A highly sensitive prenylation assay reveals in vivo effects of bisphosphonate drug on the Rab prenylome of macrophages outside the skeleton

por Ali, Naveid, Jurczyluk, Julie, Shay, Gemma, Tnimov, Zakir, Alexandrov, Kirill, Munoz, Marcia A, Skinner, Oliver P, Pavlos, Nathan J, Rogers, Michael J
Publicado 2015

Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages

por Munoz, Marcia A, Fletcher, Emma K, Skinner, Oliver P, Jurczyluk, Julie, Kristianto, Esther, Hodson, Mark P, Sun, Shuting, Ebetino, Frank H, Croucher, David R, Hansbro, Philip M, Center, Jacqueline R, Rogers, Michael J
Publicado 2021

Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases

por Jurczyluk, Julie, Munoz, Marcia A, Skinner, Oliver P, Chai, Ryan C, Ali, Naveid, Palendira, Umaimainthan, Quinn, Julian MW, Preston, Alexandra, Tangye, Stuart G, Brown, Andrew J, Argent, Elizabeth, Ziegler, John B, Mehr, Sam, Rogers, Michael J
Publicado 2016

Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency

por Munoz, Marcia A., Skinner, Oliver P., Masle-Farquhar, Etienne, Jurczyluk, Julie, Xiao, Ya, Fletcher, Emma K., Kristianto, Esther, Hodson, Mark P., O’Donoghue, Seán I., Kaur, Sandeep, Brink, Robert, Zahra, David G., Deenick, Elissa K., Perry, Kristen A., Robertson, Avril A.B., Mehr, Sam, Hissaria, Pravin, Mulders-Manders, Catharina M., Simon, Anna, Rogers, Michael J.
Publicado 2022

Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites

por Lansink, Lianne I. M., Skinner, Oliver P., Engel, Jessica A., Lee, Hyun Jae, Soon, Megan S. F., Williams, Cameron G., SheelaNair, Arya, Pernold, Clara P. S., Laohamonthonkul, Pawat, Akter, Jasmin, Stoll, Thomas, Hill, Michelle M., Talman, Arthur M., Russell, Andrew, Lawniczak, Mara, Jia, Xiaoxiao, Chua, Brendon, Anderson, Dovile, Creek, Darren J., Davenport, Miles P., Khoury, David S., Haque, Ashraful
Publicado 2023