, Ulf Peter
Publicado 2023

Evaluation of pre-analytical factors affecting plasma DNA analysis

por Markus, Havell, Contente-Cuomo, Tania, Farooq, Maria, Liang, Winnie S., Borad, Mitesh J., Sivakumar, Shivan, Gollins, Simon, Tran, Nhan L., Dhruv, Harshil D., Berens, Michael E., Bryce, Alan, Sekulic, Aleksandar, Ribas, Antoni, Trent, Jeffrey M., LoRusso, Patricia M., Murtaza, Muhammed
Publicado 2018

Activated Regulatory T-Cells, Dysfunctional and Senescent T-Cells Hinder the Immunity in Pancreatic Cancer

por Sivakumar, Shivan, Abu-Shah, Enas, Ahern, David J., Arbe-Barnes, Edward H., Jainarayanan, Ashwin K., Mangal, Nagina, Reddy, Srikanth, Rendek, Aniko, Easton, Alistair, Kurz, Elke, Silva, Michael, Soonawalla, Zahir, Heij, Lara R., Bashford-Rogers, Rachael, Middleton, Mark R., Dustin, Michael L.
Publicado 2021

The Presence of Small Nerve Fibers in the Tumor Microenvironment as Predictive Biomarker of Oncological Outcome Following Partial Hepatectomy for Intrahepatic Cholangiocarcinoma

por Bednarsch, Jan, Tan, Xiuxiang, Czigany, Zoltan, Liu, Dong, Lang, Sven Arke, Sivakumar, Shivan, Kather, Jakob Nikolas, Appinger, Simone, Rosin, Mika, Boroojerdi, Shiva, Dahl, Edgar, Gaisa, Nadine Therese, den Dulk, Marcel, Coolsen, Mariëlle, Ulmer, Tom Florian, Neumann, Ulf Peter, Heij, Lara Rosaline
Publicado 2021

Cell-free DNA TAPS provides multimodal information for early cancer detection

por Siejka-Zielińska, Paulina, Cheng, Jingfei, Jackson, Felix, Liu, Yibin, Soonawalla, Zahir, Reddy, Srikanth, Silva, Michael, Puta, Luminita, McCain, Misti Vanette, Culver, Emma L., Bekkali, Noor, Schuster-Böckler, Benjamin, Palamara, Pier Francesco, Mann, Derek, Reeves, Helen, Barnes, Eleanor, Sivakumar, Shivan, Song, Chun-Xiao
Publicado 2021

Nerve fibers in the tumor microenvironment in neurotropic cancer—pancreatic cancer and cholangiocarcinoma

por Tan, Xiuxiang, Sivakumar, Shivan, Bednarsch, Jan, Wiltberger, Georg, Kather, Jakob Nikolas, Niehues, Jan, de Vos-Geelen, Judith, Valkenburg-van Iersel, Liselot, Kintsler, Svetlana, Roeth, Anjali, Hao, Guangshan, Lang, Sven, Coolsen, Mariëlle E., den Dulk, Marcel, Aberle, Merel R., Koolen, Jarne, Gaisa, Nadine T., Olde Damink, Steven W. M., Neumann, Ulf P., Heij, Lara R.
Publicado 2020

Nerve Fibers in the Tumor Microenvironment Are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer

por Heij, Lara R., Tan, Xiuxiang, Kather, Jakob N., Niehues, Jan M., Sivakumar, Shivan, Heussen, Nicole, van der Kroft, Gregory, Damink, Steven W. M. Olde, Lang, Sven, Aberle, Merel R., Luedde, Tom, Gaisa, Nadine T., Bednarsch, Jan, Liu, Drolaiz H. W., Cleutjens, Jack P. M., Modest, Dominik P., Neumann, Ulf P., Wiltberger, Georg J.
Publicado 2021

A bile-based microRNA signature for differentiating malignant from benign pancreaticobiliary disease

por Mato Prado, Mireia, Puik, Jisce R., Castellano, Leandro, López-Jiménez, Elena, Liu, Daniel S. K., Meijer, Laura L., Le Large, Tessa Y. S., Rees, Eleanor, Funel, Niccola, Sivakumar, Shivan, Pereira, Stephen P., Kazemier, Geert, Zonderhuis, Babs M., Erdmann, Joris I., Swijnenburg, Rutger-Jan, Frilling, Andrea, Jiao, Long R., Stebbing, Justin, Giovannetti, Elisa, Krell, Jonathan, Frampton, Adam E.
Publicado 2023