20.4 MODELING THE CONTRIBUTION OF COMMON VARIANTS TO SCHIZOPHRENIA RISK

por Hoffman, Gabriel, Hartley, Brigham, Ruderfer, Douglas, Rapoport, Judith, Sklar, Pamela, Brennand, Kristen
Publicado 2018

Accurately Assessing the Risk of Schizophrenia Conferred by Rare Copy-Number Variation Affecting Genes with Brain Function

por Raychaudhuri, Soumya, Korn, Joshua M., McCarroll, Steven A., Altshuler, David, Sklar, Pamela, Purcell, Shaun, Daly, Mark J.
Publicado 2010

A molecular approach to treating cognition in schizophrenia by calcium channel blockade: An open-label pilot study of the calcium-channel antagonist isradipine

por Burdick, Katherine E., Perez-Rodriguez, Mercedes, Birnbaum, Rebecca, Shanahan, Megan, Larsen, Emmett, Harper, Cierra, Poskus, Jessica, Sklar, Pamela
Publicado 2020

Ankyrin-G Regulates Neurogenesis and Wnt Signaling by Altering the Subcellular Localization of β-catenin

por Durak, Omer, de Anda, Froylan Calderon, Singh, Karun K., Leussis, Melanie P., Petryshen, Tracey L., Sklar, Pamela, Tsai, Li-Huei
Publicado 2014

Evaluating Historical Candidate Genes for Schizophrenia

por Farrell, Martilias, Werge, Thomas, Sklar, Pamela, Owen, Michael J., Ophoff, Roel, O’Donovan, Michael, Corvin, Aiden, Cichon, Sven, Sullivan, Patrick F
Publicado 2015

Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains

por Hoffman, Gabriel E., Hartley, Brigham J., Flaherty, Erin, Ladran, Ian, Gochman, Peter, Ruderfer, Douglas M., Stahl, Eli A., Rapoport, Judith, Sklar, Pamela, Brennand, Kristen J.
Publicado 2017

Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia

por Breen, Michael S., Dobbyn, Amanda, Li, Qin, Roussos, Panos, Hoffman, Gabriel E., Stahl, Eli, Chess, Andrew, Sklar, Pamela, Li, Jin Billy, Devlin, Bernie, Buxbaum, Joseph D.
Publicado 2019

Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions

por Raychaudhuri, Soumya, Plenge, Robert M., Rossin, Elizabeth J., Ng, Aylwin C. Y., Purcell, Shaun M., Sklar, Pamela, Scolnick, Edward M., Xavier, Ramnik J., Altshuler, David, Daly, Mark J.
Publicado 2009

Evidence for genetic association of RORB with bipolar disorder

por McGrath, Casey L, Glatt, Stephen J, Sklar, Pamela, Le-Niculescu, Helen, Kuczenski, Ronald, Doyle, Alysa E, Biederman, Joseph, Mick, Eric, Faraone, Stephen V, Niculescu, Alexander B, Tsuang, Ming T
Publicado 2009

Expression-based drug screening of neural progenitor cells from individuals with schizophrenia

por Readhead, Benjamin, Hartley, Brigham J., Eastwood, Brian J., Collier, David A., Evans, David, Farias, Richard, He, Ching, Hoffman, Gabriel, Sklar, Pamela, Dudley, Joel T., Schadt, Eric E., Savić, Radoslav, Brennand, Kristen J.
Publicado 2018

Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia

por Readhead, Benjamin, Hartley, Brigham J., Eastwood, Brian J., Collier, David A., Evans, David, Farias, Richard, He, Ching, Hoffman, Gabriel, Sklar, Pamela, Dudley, Joel T., Schadt, Eric E., Savić, Radoslav, Brennand, Kristen J.
Publicado 2018

De novo CNVs in bipolar affective disorder and schizophrenia

por Georgieva, Lyudmila, Rees, Elliott, Moran, Jennifer L., Chambert, Kimberly D., Milanova, Vihra, Craddock, Nicholas, Purcell, Shaun, Sklar, Pamela, McCarroll, Steven, Holmans, Peter, O'Donovan, Michael C., Owen, Michael J., Kirov, George
Publicado 2014

Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

por Genovese, Giulio, Fromer, Menachem, Stahl, Eli A., Ruderfer, Douglas M., Chambert, Kimberly, Landén, Mikael, Moran, Jennifer L., Purcell, Shaun M., Sklar, Pamela, Sullivan, Patrick F., Hultman, Christina M., McCarroll, Steven A.
Publicado 2016

Examining the role of common and rare mitochondrial variants in schizophrenia

por Gonçalves, Vanessa F, Giamberardino, Stephanie N., Crowley, James J., Vawter, Marquis P., Saxena, Richa, Bulik, Cynthia M., Yilmaz, Zeynep, Hultman, Christina M., Sklar, Pamela, Kennedy, James L., Sullivan, Patrick F., Knight, Jo
Publicado 2018

Cis-Acting Regulation of Brain-Specific ANK3 Gene Expression by a Genetic Variant Associated with Bipolar Disorder

por Rueckert, Erroll H., Barker, Douglas, Ruderfer, Douglas, Bergen, Sarah E., O’Dushlaine, Colm, Luce, Catherine J., Sheridan, Steven D., Theriault, Kraig M., Chambert, Kimberly, Moran, Jennifer, Purcell, Shaun, Madison, Jon M., Haggarty, Stephen J., Sklar, Pamela
Publicado 2012

Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility

por Raj, Towfique, Li, Yang I., Wong, Garrett, Humphrey, Jack, Wang, Minghui, Ramdhani, Satesh, Wang, Ying-Chih, Ng, Bernard, Gupta, Ishaan, Haroutunian, Vahram, Schadt, Eric E., Young-Pearse, Tracy, Mostafavi, Sara, Zhang, Bin, Sklar, Pamela, Bennett, David A., De Jager, Philip L.
Publicado 2018

Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

por Andreassen, Ole A., Thompson, Wesley K., Schork, Andrew J., Ripke, Stephan, Mattingsdal, Morten, Kelsoe, John R., Kendler, Kenneth S., O'Donovan, Michael C., Rujescu, Dan, Werge, Thomas, Sklar, Pamela, Roddey, J. Cooper, Chen, Chi-Hua, McEvoy, Linda, Desikan, Rahul S., Djurovic, Srdjan, Dale, Anders M.
Publicado 2013

Most genetic risk for autism resides with common variation

por Gaugler, Trent, Klei, Lambertus, Sanders, Stephan J., Bodea, Corneliu A., Goldberg, Arthur P., Lee, Ann B., Mahajan, Milind, Manaa, Dina, Pawitan, Yudi, Reichert, Jennifer, Ripke, Stephan, Sandin, Sven, Sklar, Pamela, Svantesson, Oscar, Reichenberg, Abraham, Hultman, Christina M., Devlin, Bernie, Roeder, Kathryn, Buxbaum, Joseph D.
Publicado 2014

Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate

por Andreassen, Ole A., Thompson, Wesley K., Schork, Andrew J., Ripke, Stephan, Mattingsdal, Morten, Kelsoe, John R., Kendler, Kenneth S., O'Donovan, Michael C., Rujescu, Dan, Werge, Thomas, Sklar, Pamela, Roddey, J. Cooper, Chen, Chi-Hua, McEvoy, Linda, Desikan, Rahul S., Djurovic, Srdjan, Dale, Anders M.
Publicado 2015

Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records

por Chen, Chia-Yen, Lee, Phil H., Castro, Victor M., Minnier, Jessica, Charney, Alexander W., Stahl, Eli A., Ruderfer, Douglas M., Murphy, Shawn N., Gainer, Vivian, Cai, Tianxi, Jones, Ian, Pato, Carlos N., Pato, Michele T., Landén, Mikael, Sklar, Pamela, Perlis, Roy H., Smoller, Jordan W.
Publicado 2018