Mechanism of action of the third generation benzopyrans and evaluation of their broad anti-cancer activity in vitro and in vivo

por Stevenson, Alexander J., Ager, Eleanor I., Proctor, Martina A., Škalamera, Dubravka, Heaton, Andrew, Brown, David, Gabrielli, Brian G.
Publicado 2018

Generation of a Genome Scale Lentiviral Vector Library for EF1α Promoter-Driven Expression of Human ORFs and Identification of Human Genes Affecting Viral Titer

por Škalamera, Dubravka, Dahmer, Mareike, Purdon, Amy S., Wilson, Benjamin M., Ranall, Max V., Blumenthal, Antje, Gabrielli, Brian, Gonda, Thomas J.
Publicado 2012

Dysregulated G2 phase checkpoint recovery pathway reduces DNA repair efficiency and increases chromosomal instability in a wide range of tumours

por Fernando, Madushan, Duijf, Pascal H. G., Proctor, Martina, Stevenson, Alexander J., Ehmann, Anna, Vora, Shivam, Skalamera, Dubravka, Adams, Mark, Gabrielli, Brian
Publicado 2021

A High-Throughput Platform for Lentiviral Overexpression Screening of the Human ORFeome

por Škalamera, Dubravka, Ranall, Max V., Wilson, Benjamin M., Leo, Paul, Purdon, Amy S., Hyde, Carolyn, Nourbakhsh, Ehsan, Grimmond, Sean M., Barry, Simon C., Gabrielli, Brian, Gonda, Thomas J.
Publicado 2011

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine

por Oo, Zay Yar, Proctor, Martina, Stevenson, Alexander J., Nazareth, Deborah, Fernando, Madushan, Daignault, Sheena M., Lanagan, Catherine, Walpole, Sebastian, Bonazzi, Vanessa, Škalamera, Dubravka, Snell, Cameron, Haass, Nikolas K., Larsen, Jill E., Gabrielli, Brian
Publicado 2019

Multiple interaction nodes define the postreplication repair response to UV‐induced DNA damage that is defective in melanomas and correlated with UV signature mutation load

por Pavey, Sandra, Pinder, Alex, Fernando, Winnie, D’Arcy, Nicholas, Matigian, Nicholas, Skalamera, Dubravka, Lê Cao, Kim‐Anh, Loo‐Oey, Dorothy, Hill, Michelle M., Stark, Mitchell, Kimlin, Michael, Burgess, Andrew, Cloonan, Nicole, Sturm, Richard A., Gabrielli, Brian
Publicado 2019

Genome-wide gain-of-function screen for genes that induce epithelial-to-mesenchymal transition in breast cancer

por Škalamera, Dubravka, Dahmer-Heath, Mareike, Stevenson, Alexander J., Pinto, Cletus, Shah, Esha T., Daignault, Sheena M., Said, Nur Akmarina B.M., Davis, Melissa, Haass, Nikolas K., Williams, Elizabeth D., Hollier, Brett G., Thompson, Erik W., Gabrielli, Brian, Gonda, Thomas J.
Publicado 2016