Generation, expansion, and drug treatment of hematopoietic progenitor cells derived from human iPSCs

por Dannenmann, Benjamin, Skokowa, Julia
Publicado 2022

P458: HIPSC DISEASE MODELING TO STUDY LEUKEMIA DEVELOPMENT IN HAX1 VS ELANE ASSOCIATED CONGENITAL NEUTROPENIA

por Dannenmann, Benjamin, Klimiankou, Maksim, Zeidler, Cornelia, Welte, Karl, Skokowa, Julia
Publicado 2023

PB1703: MODELING T-CELL DEVELOPMENT AND T-ALL INITIATION

por Dick, Advaita M, Tsingos, Erika, Aghaallaei, Narges, Skokowa, Julia, Bajoghli, Baubak
Publicado 2023

A zebrafish model for HAX1-associated congenital neutropenia

por Doll, Larissa, Aghaallaei, Narges, Dick, Advaita M., Welte, Karl, Skokowa, Julia, Bajoghli, Baubak
Publicado 2020

P750: A ZEBRAFISH MODEL FOR JAGN1-ASSOCIATED SEVERE CONGENITAL NEUTROPENIA

por Doll, Larissa, Aghaallaei, Narges, Lengerke, Claudia, Zeidler, Cornelia, Welte, Karl, Skokowa, Julia, Bajoghli, Baubak
Publicado 2023

Regenerative medicine meets translational oncology: Modeling leukemic bone marrow niche

por Borbaran-Bravo, Natalia, Arreba-Tutusaus, Patricia, Ritter, Malte U., Nasri, Masoud, Klimiankou, Maksim, Skokowa, Julia
Publicado 2022

Correction: NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells

por Xu, Yun, Nasri, Masoud, Dannenmann, Benjamin, Mir, Perihan, Zahabi, Azadeh, Welte, Karl, Morishima, Tatsuya, Skokowa, Julia
Publicado 2023

NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells

por Xu, Yun, Nasri, Masoud, Dannenmann, Benjamin, Mir, Perihan, Zahabi, Azadeh, Welte, Karl, Morishima, Tatsuya, Skokowa, Julia
Publicado 2021

P780: G-CSF THERAPY IN EUROPEAN PATIENTS WITH SHWACHMAN-DIAMOND SYNDROME

por Mellor-Heineke, Sabine, Skokowa, Julia, Gerschmann, Natali, Deordieva, Ekatharina, Schsherbina, Anna, Tesakov, Ivan, Welte, Karl, Zeidler, Cornelia
Publicado 2023

Ultra-Sensitive CSF3R Deep Sequencing in Patients With Severe Congenital Neutropenia

por Klimiankou, Maksim, Uenalan, Murat, Kandabarau, Siarhei, Nustede, Rainer, Steiert, Ingeborg, Mellor-Heineke, Sabine, Zeidler, Cornelia, Skokowa, Julia, Welte, Karl
Publicado 2019

Cooperating, congenital neutropenia–associated Csf3r and Runx1 mutations activate pro-inflammatory signaling and inhibit myeloid differentiation of mouse HSPCs

por Ritter, Malte, Klimiankou, Maksim, Klimenkova, Olga, Schambach, Axel, Hoffmann, Dirk, Schmidt, Amy, Kanz, Lothar, Link, Daniel C., Welte, Karl, Skokowa, Julia
Publicado 2020

P751: UNRAVELING THE DIFFERENT PATHOMECHANISMS OF CONGENITAL AND CYCLIC NEUTROPENIAS: CYCLIC EXPRESSION OF HEMATOPOIETIC STEM-CELL-SPECIFIC TRANSCRIPTION FACTORS IN CYCLIC NEUTROPE...

por Alexander Zeidler, Karl, Borbaran-Bravo, Natalia, Ritter, Malte, Nasri, Masoud, Klimiankou, Maksim, Kandabarau, Sergey, König, Josef, Zeidler, Cornelia, Skokowa, Julia, Welte, Karl
Publicado 2023

Neutrophils: Between Host Defence, Immune Modulation, and Tissue Injury

por Kruger, Philipp, Saffarzadeh, Mona, Weber, Alexander N. R., Rieber, Nikolaus, Radsak, Markus, von Bernuth, Horst, Benarafa, Charaf, Roos, Dirk, Skokowa, Julia, Hartl, Dominik
Publicado 2015

S178: A NEW HEREDITARY SYNDROME WITH SEVERE NEUTROPENIA AND NEUROLOGICAL INVOLVEMENT CAUSED BY THE AUTOSOMAL RECESSIVE COPZ1 MUTATION

por Borbaran Bravo, Natalia, Doll, Larissa, Deordieva, Ekaterina, Bräuning, Sandro, Dannenmann, Benjamin, Elgamacy, Mohammad, Zakharova, Viktoria, Lengerke, Claudia, Zeidler, Cornelia, Welte, Karl, Shcherbina, Anna, Skokowa, Julia, Klimiankou, Maksim
Publicado 2023

Design of novel granulopoietic proteins by topological rescaffolding

por Hernandez Alvarez, Birte, Skokowa, Julia, Coles, Murray, Mir, Perihan, Nasri, Masoud, Maksymenko, Kateryna, Weidmann, Laura, Rogers, Katherine W., Welte, Karl, Lupas, Andrei N., Müller, Patrick, ElGamacy, Mohammad
Publicado 2020

P1357: MILESTONE (MODIFYING ELANE GOLDBERG–HOGNES BOX TO INHIBIT EXPRESSION), A UNIVERSAL, SAFE AND EFFECTIVE CRISPR/CAS9N-MEDIATED GENOME EDITING STRATEGY FOR ELANE RELATED SEVERE...

por Nasri, Masoud, Ulrich Ritter, Malte, Mir, Perihan, Dannenmann, Benjamin, Monika Kaufmann, Masako, Xu, Yun, Borbaran-Bravo, Natalia, Klimiankou, Maksim, Lengerke, Claudia, Zeidler, Cornelia, Cathomen, Toni, Welte, Karl, Skokowa, Julia
Publicado 2023

The design of functional proteins using tensorized energy calculations

por Maksymenko, Kateryna, Maurer, Andreas, Aghaallaei, Narges, Barry, Caroline, Borbarán-Bravo, Natalia, Ullrich, Timo, Dijkstra, Tjeerd M.H., Hernandez Alvarez, Birte, Müller, Patrick, Lupas, Andrei N., Skokowa, Julia, ElGamacy, Mohammad
Publicado 2023

P779: LONG-TERM COURSE OF HAX1-RELATED CONGENITAL NEUTROPENIA: AN ANALYSIS OF THE EUROPEAN SEVERE CHRONIC NEUTROPENIA INTERNATIONAL REGISTRY (SCNIR)

por Pogozhykh, Denys, Yilmaz Karapinar, Deniz, Klimiankou, Maksim, Gerschmann, Natali, Ebetsberger-Dachs, Georg, Palmblad, Jan, Carlsson, Göran, Masmas, Tania, Kinsey, Sally, Bartels, Marije, Mellor-Heineke, Sabine, Welte, Karl, Skokowa, Julia, Zeidler, Cornelia
Publicado 2023

Large-Scale Hematopoietic Differentiation of Human Induced Pluripotent Stem Cells Provides Granulocytes or Macrophages for Cell Replacement Therapies

por Lachmann, Nico, Ackermann, Mania, Frenzel, Eileen, Liebhaber, Steffi, Brennig, Sebastian, Happle, Christine, Hoffmann, Dirk, Klimenkova, Olga, Lüttge, Doreen, Buchegger, Theresa, Kühnel, Mark Philipp, Schambach, Axel, Janciauskiene, Sabina, Figueiredo, Constanca, Hansen, Gesine, Skokowa, Julia, Moritz, Thomas
Publicado 2015

The European Guidelines on Diagnosis and Management of Neutropenia in Adults and Children: A Consensus Between the European Hematology Association and the EuNet-INNOCHRON COST Acti...

por Fioredda, Francesca, Skokowa, Julia, Tamary, Hannah, Spanoudakis, Michail, Farruggia, Piero, Almeida, Antonio, Guardo, Daniela, Höglund, Petter, Newburger, Peter E., Palmblad, Jan, Touw, Ivo P., Zeidler, Cornelia, Warren, Alan J., Dale, David C., Welte, Karl, Dufour, Carlo, Papadaki, Helen A.
Publicado 2023