A New Take on V(D)J Recombination: Transcription Driven Nuclear and Chromatin Reorganization in Rag-Mediated Cleavage

por Chaumeil, Julie, Skok, Jane A.
Publicado 2013

The RAG2 C-terminus and ATM protect genome integrity by controlling antigen receptor gene cleavage

por Chaumeil, Julie, Micsinai, Mariann, Ntziachristos, Panagiotis, Roth, David B., Aifantis, Iannis, Kluger, Yuval, Deriano, Ludovic, Skok, Jane A.
Publicado 2013

CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci

por Fu, Yi, Rocha, Pedro P., Luo, Vincent M., Raviram, Ramya, Deng, Yan, Mazzoni, Esteban O., Skok, Jane A.
Publicado 2016

Silencing and Nuclear Repositioning of the λ5 Gene Locus at the Pre-B Cell Stage Requires Aiolos and OBF-1

por Karnowski, Alexander, Cao, Chun, Matthias, Gabriele, Carotta, Sebastian, Corcoran, Lynn M., Martensson, Inga-Lill, Skok, Jane A., Matthias, Patrick
Publicado 2008

Identification of multi-loci hubs from 4C-seq demonstrates the functional importance of simultaneous interactions

por Jiang, Tingting, Raviram, Ramya, Snetkova, Valentina, Rocha, Pedro P., Proudhon, Charlotte, Badri, Sana, Bonneau, Richard, Skok, Jane A., Kluger, Yuval
Publicado 2016

Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice

por Cantor, David J., King, Bryan, Blumenberg, Lili, DiMauro, Teresa, Aifantis, Iannis, Koralov, Sergei B., Skok, Jane A., David, Gregory
Publicado 2019

MethNet: a robust approach to identify regulatory hubs and their distal targets in cancer

por Sakellaropoulos, Theodore, Do, Catherine, Jiang, Guimei, Cova, Giulia, Meyn, Peter, Dimartino, Dacia, Ramaswami, Sitharam, Heguy, Adriana, Tsirigos, Aristotelis, Skok, Jane A
Publicado 2023

The RAG2 C-terminus suppresses genomic instability and lymphomagenesis

por Deriano, Ludovic, Chaumeil, Julie, Coussens, Marc, Multani, Asha, Chou, YiFan, Alekseyenko, Alexander V., Chang, Sandy, Skok, Jane A., Roth, David B.
Publicado 2011

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development

por Issuree, Priya D., Day, Kenneth, Au, Christy, Raviram, Ramya, Zappile, Paul, Skok, Jane A., Xue, Hai-Hui, Myers, Richard M., Littman, Dan R.
Publicado 2018

Analysis of 3D genomic interactions identifies candidate host genes that transposable elements potentially regulate

por Raviram, Ramya, Rocha, Pedro P., Luo, Vincent M., Swanzey, Emily, Miraldi, Emily R., Chuong, Edward B., Feschotte, Cédric, Bonneau, Richard, Skok, Jane A.
Publicado 2018

CRISPR and biochemical screens identify MAZ as a cofactor in CTCF-mediated insulation at Hox clusters

por Ortabozkoyun, Havva, Huang, Pin-Yao, Cho, Hyunwoo, Narendra, Varun, LeRoy, Gary, Gonzalez-Buendia, Edgar, Skok, Jane A., Tsirigos, Aristotelis, Mazzoni, Esteban O., Reinberg, Danny
Publicado 2022

4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments

por Raviram, Ramya, Rocha, Pedro P., Müller, Christian L., Miraldi, Emily R., Badri, Sana, Fu, Yi, Swanzey, Emily, Proudhon, Charlotte, Snetkova, Valentina, Bonneau, Richard, Skok, Jane A.
Publicado 2016

NSD2 overexpression drives clustered chromatin and transcriptional changes in a subset of insulated domains

por Lhoumaud, Priscillia, Badri, Sana, Rodriguez-Hernaez, Javier, Sakellaropoulos, Theodore, Sethia, Gunjan, Kloetgen, Andreas, Cornwell, MacIntosh, Bhattacharyya, Sourya, Ay, Ferhat, Bonneau, Richard, Tsirigos, Aristotelis, Skok, Jane A.
Publicado 2019

Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation

por Nishana, Mayilaadumveettil, Ha, Caryn, Rodriguez-Hernaez, Javier, Ranjbaran, Ali, Chio, Erica, Nora, Elphege P., Badri, Sana B., Kloetgen, Andreas, Bruneau, Benoit G., Tsirigos, Aristotelis, Skok, Jane A.
Publicado 2020

Author Correction: Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation

por Nishana, Mayilaadumveettil, Ha, Caryn, Rodriguez-Hernaez, Javier, Ranjbaran, Ali, Chio, Erica, Nora, Elphege P., Badri, Sana B., Kloetgen, Andreas, Bruneau, Benoit G., Tsirigos, Aristotelis, Skok, Jane A.
Publicado 2020

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage

por Wong, Jason B., Hewitt, Susannah L., Heltemes-Harris, Lynn M., Mandal, Malay, Johnson, Kristen, Rajewsky, Klaus, Koralov, Sergei B., Clark, Marcus R., Farrar, Michael A., Skok, Jane A.
Publicado 2019

The Conserved ATM Kinase RAG2-S365 Phosphorylation Site Limits Cleavage Events in Individual Cells Independent of Any Repair Defect

por Hewitt, Susannah L., Wong, Jason B., Lee, Ji-Hoon, Nishana, Mayilaadumveettil, Chen, Hongxi, Coussens, Marc, Arnal, Suzzette M., Blumenberg, Lili M., Roth, David B., Paull, Tanya T., Skok, Jane A.
Publicado 2017

Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination

por Thomas-Claudepierre, Anne-Sophie, Robert, Isabelle, Rocha, Pedro P., Raviram, Ramya, Schiavo, Ebe, Heyer, Vincent, Bonneau, Richard, Luo, Vincent M., Reddy, Janardan K., Borggrefe, Tilman, Skok, Jane A., Reina-San-Martin, Bernardo
Publicado 2016

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination

por Rocha, Pedro P., Raviram, Ramya, Fu, Yi, Kim, JungHyun, Luo, Vincent M., Aljoufi, Arafat, Swanzey, Emily, Pasquarella, Alessandra, Balestrini, Alessia, Miraldi, Emily R., Bonneau, Richard, Petrini, John, Schotta, Gunnar, Skok, Jane A.
Publicado 2016

Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms

por Mullenders, Jasper, Aranda-Orgilles, Beatriz, Lhoumaud, Priscillia, Keller, Matthew, Pae, Juhee, Wang, Kun, Kayembe, Clarisse, Rocha, Pedro P., Raviram, Ramya, Gong, Yixiao, Premsrirut, Prem K., Tsirigos, Aristotelis, Bonneau, Richard, Skok, Jane A., Cimmino, Luisa, Hoehn, Daniela, Aifantis, Iannis
Publicado 2015