The expanding role of the ER translocon in membrane protein folding

por Skach, William R.
Publicado 2007

Mechanisms of CFTR Folding at the Endoplasmic Reticulum

por Kim, Soo Jung, Skach, William R.
Publicado 2012

Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum–associated degradation

por Matsumura, Yoshihiro, David, Larry L., Skach, William R.
Publicado 2011

A small molecule high throughput screening platform to profile conformational properties of nascent, ribosome-bound proteins

por Shishido, Hideki, Yoon, Jae Seok, Skach, William R.
Publicado 2022

CFTR trafficking mutations disrupt cotranslational protein folding by targeting biosynthetic intermediates

por Shishido, Hideki, Yoon, Jae Seok, Yang, Zhongying, Skach, William R.
Publicado 2020

Cotranslational Folding Inhibits Translocation from Within the Ribosome–Sec61 Translocon Complex

por Conti, Brian J., Elferich, Johannes, Yang, Zhongying, Shinde, Ujwal, Skach, William R.
Publicado 2014

N-terminal transmembrane domain of SUR1 controls gating of Kir6.2 by modulating channel sensitivity to PIP(2)

por Pratt, Emily B., Tewson, Paul, Bruederle, Cathrin E., Skach, William R., Shyng, Show-Ling
Publicado 2011

A role for the ribosome-associated complex in activation of the IRE1 branch of UPR

por Wu, I-Hui, Yoon, Jae Seok, Yang, Qian, Liu, Yi, Skach, William, Thomas, Philip
Publicado 2021

Real-Time Fluorescence Detection of ERAD Substrate Retrotranslocation in a Mammalian In Vitro System

por Wahlman, Judit, DeMartino, George N., Skach, William R., Bulleid, Neil J., Brodsky, Jeffrey L., Johnson, Arthur E.
Publicado 2007

Role of Hsp90 in Biogenesis of the β-Cell ATP-sensitive Potassium Channel Complex

por Yan, Fei-Fei, Pratt, Emily B., Chen, Pei-Chun, Wang, Fang, Skach, William R., David, Larry L., Shyng, Show-Ling
Publicado 2010

Cystic Fibrosis Transmembrane Conductance Regulator–associated ATP Release Is Controlled by a Chloride Sensor

por Jiang, Qinshi, Mak, Daniel, Devidas, Sreenivas, Schwiebert, Erik M., Bragin, Alvina, Zhang, Yulong, Skach, William R., Guggino, William B., Foskett, J. Kevin, Engelhardt, John F.
Publicado 1998

Towards next generation therapies for cystic fibrosis: Folding, function and pharmacology of CFTR()

por Bose, Samuel J., Krainer, Georg, Ng, Demi R.S., Schenkel, Mathias, Shishido, Hideki, Yoon, Jae Seok, Haggie, Peter M., Schlierf, Michael, Sheppard, David N., Skach, William R.
Publicado 2020

Engineered transfer RNAs for suppression of premature termination codons

por Lueck, John D., Yoon, Jae Seok, Perales-Puchalt, Alfredo, Mackey, Adam L., Infield, Daniel T., Behlke, Mark A., Pope, Marshall R., Weiner, David B., Skach, William R., McCray, Paul B., Ahern, Christopher A.
Publicado 2019

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

por Veit, Gudio, Avramescu, Radu G., Chiang, Annette N., Houck, Scott A., Cai, Zhiwei, Peters, Kathryn W., Hong, Jeong S., Pollard, Harvey B., Guggino, William B., Balch, William E., Skach, William R., Cutting, Garry R., Frizzell, Raymond A., Sheppard, David N., Cyr, Douglas M., Sorscher, Eric J., Brodsky, Jeffrey L., Lukacs, Gergely L.
Publicado 2016